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10 Cards in this Set

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Noninfl. Diarrhea

Infants and toddlers
vomiting, fever, etc
Rotavirus
Rotavirus toxin pathogenesis:

Microvilli of sm intestin blunted,
mononuclear infiltrate in lamina propria, disacharidase activity down
Noninfl. Diarrhea

Norwalk virus
Pathogenesis of norwalk:

Jejunal biopsy = blunting, cytoplasmic vacuolization, decrease in brush border enzymes → malabsorption
Noninfl Diarrhea

Poultry, beef, gravies
MEXICAN FOOD
Clostridium perfringens

(Pathogenesis: Enterotoxin)
Noninfl Diarrhea

PROFUSE diarrhea w/ or w/o fever (rice water stool)
V. cholera
Pathogenesis:

Toxin stimulates adenylate cyclase and causes ↑ cAMP in the small intestine (no invasion or inflammation)
Noninfl Diarrhea

Undercooked or raw shellfish
Vibrio parahemolyticus
Pathogenesis:

Self limited, mimicks cholera, no clear enterotoxin. May have a rare dysentery form. hemosylins, phospholipase, and lysophospholipase
Noninfl Diarrhea

Undercooked fruits and veggies
Enterotoxigenic E. Coli
Pathogenesis

Heat labile toxin (LT) stimulates adenylate cyclase→efflux of water and ions
[ST→guanylate cyclase]
Noninlf Diarrhea

Enteropathogenic E Coli

(infants from shit countries, water, food , feco oral)
Adherence to enterocytes through pili damages adjoining microvilli
Noninfl Diarrhea

Food, feco-oral HAMBURGER

bloody and watery diarrhea
Enterohemorrhagic E. Coli
Pathogenesis:

Verotoxin, which is a cytotoxin, causes bloody diarrhea with NO invasion of the organism
Noninfl Diarrhea

daycare, CAMPING, beavers, dogs

loose, pale, greasy diarrhea.
mild malabsorption syndrome
Giardia Lamblia
Pathogenesis

Cysts ingested, excyst in duodenum and jejunum, multiply and attach to intestinal villi by sucking disk
Noninfl Diarrhea

Day care, homosexuals (AIDS)
Cryptosporidium parvum

Sx indefinite duration in AIDS
Pathogenesis:

Sporozoites attach to the epithelial surface of the intestine and replicate