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16 Cards in this Set
- Front
- Back
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A 50 yo woman presents with fever, cough, myalgias, some SOB, headache and diarrhea. She had inspiratory crackles, with low pulse ox and elevated AST and LDH. What does she have?
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SARS-associated coronavirus
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What is seen in the blood work of someone infected with SARS-CoV?
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low pO2, elevated AST, LDH and creatine kinase
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What is seen on chest X-ray in someone with SARS-CoV?
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lower lobe insterstitial infiltrates
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What does SARS stand for?
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severe acute respiratory syndrome
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What are the characteristics of the SARS-CoV?
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large enveloped virus, +ssRNA, irregular shape with club-shaped peplomers that looks like a CROWN SHAPE
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What is the longest RNA virus?
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SARS-CoV
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On electron micrograph how is SARS-CoV identified?
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crown like appearance
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What else is SARS-CoV called?
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group 4 coronavirus
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What are the different locations SARS-CoV can be found?
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nasopharyngeal aspirate, urine and stools
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How is SARS-CoV transmitted?
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respiratory droplets, fecal-oral, mechanical
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What is the incubation period of SARS-CoV?
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2-10 days
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Where do coronaviruses localize in the respiratory tract? what about SARS-CoV?
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1) upper
2) lower |
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What are the pathological lung changes that occur in someone with SARS-CoV?
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cytoarchitectural changes in infected cells, diffuse alveolar damage, multinucleated giant cells with NO viral inclusions
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What happens to respiratory epi with SARS-CoV infection?
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desqaumation
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With progression of SARS-CoV what is seen on histologic exam?
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diffuse alveolar damage with increased fibrosis, squamous metaplasia, and multinucleated giant cells
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How is SARS-CoV treated?
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supportive care
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