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44 Cards in this Set
- Front
- Back
What is the difference between an infection and an intoxication?
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An infection occurs as a result of a pathogenic organism present in the consumed food; An intoxication occurs as a result of a chemical or a toxin in the consumed food
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Name to species of microorganisms that can cause intoxication.
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S. aureus - enterotoxin
C. botulinum - neurotoxin (Botulism) |
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Name four infections caused by FBDs.
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1 Salmonellosis
2 C. perfringens Illness 3 B. cereus gastroenteritis 4 Enteropathogenic E. coli Inf. |
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Intoxication or infection?
Yersiniosis |
Invasive infection (Yersinia enterocolitica
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Intoxication or infection?
Shigellosis |
Shiga Toxin: enterotoxic, neurotoxic and cytotoxic (Shigella dystenteriae - only 10 cells may cause illness)
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Intoxification or infection?
Vibrio parahaemolyticus Illness |
Invasive infection
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Intoxification or infection?Listeriosis
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Invasive infection
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Are Gram positive or Gram negative bacteria more likely to be responsible for FBDs and why?
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Gram negative; The external LPS layer consists of an endotoxin (Lipid A) that can trigger fever and septic shock; LPS also protects cell from phagocytosis, penicillin, and the antibacterial enzyme lysozyme
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Which layer is thicker in a Gram positive bacteria and causes it to be more sensitive to the actions of lysozyme and penicillin
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Peptidoglycan
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What is the most prevalent cause of FBD per the powerpoint's data from the 1990s?
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Campylobacter
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Which organism can be responsible for the FBD symptoms of septicemia and still births?
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Listeria monocytogenes
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Which organism can be responsible for the FBD symptom of arthritis?
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Yersinia enterocolitica
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Which organism can be responsible for the FBD symptom of muscle pains?
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Trichina spiralis
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How are microbial diseases of the digestive system usually transmitted?
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Fecal-oral cycle
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Where are most normal microbiota found in the body?
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In the mouth and large intesting
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Why are there no (or hardly any) microbiota in the stomach and small intestine?
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Hydrochloric acid in the the stomach and the rapid movement of food through the small intestine
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Where are Paneth cells and what are two of their functions?
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They are found in the small intestine; they are capable of phagocytizing bacteria and produce antibacterial proteins called defensins
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What is the function of M cells?
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To translocate antigens and microorganisms to the other side of the epithelium where they can contact lymphoid tissues (Peyer's patches) to initiate and immune response
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What is dysentery?
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Severe diarrhea accompanied by blood or mucus
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What is gastroenteritis?
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A disease which causes inflammation of the stomach and intestinal mucosa
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What is botulism?
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A special case of intoxication that affects the nervous system (rather than the GI tract)
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Gastroenteritis is most commonly caused by what organism?
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S. aureus (Staphylococcus areus)
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What are some examples of high risk foods for containing S. aureus?
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Custards, cream pies, and ham
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How is staphyloccocal food poisoning usually diagnosed?
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Based on the symptoms and especially short incubation time
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What is the best way to avoid staphylococcal food poisoning?
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Adequate refrigeration during storage periods; it is heat stable and will not be killed when reheating
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What are the signs and symptoms of Shigellosis (aka bacillary dysentery)?
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Longer incubation periods of 12 hours to two weeks; can cause as many as 20 bowel movements/day, abdominal cramps and fever; severity may vary depending on species (Gram -)
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How is Shigellosis spread?
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Not found in animals and spread only from person to person; often found in family, day-care, and similar settings
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What are the signs and symptoms of Salmonellosis (aka Salmonella gastroenteritis)?
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Incubation time of 12-36 hours; moderate fever, nausea, abdominal pain and cramps, and diarrhea (Gram -)
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What are the sources of Salmonellosis?
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Meat (found in the intestinal tracts of many animals), pet reptiles, chickens and their eggs; bacteria is killed with proper cooking but is sometimes left on cooking tools
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What causes typhoid fever?
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The most virulent serotype of Salmonella, S. typhi
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Where is S. typhi found and what are ways to eliminate it?
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Only in the feces of humans; Proper sewage disposal, water treatment, and food sanitation
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What is the incubation period of typhoid fever and where do S. typhi multiply?
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Incubation is 2-3 weeks; They multiply within phagocytic cells and are disseminated into multiple organs, especially the spleen and liver, it will eventually get into the blood stream
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What are the symptoms of typhoid fever?
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Severe fever and headache, diarrhea only during the 2nd or 3rd week at which time the fever will subside; in severe cases ulceration and perforation of the intestinal wall can occur
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What is cholera and what are its symptoms?
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It is one of the most serious gastrointestinal diseases (Vibrio cholerae); symptoms include "rice water stools" and violent vomiting, usually no fever
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What happens internally when v. cholera is present?
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They grow in the small intestine and produce a toxin that causes the host to secrete water and electrolytes, especially potassium, which results in watery stools containing masses of intestinal mucus and epithelial cells
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Where is v. cholera found?
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In salt water and sometimes fresh water; they form biofilms and colonize on tiny crustaceans, algae, aquatic plants, and plankton
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What is the most common cause of "traveler's diarrhea"?
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Pathogenic strains of E. coli; most common pathogenic strain is enterotoxigenic E. coli (ETEC)
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Which bacteria are the leading cause of foodborne illness in the U.S.?
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Campylobacter (most commonly C. jejuni)
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What is the primary source of Campylobacter?
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Almost all of retail chicken is contaminated
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Which microbe is responsible for peptic ulcer disease?
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Helicobacter pylori
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What is the most common cause of VIRAL gastroenteritis?
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Rotavirus
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Name the mycotoxin produced by the fungus A. flavus, a common mold, which known to contaminate peanuts along with other foods.
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Aflatoxin
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What is ergot poisoning (ergotism)?
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A mycotoxin produced by C. purpurea which results from the ingestion of rye or ther cereal grains contaminated with the fungus
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Name the prolonged diarrheal disease caused by a flagellated protozoan which attaches to the intestinal wall of humans.
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Giardiasis; Caused by Giardia lamblia
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