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10 Cards in this Set
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Noninfl. Diarrhea
Infants and toddlers vomiting, fever, etc |
Rotavirus
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Rotavirus toxin pathogenesis:
Microvilli of sm intestin blunted, mononuclear infiltrate in lamina propria, disacharidase activity down |
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Noninfl. Diarrhea
Norwalk virus |
Pathogenesis of norwalk:
Jejunal biopsy = blunting, cytoplasmic vacuolization, decrease in brush border enzymes → malabsorption |
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Noninfl Diarrhea
Poultry, beef, gravies MEXICAN FOOD |
Clostridium perfringens
(Pathogenesis: Enterotoxin) |
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Noninfl Diarrhea
PROFUSE diarrhea w/ or w/o fever (rice water stool) |
V. cholera
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Pathogenesis:
Toxin stimulates adenylate cyclase and causes ↑ cAMP in the small intestine (no invasion or inflammation) |
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Noninfl Diarrhea
Undercooked or raw shellfish |
Vibrio parahemolyticus
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Pathogenesis:
Self limited, mimicks cholera, no clear enterotoxin. May have a rare dysentery form. hemosylins, phospholipase, and lysophospholipase |
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Noninfl Diarrhea
Undercooked fruits and veggies |
Enterotoxigenic E. Coli
|
Pathogenesis
Heat labile toxin (LT) stimulates adenylate cyclase→efflux of water and ions [ST→guanylate cyclase] |
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Noninlf Diarrhea
Enteropathogenic E Coli (infants from shit countries, water, food , feco oral) |
Adherence to enterocytes through pili damages adjoining microvilli
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Noninfl Diarrhea
Food, feco-oral HAMBURGER bloody and watery diarrhea |
Enterohemorrhagic E. Coli
|
Pathogenesis:
Verotoxin, which is a cytotoxin, causes bloody diarrhea with NO invasion of the organism |
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Noninfl Diarrhea
daycare, CAMPING, beavers, dogs loose, pale, greasy diarrhea. mild malabsorption syndrome |
Giardia Lamblia
|
Pathogenesis
Cysts ingested, excyst in duodenum and jejunum, multiply and attach to intestinal villi by sucking disk |
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Noninfl Diarrhea
Day care, homosexuals (AIDS) |
Cryptosporidium parvum
Sx indefinite duration in AIDS |
Pathogenesis:
Sporozoites attach to the epithelial surface of the intestine and replicate |