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6 Cards in this Set

  • Front
  • Back
Define:
-transmembrane form of antibody
-transmits signals to the cell upon antigen binding
-receptor mediating internalization of antigen
B cell receptor
What family of cell adhesion molecules:
ICAM-1, ICAM2, CD2, CD4, CD8
Immunoglobulin superfamily
What binds addressins?
(carbohydrate ligands)
Selectins
(-Extracellular portion of molecule terminates in a lectin domain
-Bind to carbohydrate ligands, facilitating interactions between leukocytes and endothelial cells
What is the stimulatory co-signal needed to activate a naive T-cell?
CD28 --> B7
What is the inhibitory signal produced to modulate the immune response of an activated T cell?
CTLA-4 --> B7
What is the stimulatory co-signal needed to activate a B-cell?
CD40 --> CD40 ligand