Microbiology Exam Iii

Front 1

ADCC

Back 1

once antibodies coat the surface of a pathogen, natural killer lymphocytes bind to the Fc regions of the antibody and lyse the target cells with perforin and granzymes

Front 2

adhesins

Back 2

molecules that attach pathogens to their target cells

Front 3

adjuvant

Back 3

increases immune response of "other" while having no immune response elicted itself

Front 4

attenuated virus

Back 4

weakened virus with reduced ability to cause infection and low ability to cause disease, used in "live" vaccines

Front 5

chemokine

Back 5

an immune system cytokine that signals leukocytes to rush to the site of inflammation or infection and activates other leukocytes

Front 6

complement

Back 6

part of innate immunity, antibodies trigger reactions that lead to opsonization by C3b, formation of MAC, inflammation

Front 7

complement protein C3b

Back 7

acts as an opsonin, adheres to bacteria cell walls, starts cascade

Front 8

complement protein C5a

Back 8

releases histamine into bloodstream to cause inflammation

Front 9

CXCR4

Back 9

chemokine receptor in Th-cells for HIV virus, attaches to gp120

Front 10

cytokine

Back 10

proteins secreted by many types of cells that regulate adaptive immune responses

Front 11

GAG

Back 11

group specific antigen, a gene coded by HIV that produces a nonfunctional polyprotein which is cleaved by HIV protease generates nucleocapsid proteins

Front 12

GP120

Back 12

antigenic glycoprotein that is the primary attachment molecule of HIV

Front 13

Hemolysin

Back 13

protein produced by S. aureus and other pathogens that punches holes int he cytoplasmic membranes of red blood cells