Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
81 Cards in this Set
- Front
- Back
|
True or False, The class of antibody is found in tears, saliva, milk, and mucous is IgM
|
False
|
|
|
True or False, The antibody classes that can cross the placental membranes is IgG
|
True
|
|
|
True or False, B cells encounter antigen in the thymus and bone marrow
|
False
|
|
|
True or False, The antibody dissplayed on the surface of B cells and used in clonal selection is IgD and monomeric IgM
|
True
|
|
|
True or False, B cells can differentiate into both memory and plasma cells
|
True
|
|
|
True or False, Plasma cells from a single B cell clone can secrete antibody specific for different antigens
|
False
|
|
|
True or False, Plasma cells from a single B cell clone can secrete IgG, IgM, and IgA
|
False
|
|
|
True or False, T helper cells have Cd4 which interacts with MHC I
|
False
|
|
|
True or False, M cells are found in the spleen
|
False
|
|
|
True or False, Dendritic cells activate T helper cells
|
True
|
|
|
MHC II molecules present what?
|
Extracellular antigen to CD4 T cells
|
|
|
CTLs recognize viral epitopes on the surface of virus-infected cells displayed in association with what?
|
MHC I
|
|
|
True or False, Tc cells are also known as T4 cells
|
False
|
|
|
Which of the following is not involved in the destruction of a virus infected cell?
|
Antibody
|
|
|
What kind of immunization? JD receives influenze immunization
|
Artificial active
|
|
|
What kind of immunization? Matt recieves antivenom following snake bite
|
Articficial passive
|
|
|
What kind of immunization? Tom recovers from measles
|
Natural Active
|
|
|
What kind of immunization? infant acquires sIgA after breast feeding
|
Natural Passive
|
|
|
True or False, Albumins are serum proteins made by the small intestine
|
False
|
|
|
True or False, Variolation involves the inoculation of cowpox into the skin
|
False
|
|
|
True or False, Inactivated vaccines stimulate both AMI and CMI
|
False
|
|
|
All of the following are subunit vaccines except
a) meningococcal meningitis b) influenze c) DTaP d) Haemophilus influenze b e) Measles, mumps, and rubella |
E
|
|
|
The D in DTaP is for diphtheria which is a what?
|
Toxoid
|
|
|
The poliovirus vaccine may contain what?
|
Infectious or inactivated virus
|
|
|
An example of recombinant vaccine?
|
Hepatitis B
|
|
|
True or False, The agglutination reaction can be used to indentify either antigen or an antibody
|
True
|
|
|
The viral hemagglutination test is used to test for presence of what?
|
Virus
|
|
|
True or False, No heemolysis in a complement fization test is a negative result
|
False
|
|
|
What is the mediator for hemolytic disease for a newborn
|
IgG/complement and cell surface protein
|
|
|
What is the mediator for peanuts
|
IgE and mast cells
|
|
|
What is the mediator for serum sickness
|
IgG/ complement and soluble antigen
|
|
|
What is the mediator for poison Ivy
|
Tc and Ti cells
|
|
|
Which of the following would be classified as an incitant?
|
Gold
|
|
|
Hemolytic disease of the newborn is due to a maternal immune response against what?
|
Fetal Rh factor
|
|
|
Immune complex reactions occur under which of the following conditions
|
High antigen load
|
|
|
What is the mediator for Grave's Disease?
|
IgG/ complement and cell surface protein
|
|
|
What is the mediator for Insulin dependent diabetes melitus?
|
Tc and Ti cells
|
|
|
What is the mediator for Myasthenia Gravis?
|
IgG/ complement and cell surface protein
|
|
|
Which of the following mediators is not associated with any autoimmune disease?
|
IgE
|
|
|
Agonist antibody against a TSH surface receptor is associated with what?
|
Graves Disease
|
|
|
Rheumatoid arthritis starts as a Type __ and progresses to Type __ hypersensitivity
|
3,4
|
|
|
A hypersensitivity to myelin basic protein associated with long axons?
|
Multiple sclerosis
|
|
|
Insulin dependent diabetes mellitis is characterized by what?
|
Selective destruction of pancreatic B-cells
|
|
|
DiGeorge syndrome is characterized by what?
|
Absence of a thymus
|
|
|
True of False, HIV is able to infect both T cells and Macrophages
|
True
|
|
|
True of False, HIV replication occurs when T helper cells are activated during and infection
|
True
|
|
|
True of False, CD4 T cell counts must be <200 to classifiy as having AIDS
|
False
|
|
|
True of False, The probability of acquiring AIDs from a contaminated needle stick is almost 100%
|
False
|
|
|
True of False,The incidence of AIDs in Texas is higher than the prevalence
|
False
|
|
|
True of False, Seroconversion following exposure to HIV takes up to 3 months
|
True
|
|
|
True of False, Penn State should be #1 in the BCS
|
True
|
|
|
Graft verses host disease is associated with
|
Bone Marrow Transplants
|
|
|
What is the Mechanism of penicillins?
|
Inhibit Cell wall synthesis
|
|
|
What is the Mechanism of fluoroquinolones?
|
Inhibit nucleic acid synthesis
|
|
|
What is the Mechanism of sulfonamides?
|
Competitive inhibition for folic acid production
|
|
|
What is the Mechanism of aminoglycosides?
|
Inhibit protein synthesis
|
|
|
What is the Mechanism of polymyxins?
|
Disrupt plasma membranes
|
|
|
The definiition of narrow spectrum antibiotic?
|
Kills all gram positive bacteria
|
|
|
Most antibiotics are produced by what?
|
Streptomyces
|
|
|
The definition of a broad spectrum antibiotic is what?
|
Kills both gram positive and gram negative bacteria
|
|
|
Methicillin resistant Staphylococcus aureus does what 4 things?
|
1) prduce penicillinase
2) have mutated penicillin binding proteins 3) cause 250,000 nosocomial infections per year 4) are resistant to all B lactam antibiotics |
|
|
The use of drug comination to trest infections does what?
|
Inhibits emergence of drug resistant mutants
|
|
|
Which of the following drug combinations is used to treat XDR tuberculosis?
|
INH, rifampin, fluorroquinone
|
|
|
Define antibody
|
Protein that are made in response to antigens and attach to specific antigens in a immune response
|
|
|
Define antibiotic
|
Microbial metabolic product with anti-microbial activity
|
|
|
Define Synergy
|
The use of 2 drugs to combat a disease that produces a greater effect that 1 additive of both seperates
|
|
|
Define HAART
|
A drug cocktail with reverse transcriptase inhibitors and protease inhibitors to combat HIV and AIDS
|
|
|
Define Allergen
|
Any environmental allergen that evokes a hyper sensitivity response
|
|
|
List the Five protective mechanisms of binding antibodies to antigens?
|
1) aggulation 2) antibody dependent cell mediated cytotoxicity 3) Neutralization 4) Opsonization 5) Activated of Complement
|
|
|
Sequence of amino acids within a protein recognized as foreign ______.
|
Epitope
|
|
|
Activated B cells develop into antibody secreting cells called _____ cells.
|
Plasma
|
|
|
Term for inoculation of cowpox virus into the skin?
|
Vaccination
|
|
|
Loss of self tolerance results in ______ disease
|
autoimmune
|
|
|
The use of drugs to treat a disease.______
|
Chemotherapy
|
|
|
Antibody-dependent cell-mediated cytotoxicity is a specific defense against what?
|
Large Parasites
|
|
|
An atopy would be a hereditary predisposition to develop a hypersensitivity to whivh of the follow?
|
Wasp Venoms
|
|
|
What are the Mediators for Multiple Sclerosis?
|
Tc and Ti Cells
|
|
|
What are the mediators for Syatemic lupus erthematosis?
|
IgG/Complement and soluble antigen
|
|
|
Narrow spectrum antibiotics cannot penetrate ____ in Gra negative cells
|
Outer Membrane
|
|
|
This Antibiotic changes shape of of the 30S ribsomal subunit and causes the messanger RNA code to be read incorrectly?
|
Streptomycin
|
|
|
What does HARRT stand for?
|
High Antibiotic Retrovirus Reverse Transcriptase
|
