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40 Cards in this Set

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Microscopy

Discovery of the very small

Robert Hooke

Published Micrographia in 1665.


Led to discovery of the cell

Anton von Leeuwenhoek

Created the single-lens microscope.


Discovered tiny, living animals using his microscope, which he called animalcules

Single-lens Microscope

Spontaneous Generation

Suggested that some forms of life could arise from nonliving, decaying matter if provided with the "vital force"

Francesco Redi

Italian naturalist who, in 1668, performed one of history's first known biological experiments. His experiment was designed to test whether maggots could arise spontaneously from rotting meat

Louis Pasteur

French chemist who, in 1861, proved spontaneous generation of animalcules is not possible. Proposed germs cause infectious disease, and created pasteurization to kill pathogens. Proved yeast causes fermentation.

Edward Jenner

In 1796, determined that disease (smallpox) could be prevented through vaccination using a similar but milder disease causing bacteria

Miasma

a highly unpleasant or unhealthy smell or vapor. Does not transmit disease

Disease Transmission

Transmitted from person to person by direct or indirect contact. Viruses, bacteria, parasites, and fungi all cause infectious disease. Malaria, measles, and respiratory illnesses are examples of infectious diseases.

Ignaz Semmelweis

Hungarian obstetrician who, in 1847, determined the source of puerperal fever or blood poisoning of women and children by medical staff not washing their hands

Puerperal Fever

fever caused by uterine infection following childbirth

John Snow

An English surgeon who, in 1854, discovered the cause of cholera transmission in London. Discovered you can interrupt disease, which he did by having a street pump handle removed from a water source

Joseph Lister

Developed antisepsis by using carbolic acid, phenol, spray on open wounds


Demonstrated germs can come from the environment and can be controlled through cleanliness


Robert Koch

Koch's postulates became standards for linking a specific organism to a specific disease.


Developed pure culture techniques; by adding gelatin to his broth, he was able to grow bacterial colonies in a petri dish

Fanny Hesse

Used agar to solidify jams, jellies, creating an ideal mix for bacterial culture

Ivanowsky and Beijerinck

Their observations of filterable viruses showed that liquid filtrate causes tobacco mosaic disease

Walter Reed

Said that a filterable viruses causes yellow fever in humans

Anton de Bary

Studied Fungi linked to plant diseases

Charles Laveran

Discovered a protozoan parasite in blood caused malaria

Winogradsky

Recognized the beneficial roles of nitrogen fixing bacteria in soil

Prokaryotes

A microscopic single-celled organism that has neither a distinct nucleus with a membrane nor other specialized organelles. Prokaryotes include the bacteria and cyanobacteria.


Over 10 million different species that are spherical, spiral, or rod shaped.


Have 2 domains (bacteria and archaea)



Viruses

Are not microbes or cells (not cellular and cannot be grown in pure culture).


Have a DNA or RNA core surrounded by a protein coat.


Cannot replicate without a host cell.


Over 100 million types.

Fungi

Around 100,000 species.


Most live in their food medium and may cause human disease.


Some make useful antibiotics or help flavor foods

Protists

Single celled protozoa and algae.


Some are free living and some live symbiotically with other organisms.


Some can cause disease in humams.

Beadle and Edward

Using fungus, demonstrated that one gene codes for one enzyme

Luria and Delbrück

Used E. coli to show that mutations could occur spontaneously

Avery, MacLeod and McCarty

Suggest DNA is the genetic material in cells by using the bacterial organism Streptococcus pneumoniae

Hershey and Chase

Confirmed DNA as the substance of the genetic material by using a virus to infect bacterial cells

Crick

Used E. coli and a virus to show how the DNA genetic code works to make individual proteins

Eukaryotic cells

eu = true karyon = nucleus


Plant, animal, fungi, protist.


Contain a membrane-bound nucleus and organelles

Antibiotics

Used to cure infectious disease.


However, many pathogens are becoming resistant to antibiotics.

Erlich

Developed Salvarsan, a chemical that cured individuals or syphilis

Fleming

Observed that a species of Penicillin mold killed bacterial cells

Chain and Florey

Developed penicillin

Bioterrorism

Intentional use of biological agents to cause fear or death

Global warming can cause?

Larger spread of disease

Microbiology today is concerned with...

The relationship of microorganisms with their environment

Microbial Evolution

Represents a model system to observe evolutionary processes

5 Major Microbial Groups

Bacteriology - study of bacteria


Virology - study of viruses


Mycology - study of fungi


Protozoology - study of protozoa


Phycology - study of the algae