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67 Cards in this Set
- Front
- Back
what is an immune response to a innocuous material?
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allergy (asthma)
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Multiple Sclerosis is an example of what type of disease?
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autoimmune disease (anti-self immunity)
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what is a response to a transplanted tissue?
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graft rejection
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___ is a defect in immune resonse
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immunodeficiency
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___ is used to treat immune disease
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immunosuppression
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Immune response:
lysosomes, sebaceous/mucous secretions, stomach acid, commensal organisms, complement proteins, phagocytosis, NK cells are all part of what? |
2nd line of defense (cellular and humoral defenses)
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Immune response:
antibodies, cytokines, T-helper cells, cytotoxic T cells are all part of what? |
third line of defense ( cellular and humoral defenses)
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Immune response:
commensial organisms are what line of defense |
second line of defense
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Immune response:
cytokines are what line of defense |
third line of defense
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Immune response:
phagocytosis are what line of defense |
second line of defense
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Immune response:
NK cells are what line of defense |
second line of defense
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Immune response:
cytotoxic T cells are what line of defense |
third line of defense
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Immune response:
antibodies are what line of defense |
third line of defense
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Two types of immunity:
what are the 4 things under Innate (natural) immunity? |
anotomical defenses
inflammation fever phagocytic barriers |
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two types of immunity:
WHAT ARE THE 3 THINGS under acquired (adaptive) immunity? |
specificity
tolerance memory |
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what type of immunity is considered natural immunity?
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innate immunity
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what type of immunity is considered adaptive immunity?
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acquired immunity
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fever is considered innate(natural) or acquired (adaptive) immunity?
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innate (natural)
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t/f
innate (natural) immunity is antigen specific |
false , it isn't antigen specific
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t/f
innate (natural) immunity has memory |
false, t/f
innate (natural) immunity doensn't have memory |
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t/f
innate (natural) immunity is not effective without adaptive immunity |
true
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t/f
innate (natural) immunity is present at birth |
true
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t/f
innate (natural) immunity is not cellular or humoral |
false,
innate (natural) immunity is cellular and humoral |
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t/f
adaptive immunity is antigen specific |
true
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t/f
adaptive immunity is has memory |
true
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____=cells, proteins and supporting systems that kill or inactivate invaders (such as bacteria, viruses, fungi, and protozoa) reacts to cheicals and allergens, and monitor every cell in the body for cancer
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immune system
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what is responsibe for the immune system rejecting transplanted tissues
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MHC on the tissue
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___ is a substance that illicits an immune response
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antigen
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t/f
antigens have a size restriction of >10,000 MW |
true
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t/f
immune system does not detect an antigen regardless of it's source |
false, immune system detects antigen regardless of its source
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infected and cancer cells express identifiable antigens on their ___
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surface
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what are key components of the immune system? (3)
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blood, lymph, lymph system
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what are 2 immune system proteins?
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interferons and complement
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Lymphoid Organs:
what are the 2 primary organs? |
bone marrow and thymus
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Lymphoid organs:
what are the 5 secondary organs? |
spleen
tonsils apendix lymphnodes MALT (collects Ag from the respiratory, GI tract) |
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What is MALT and what does it do?
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it is a secondary organ of the lymph system that collects Ag from the GI and Respiratory tract
M.ucosa A.ssociated L.ymphatic T.issue |
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What does SALT stand for ?
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S.kin A.ssociated L.ymphatic T.issue
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What allows antigens to enter the intestinal system?
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Peyer's patch
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All microorganisms are made up of 4 polymers which are:
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proteins, carbs, lipids, nucleic acids
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out of the 4 polymers that make up microorganisms, (proteins, carbs, lipids, nucleic acids) which are most reactive to antigenic compounds
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proteins
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T/F
All cells and liquids can pass through and into blood and lymph vessels and move between these two systems |
false, all cells and liquids except RBC
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where do formed elements come from?
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bone marrow
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___ has both myloid and lymphoid origins
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Leukocytes
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What things fall under leukocytes?
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T-cells and B-cells
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What activate B cells and macrophages?
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T-helper cells
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What do B Cells produce?
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antibodies that when activated become plasma cells
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that two things to T cells produce?
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cytotoxic T lymphocytes (which kill virus infected cells)
T-helper cells (which activate macrophages and B cells , which in turn make antibodies which turn into plasma cells |
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immunity--> innate (natural)and adaptive
innate is 1st, 2nd 3rd 1st and 2nd 1st and 3rd 2nd and 3rd line of defense |
1st and 2nd line of defense (physical)
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immunity--> aquired (adaptive) immunity is
1st, 2nd 3rd 1st and 2nd 1st and 3rd 2nd and 3rd line of defense |
third line of defense
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mucous membranes of the respiratory, digestive, urinary, and reproductive systems are considered ___line of defense
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first line of defense
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what are the two major layers of the skin?
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epidermis and dermis
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which layer of the skin contains protein fibers called collagen ?
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dermis
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what is the purpose of SALT?
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an early warning system that recognizes bacteria and warns immune system
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what gives strength and pliability to resist abrasions that could introduce microorganisms?
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collagen
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what line all body cavities to the outside environment?
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mucose membranes
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what is the largest organ in the body?
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skin
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what layer of the skin is constantly shedding dead skin cells which removes attached germs?
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epidermis
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what is the difference in the epithelial cells of the surface and of the mucous membrane?
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the epithelial cells of the mucous membrane are living
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Microbial Antagonism
____ compete with potential pathogens by: limiting pathogen growth, consuming and rubbing pathogens of nutrients manipulating the enviroment (pH) help stimulate the body's second line of defense promote overall health by providing vitamins to host |
normal flora
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what operates when pathogens succeed in penetrating the skin or mucous membranes?
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second line of defenses
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What is the thin, outer covering of the mucous membranes?
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epithelium
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what are some of the ways normal flora competes with potential pathogens?
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limiting pathogen growth,
consuming and rubbing pathogens of nutrients manipulating the enviroment (pH) help stimulate the body's second line of defense promote overall health by providing vitamins to host |
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the second line of defense in a nonspecific defense
t/f |
true
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second line of defense:
phagocytosis, extracellular killing by leukocytes, nonspecific chemical defenses, inflammation, fever are all components that are contained or originate where? |
the blood
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Serum contains complement proteins and antibodies
t/f |
false, plasma contains complement proteins and antibodies
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what are the cells and cell fragments called in plasma?
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formed elements
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what line of defense composes cells, antimicrobial chemicals, and processes but no phyical barriers?
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second line of defense
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