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108 Cards in this Set

  • Front
  • Back
What causes Syphillis?
Treponema pallidum
Give 3 AKAs for syphillis.
1) Great Pox

2) Lues

3) Bad Blood
Silver stain and darkfield condensor are used to see which bateria?
Treponema pallidum
whitlow lesion
Treponema pallidum
Stages of Syphillis?
1) primary
2) secondary
3) tertiary
4) latency
Chancre lesion
Treponema pallidum
What is the most contagious stage of Syphillis?
Secondary stage
Lesions on palms and soles of feet in the Secondary stage of this disease?
Syphillis
What bacteria causes Lyme's Disease?
Borrelia burgdorferi
What is the morphology of Borrelia burgdorferi?
spirochete
Bull's eye lesion
Borrelia burgdorferi
Which bacteria has Endoflagella?
Borrelia burgdorferi
AKA for endoflagella?
axial filaments
How is Borrelia burgdorferi transmitted?
Transovarian transmission form Ixodes tick (hard shelled)
Name the reservoirs (2) for Borrelia burgdorferi.
1) white footed field mice

2) white tailed deer
Name the diagnostic lesion of Lyme's Disease.
erythema chronicum migrans (Bulls-eye lesion)
What are the 3 stages of Lyme's Disease?
1) Bulls-eye lesion

2) swollen knees, arthritis, cardiac problems, muscle pain, meningitis

3) CNS/heart problems, swollen joints, swollen face
Lab Dx for Borrelia burgdorferi?
1) PCR assay
2) IgM antibodies
3) IgG antibodies
Unicellular eukaryotic organisms?
Protozoa
Classification of Protozoa (2)?
1) Locomotion or method of motility

2) Location of pathogenicity
Which 3 protozoa move via pseudopods?
1) Entamoeba histolytica
2) Naegleria fowleri
3) Acanthamoeba species
What does PCP stand for?
pneumocystis pneumonia
Pnsumocystis jirovecii was formerly known as what?
Pneumocystis carinii
Which fungus lead to the discovery of AIDS?
Pneumocystic jirovecii
Pneumocystic jirovecii was formerly classified as ______ but is now classified as ________.
-protozoan

-fungus
What is the leading cause of death in AIDS patients?
Pneumocystis jirovecii
What is a common complication of PCP?
pneumothorax
Which fungus attacks interstitial, fibrous tissue of the lungs, thickening of alveolar septa and alveoli which cause hypoxia?
Pneumocystis jirovecii
What is done to culture Pneumocystis jirovecii?
-sputum or bronchio-alveolar lavage sample is taken
Name 4 things used in the diagnosis of PCP.
"PIST"

1) periodic acid schiff stain
2) immunofluorescent assay
3) silver nitrate
4) toluidine blue
Name 5 systemic fungi.
1)Coccidioides immitus
2) Histoplasma capsulatum
3) Blastomyces dermatitidis
4) Paracoccidioides brasiliensis
5) Cryptococcus neoformans
AIDS alerted thhe CDC of the presence of Pneumocystic jirovecii due to doctors requesting which drug?
pentamidine
PCP only found in (3)?
1) malnourished/premature babies (x-linked autosomal recessive with IgM syn)

2) severely immunocompromised due to cancer

3) drug abusers------>AIDS patients
What does Pneumocystic jivorvecii lack in its cell wall?
ergosterol
Gummas of the skin, soft tissue and bone
Tertiary syphilis
What is the AKA for systemic mycoses?
Deep seated mycoses
Fungus that can be transmitted from soil with pigeon feces?
Cryptococcus neoformans
How are systemic mycoses transmitted?
inhalation of conidia, then spreatd systemically
All systemic mycoses are dimorphic, except?
cryptococcus neoformans (YEAST ONLY)
Hyphae, forms alternating, barrel shaped arthrospore conidia?
coccidioides immitus (MOLD)
endosporulating sphereule with many yeast inside?
Coccidioides immitus (YEAST)
Geographic occurance of Coccidioides immitus?
southwestern USA
Which 2 systemic mycoses occure east of the mississippi river?
1) Histoplasma capsulatum

2) Blastomyces dermitidis
Geographic occurrance of Paracoccidioides braziliensis?
central and south america
Septate hyphae, forms tuberculated macrocondida?
Histoplasma capsulatum (MOLD)
Tiny cigar shaped yeast
Histoplasma capsulatum
Septate hyphae, forms conidia that have lollipop appearance?
Blastomyces dermitidis (MOLD)
Very large, double walled, with broad based budding?
Blastomyces dermitidis (YEAST)
Round with multiple cigar shaped buds called ship wheel formation?
Paracoccidioides braziliensis (YEAST)
Round yeast with polysaccharide capsule?
Cryptococcus neoformans
Which fungus can be diagnosed with a CSF sample and India Ink prep and culture?
Cryptococcus neoformans
Lab DX for Coccidioides immitus?
1) sputum sample

2) KOH prep
Lab Dx for Histoplasma capsulatum?
1) sputum sample

2) culture of Smith's media

3) Sabouraud agar
Lab Dx for Blastomyces dermitidis?
1) Sputum or skin lesion sample

2) Sabouraud agar
Lab Dx for Paracoccidioides braziliensis?
1) Tissue sample from lesion area

2) Can culture
Which systemic mycoses can cause meningitis?
Cryptococcus neoformans
coccidiomycosis
Coccidioides immitus
San Juaquin Valley Fever
Coccidioides immitus
Darling's disease
Histoplasma capsulatum
Spelunker's lung
Histoplasma capsulatum
Cave disease
Histoplasma capsulatum
Which systemic mycoses are found in chicken coups?
Histoplasma capsulatum
Which systemic mycoses can be found in bat caves?
Histoplasma capsulatum
Which systemic mycoses mimics TB of Xray?
Histoplasma capsulatum
Gilchrist's disease
Blastomycosis dermatitidis
North American Blastomycosis
Blastomycosis dermatitidis
South American Blastomycosis
Paracoccidioides brasiliensis
Which systemic mycoses are females protected against due to their hormones?
Paracoccidioides brasiliensis
Which fungus is found in pigeon feces?
Cryptococcus neoformans
Which fungus is hidden by a large polysaccharide capsule which prevents phagocytosis?
Cryptococcus neoformans
Which fungus is normal flora of the large intestines, vagina, and skin?
Candida albicans
What is the AKA for candidiasis?
monilia
What type of fungus is Candida albicans?
opportunistic
What is the morphology of Candida albicans?
-blastoconidia, pseudophyphae, hyphae
Types of infections caused by Candida albicans (8)?
1) oral thrush
2) GI tract
3) Vaginitis
4) Cutaneous (bartenders/housewives)
5) Intertrio (b/t fingers and toes; under breast fold)
6) onychia (nails)
7) paronychia (cuticles)
8) systemic
Lab Dx for Candida albicans?
-all stain Gram positive
-grows overnight
-rapid test: germ tube test
-biochemicals
Which fungus causes Desert Rheumatism?
Coccidioides immitus
Black colonies grown on Birdseed agar?
Cryptococcus neoformans
Morphology of Treponema pallidum?
-corkscrew shaped
-Gram negative
-endoflagella
Which bacteria fails Koch's 2nd postulate?
Treponema pallidum
How is Treponema pallidum transmitted (3)?
1) sexual
2) transplacental
3) accidental
What is the most advanced stage of neurosyphillis?
Paresis:

personality, affect, reflexes, eyes, sensorium, intellect, speech.
What is the most florid stage of syphillis?
Secondary stage
What 2 things are used for screening and monitor therapy of syphillis?
1) VDRL

2) RPR
Characteristics of congenital syphillis?
1) rhinitis (snuffles)
2) saddle nose
3) maculopapular rash
4) Hutchinson's teeth - Mulberry molars
5) Saber shins
6) Interstitial keratitis
Which serology tests detect Reagin antibodies of Syphillis?
1) VDRL
2) RPR

Flocculation
What is the lab reagent used to detect syphillis?
cardiolipin
VDRL and RPR
Serology test for syphillis that is SENSITIVE, NON-SPECIFIC.

Non-treponemal tests.

FALSE (+)

Good for SCREENING.

QUANTITATIVE
Which serology tests detect antibodies to surface antigens of spirochetes in syphillis?
1) FTA-ABS

2) MHA-TB
FTA-ABS and MHA-TB
QUALITATIVE test

Treponemal tests

Confirmatory tests

False (+)
How is congenital syphillis diagnosed?
Check for IgM antibodies.

Take mother's blood.

Newborns have IgG from mother.
What are the 2 groups of Phylum Platyhelminthes (flatworms)?
1)Class Cestoda (tapeworms)

2)Class Trematoda (flukes)
Morphology of Class Cestoda (tapeworms)
1) long, ribbon-like
2) dorsally flattened, and segmented
3) NO digestive, respiratory, or vascular systems
4) Hermaphrodites
Each segment of a flatworm is called?
Proglottin
What is the self-contained reproductive unit of a flatworm called?
Proglottin
Summation of proglottids?
Strobila
Name the 3 parts of a tapeworm.
1) Scolex head

2) neck

3) Strobila
What do you call a crown of hooks on a scolex head?
Rostellum
Function of a scolex head?
Used as an attachments to the intestines
Where do proglottids begin to mature?
the neck
Eggs of tapeworms are called?
onchosphere
Onchosphere contain what type of embryos?
hexacanth
What is the definitive host of tapeworms?
humans
Which class are flukes in?
Trematoda
What are the 1st hosts in all flukes?
snails
Swimmers of flukes are called?
cercariae
All Trematodes, EXCEPT Schistosoma are:
1) bilaterally symmetrical
2) leaf-shaped
3) hermaphrodites
4) produce operculated eggs
5) 2 intermediate hosts
Including Shistosoma, Trematodes have the following:
1) Blind digestive system
2) Excretory system has flame cells (primitive kidney)
3) 2 suckers (oral & ventral)
4) Long life span