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29 Cards in this Set
- Front
- Back
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3 new classes of antibiotics
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fosfomycin trimethamine - synercid - oxazolidinones
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fosfomycin trimethamine is a phosphoric acid as an alternate treatment for ____
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UTIs
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fosfomycin trimethamine inhibits ____ ____ synthesis
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cell wall
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synercid is effective against ____ & ____ that causes endocarditis & ____ infections
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staphylococcus - enterococcus - surgical
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synercid inhibits ____ ____
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protein synthesis
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oxazolidinones is a new class of antibacterial drugs that inhibit initiation of ____ ____
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protein synthesis
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example drug of oxazolidinones is ____ which treat ____ & ____
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linezolid - MRSA - VRE
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fungal diseases are also know as _____
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mycoses
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2 types of fungal diseases
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cutaneous - systemic mycoses
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cutaneous mycoses is also know as ______
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dermatophytoses
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fungi have ____ that degrade keratin on skin hair and nails
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keratinase
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jock itch and athletes foot is an example of _____ _____
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fungi infection
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systemic mycoses is usually caused by ____ fungi
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soil
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people with suppressed immune system is likely to catch ____ pneumonia & ____ fever
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pneumocystis - valley
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2 antifungal drugs that attack plasma membrane
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polyenes - azoles
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polyenes mimic fungal ____ & bind to ____
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lipids - sterols
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2 examples of polyene drugs
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amphotericin B - nystatin
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anmphotericin B is versatile & effective for ____ & ____ treatments
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topical - systemic
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nystatin is a ____ treatment
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topical
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azoles disrupt ____ ____ structure
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fungal membrane
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3 examples of azole drugs
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ketoconazole (nizoral) - clotrimazole (lotrimin) - miconazole (monistat)
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antifungal drug that affect metabolism
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griseofulvin
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griseofulvin is an antifungal drug inhibiting metabolism & is used treat stubborn cases of ____ infections (jock itch, athletes foot)
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dermatophyte
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antifungal drug that inhibit nucleic acid synthesis
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flucytosine
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flucytosine is an analog of ____
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cytosine
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flucytosine is an antifungal drug inhibiting nucleic acid synthesis & is used to treat ____ mycoses or in combination with amphotericin B for ____ mycoses
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cutaneous - systemic
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2 major types of Antiparasitic drugs
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antimalarial - antihelminthic
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3 antimalarial drugs
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quinine - chloroquine- primaquine
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4 antiprotozoan drugs
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metronidazole - tetracyclines - quinacrine - sulfonamides
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