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24 Cards in this Set
- Front
- Back
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Syphilis incubation stage - duration
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3 wks
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Syphilis incubation stage - clinical setting
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no lesion - treponemes adhere + penetrate epithelium - multiplying + disseminate
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Syphilis incubation stage - diagnosis
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asymptomatic phase
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Syphilis incubation stage - treatment
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n/a
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Syphilis primary stage - duration
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2-6 wks
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Syphilis primary stage - clinical setting
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initial appearance of chancre at innoculation site - intense treponemal activity in body - chancre later disappears
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Syphilis primary stage - diagnosis
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dark-field microscopy - VDRL - FTA-ABS - MHA-TP testing
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Syphilis primary stage - treatment
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Benzathine PCN G 2x10⁶ units - aqueous benzyl or procaine PCN G 4.8x10⁶ units
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Syphilis primary latency stage - duration
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2-8 wks
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Syphilis primary latency stage - clinical setting
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healed chancre - little scarring - treponemes in blood - few if any symptoms
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Syphilis primary latency stage - diagnosis
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serological test (+)
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Syphilis primary latency stage - treatment
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Benzathine PCN G 2x10⁶ units - aqueous benzyl or procaine PCN G 4.8x10⁶ units
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Syphilis secondary stage - duration
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2-6 wks after chancre leaves
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Syphilis secondary stage - clinical setting
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skin - mucous membrane lesions - hair loss - patient highly infectious - fever - lymphadenopathy - symptoms can persist for months
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Syphilis secondary stage - diagnosis
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dark-field testing of lesions - serological tests (+)
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Syphilis secondary stage - treatment
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double doses of (Benzathine PCN G 2x10⁶ units - aqueous benzyl or procaine PCN G 4.8x10⁶ units)
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Syphilis latency stage - duration
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6 months to 8 or more years
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Syphilis latency stage - clinical setting
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treponemes quiescent unless relapse occurs - lesions can reappear
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Syphilis latency stage - diagnosis
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seropositive blood test
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Syphilis latency stage - treatment
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Benzathine PCN G 2x10⁶ units - aqueous benzyl or procaine PCN G 4.8x10⁶ units
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Syphilis tertiary stage - duration
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variable up to 20 years
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Syphilis tertiary stage - clinical setting
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neural, cardiovascular symptoms - gummas develop in organs - seropositivity
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Syphilis tertiary stage - diagnosis
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treponeme may be demonstrated by DNA analysis of tissue
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Syphilis tertiary stage - treatment
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Benzathine PCN G 2x10⁶ units - aqueous benzyl or procaine PCN G 4.8x10⁶ units
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