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108 Cards in this Set
- Front
- Back
What causes Syphillis?
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Treponema pallidum
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Give 3 AKAs for syphillis.
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1) Great Pox
2) Lues 3) Bad Blood |
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Silver stain and darkfield condensor are used to see which bateria?
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Treponema pallidum
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whitlow lesion
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Treponema pallidum
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Stages of Syphillis?
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1) primary
2) secondary 3) tertiary 4) latency |
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Chancre lesion
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Treponema pallidum
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What is the most contagious stage of Syphillis?
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Secondary stage
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Lesions on palms and soles of feet in the Secondary stage of this disease?
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Syphillis
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What bacteria causes Lyme's Disease?
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Borrelia burgdorferi
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What is the morphology of Borrelia burgdorferi?
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spirochete
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Bull's eye lesion
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Borrelia burgdorferi
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Which bacteria has Endoflagella?
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Borrelia burgdorferi
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AKA for endoflagella?
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axial filaments
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How is Borrelia burgdorferi transmitted?
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Transovarian transmission form Ixodes tick (hard shelled)
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Name the reservoirs (2) for Borrelia burgdorferi.
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1) white footed field mice
2) white tailed deer |
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Name the diagnostic lesion of Lyme's Disease.
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erythema chronicum migrans (Bulls-eye lesion)
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What are the 3 stages of Lyme's Disease?
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1) Bulls-eye lesion
2) swollen knees, arthritis, cardiac problems, muscle pain, meningitis 3) CNS/heart problems, swollen joints, swollen face |
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Lab Dx for Borrelia burgdorferi?
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1) PCR assay
2) IgM antibodies 3) IgG antibodies |
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Unicellular eukaryotic organisms?
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Protozoa
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Classification of Protozoa (2)?
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1) Locomotion or method of motility
2) Location of pathogenicity |
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Which 3 protozoa move via pseudopods?
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1) Entamoeba histolytica
2) Naegleria fowleri 3) Acanthamoeba species |
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What does PCP stand for?
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pneumocystis pneumonia
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Pnsumocystis jirovecii was formerly known as what?
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Pneumocystis carinii
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Which fungus lead to the discovery of AIDS?
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Pneumocystic jirovecii
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Pneumocystic jirovecii was formerly classified as ______ but is now classified as ________.
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-protozoan
-fungus |
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What is the leading cause of death in AIDS patients?
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Pneumocystis jirovecii
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What is a common complication of PCP?
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pneumothorax
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Which fungus attacks interstitial, fibrous tissue of the lungs, thickening of alveolar septa and alveoli which cause hypoxia?
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Pneumocystis jirovecii
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What is done to culture Pneumocystis jirovecii?
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-sputum or bronchio-alveolar lavage sample is taken
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Name 4 things used in the diagnosis of PCP.
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"PIST"
1) periodic acid schiff stain 2) immunofluorescent assay 3) silver nitrate 4) toluidine blue |
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Name 5 systemic fungi.
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1)Coccidioides immitus
2) Histoplasma capsulatum 3) Blastomyces dermatitidis 4) Paracoccidioides brasiliensis 5) Cryptococcus neoformans |
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AIDS alerted thhe CDC of the presence of Pneumocystic jirovecii due to doctors requesting which drug?
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pentamidine
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PCP only found in (3)?
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1) malnourished/premature babies (x-linked autosomal recessive with IgM syn)
2) severely immunocompromised due to cancer 3) drug abusers------>AIDS patients |
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What does Pneumocystic jivorvecii lack in its cell wall?
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ergosterol
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Gummas of the skin, soft tissue and bone
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Tertiary syphilis
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What is the AKA for systemic mycoses?
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Deep seated mycoses
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Fungus that can be transmitted from soil with pigeon feces?
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Cryptococcus neoformans
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How are systemic mycoses transmitted?
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inhalation of conidia, then spreatd systemically
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All systemic mycoses are dimorphic, except?
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cryptococcus neoformans (YEAST ONLY)
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Hyphae, forms alternating, barrel shaped arthrospore conidia?
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coccidioides immitus (MOLD)
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endosporulating sphereule with many yeast inside?
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Coccidioides immitus (YEAST)
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Geographic occurance of Coccidioides immitus?
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southwestern USA
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Which 2 systemic mycoses occure east of the mississippi river?
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1) Histoplasma capsulatum
2) Blastomyces dermitidis |
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Geographic occurrance of Paracoccidioides braziliensis?
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central and south america
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Septate hyphae, forms tuberculated macrocondida?
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Histoplasma capsulatum (MOLD)
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Tiny cigar shaped yeast
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Histoplasma capsulatum
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Septate hyphae, forms conidia that have lollipop appearance?
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Blastomyces dermitidis (MOLD)
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Very large, double walled, with broad based budding?
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Blastomyces dermitidis (YEAST)
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Round with multiple cigar shaped buds called ship wheel formation?
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Paracoccidioides braziliensis (YEAST)
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Round yeast with polysaccharide capsule?
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Cryptococcus neoformans
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Which fungus can be diagnosed with a CSF sample and India Ink prep and culture?
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Cryptococcus neoformans
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Lab DX for Coccidioides immitus?
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1) sputum sample
2) KOH prep |
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Lab Dx for Histoplasma capsulatum?
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1) sputum sample
2) culture of Smith's media 3) Sabouraud agar |
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Lab Dx for Blastomyces dermitidis?
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1) Sputum or skin lesion sample
2) Sabouraud agar |
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Lab Dx for Paracoccidioides braziliensis?
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1) Tissue sample from lesion area
2) Can culture |
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Which systemic mycoses can cause meningitis?
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Cryptococcus neoformans
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coccidiomycosis
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Coccidioides immitus
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San Juaquin Valley Fever
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Coccidioides immitus
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Darling's disease
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Histoplasma capsulatum
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Spelunker's lung
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Histoplasma capsulatum
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Cave disease
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Histoplasma capsulatum
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Which systemic mycoses are found in chicken coups?
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Histoplasma capsulatum
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Which systemic mycoses can be found in bat caves?
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Histoplasma capsulatum
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Which systemic mycoses mimics TB of Xray?
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Histoplasma capsulatum
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Gilchrist's disease
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Blastomycosis dermatitidis
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North American Blastomycosis
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Blastomycosis dermatitidis
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South American Blastomycosis
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Paracoccidioides brasiliensis
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Which systemic mycoses are females protected against due to their hormones?
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Paracoccidioides brasiliensis
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Which fungus is found in pigeon feces?
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Cryptococcus neoformans
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Which fungus is hidden by a large polysaccharide capsule which prevents phagocytosis?
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Cryptococcus neoformans
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Which fungus is normal flora of the large intestines, vagina, and skin?
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Candida albicans
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What is the AKA for candidiasis?
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monilia
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What type of fungus is Candida albicans?
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opportunistic
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What is the morphology of Candida albicans?
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-blastoconidia, pseudophyphae, hyphae
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Types of infections caused by Candida albicans (8)?
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1) oral thrush
2) GI tract 3) Vaginitis 4) Cutaneous (bartenders/housewives) 5) Intertrio (b/t fingers and toes; under breast fold) 6) onychia (nails) 7) paronychia (cuticles) 8) systemic |
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Lab Dx for Candida albicans?
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-all stain Gram positive
-grows overnight -rapid test: germ tube test -biochemicals |
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Which fungus causes Desert Rheumatism?
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Coccidioides immitus
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Black colonies grown on Birdseed agar?
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Cryptococcus neoformans
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Morphology of Treponema pallidum?
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-corkscrew shaped
-Gram negative -endoflagella |
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Which bacteria fails Koch's 2nd postulate?
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Treponema pallidum
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How is Treponema pallidum transmitted (3)?
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1) sexual
2) transplacental 3) accidental |
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What is the most advanced stage of neurosyphillis?
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Paresis:
personality, affect, reflexes, eyes, sensorium, intellect, speech. |
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What is the most florid stage of syphillis?
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Secondary stage
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What 2 things are used for screening and monitor therapy of syphillis?
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1) VDRL
2) RPR |
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Characteristics of congenital syphillis?
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1) rhinitis (snuffles)
2) saddle nose 3) maculopapular rash 4) Hutchinson's teeth - Mulberry molars 5) Saber shins 6) Interstitial keratitis |
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Which serology tests detect Reagin antibodies of Syphillis?
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1) VDRL
2) RPR Flocculation |
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What is the lab reagent used to detect syphillis?
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cardiolipin
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VDRL and RPR
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Serology test for syphillis that is SENSITIVE, NON-SPECIFIC.
Non-treponemal tests. FALSE (+) Good for SCREENING. QUANTITATIVE |
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Which serology tests detect antibodies to surface antigens of spirochetes in syphillis?
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1) FTA-ABS
2) MHA-TB |
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FTA-ABS and MHA-TB
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QUALITATIVE test
Treponemal tests Confirmatory tests False (+) |
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How is congenital syphillis diagnosed?
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Check for IgM antibodies.
Take mother's blood. Newborns have IgG from mother. |
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What are the 2 groups of Phylum Platyhelminthes (flatworms)?
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1)Class Cestoda (tapeworms)
2)Class Trematoda (flukes) |
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Morphology of Class Cestoda (tapeworms)
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1) long, ribbon-like
2) dorsally flattened, and segmented 3) NO digestive, respiratory, or vascular systems 4) Hermaphrodites |
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Each segment of a flatworm is called?
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Proglottin
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What is the self-contained reproductive unit of a flatworm called?
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Proglottin
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Summation of proglottids?
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Strobila
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Name the 3 parts of a tapeworm.
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1) Scolex head
2) neck 3) Strobila |
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What do you call a crown of hooks on a scolex head?
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Rostellum
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Function of a scolex head?
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Used as an attachments to the intestines
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Where do proglottids begin to mature?
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the neck
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Eggs of tapeworms are called?
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onchosphere
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Onchosphere contain what type of embryos?
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hexacanth
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What is the definitive host of tapeworms?
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humans
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Which class are flukes in?
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Trematoda
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What are the 1st hosts in all flukes?
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snails
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Swimmers of flukes are called?
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cercariae
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All Trematodes, EXCEPT Schistosoma are:
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1) bilaterally symmetrical
2) leaf-shaped 3) hermaphrodites 4) produce operculated eggs 5) 2 intermediate hosts |
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Including Shistosoma, Trematodes have the following:
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1) Blind digestive system
2) Excretory system has flame cells (primitive kidney) 3) 2 suckers (oral & ventral) 4) Long life span |