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49 Cards in this Set
- Front
- Back
action of diphtheria toxin
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inhibits protein synthesis by ADP ribosylation of elongation factor 2.
treat with antitoxin and prevent with toxoid immunization |
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effect of P. aeruginosa toxin
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exotoxin A inhibits protein synthesis by ADP ribosylation of elongation factor 2.
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Neisseria gonorrhea
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gram negative diplococcus.
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Neisseria gonorrhea endotoxin
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lipooligosaccharide
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Neisseria gonorrhea, distinguishing enzyme
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oxidase positive
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Neisseria gonorrhea cultured on
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chocolate agar (modified Thayer-Martin)
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Neisseria gonorrhea resistance to phagocytosis
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pili that attach to mucosal surfaces, antigenic change prevent immunity.
Capsule. Protein I. |
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Neisseria gonorrhea special enzyme to stick to mucosal walls
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IgA protease
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Neisseria gonorrhea fermentation
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only glucose
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Neisseria gonorrhea treatment
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PCN or if allergic use
ceftriaxone or macrolide |
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Francisella tularensis
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gram negative rod, can survive in macrophages for a long time
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Francisella tularensis transmission
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ticks on wild rabbits.
cleaning animals hides, aerosol, insect bite |
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Francisella tularensis MC clinical presentation
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ulceroglandular disease
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Francisella tularensis requirement for growth
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cysteine
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Francisella tularensis treatment
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macrolide
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Campylobacter jejuni
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comma/S-shaped gram negative rod. grows at 42 C
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Campylobacter jejuni transmission
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ingestion of poultry, milk, water
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Campylobacter jejuni most common cause of:
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bacterial gastroenteritis in USA
bloody diarrhea |
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Campylobacter jejuni associated with
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Guillain Barre syndrome. antibodies cross react with neurons
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Campylobacter jejuni treatment
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macrolide
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MCC of OM in children
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Strep. pneumoniae
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MCC of otitis externa
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Pseudomonas
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Hemophilus influenza
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gram negative coccobacilli. requires X and V factor for growth. (hemin and NAD)
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macrophages
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multilobulated nucleus with granules. previously monocytes. microglial cells in the CNS and reservoir of HIV in CNS.
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clue cell
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gardnerella vaginalis infection
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sporothricosis
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prick of thorn from a rose. prick from a lobster spine
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patient sticks himself with a knife and develops trismus
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tetanus
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treatment for Pneumocystitis carinii
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trim-sulfa
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budding yeast with narrow base bud
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cryptococcus neoformans.
treat with amphotericin |
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DOC for chlamydia
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doxycycline
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chocolate agar
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contains blood which supports growth of bacteria
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child with menigitis and picture of gram neg diplococcus
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N. meningitidis. capsule, endotoxin (lipopolysaccharide), IgA protease.
Tx: PenG |
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Microflora of nasopharynx
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anaerobic bacteria, S. viridans, coagulase negative staph, avirulent Hemophilus and N. meningitdis.
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Microflora of skin
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coagulase negative staph; also S. aureus, Corynebacteria, Propionibacter, C perfringens, Candida, Malassezia
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narrow angled septate hyphae and fruiting body
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Aspergillus
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Coccidioidomycosis
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Southwest, arthrospores in dust
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recurrent painful vesicles around mouth
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HSV I
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Complementation in defective virus
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replication of another virus provides missing function required by the mutant virus
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Initial defense against Salmonella in the blood
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endotoxins released by bacteria activate the alternative complement system
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Self-induced abortion
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cervical swab and put into anaerobic medium for Clostridium
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SCID with adenosine deaminase deficiency
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adenine buildup toxic to B and T cells, accumulation of dATP which inhibits ribonucletodie reductase with subsequent decrease in deoxynucleoside triphosphate precursors for DNA.
BM tranplant helpful |
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Spirochetes in synovial fluid
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Lyme's disease due to Borrelia burgdorferi
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Infertile woman with scarred fallopian tubes
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Chlamydia trachomatis MCC
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J-K disease from brain instrument treated with formaldehyde
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prions
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Coxsackie
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MCC of myocarditis and pericarditis
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Listeria
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gram positive rod, tumbling motility, pregnant woman should not eat soft cheese
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wound infection
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gram positive cocci = S. aureus
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middle aged woman with menigitis
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S. pneumo gram positive diplococcus
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gram positive rod resistant to heat
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bacillus anthracis
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