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67 Cards in this Set

  • Front
  • Back
what is an immune response to a innocuous material?
allergy (asthma)
Multiple Sclerosis is an example of what type of disease?
autoimmune disease (anti-self immunity)
what is a response to a transplanted tissue?
graft rejection
___ is a defect in immune resonse
immunodeficiency
___ is used to treat immune disease
immunosuppression
Immune response:

lysosomes, sebaceous/mucous secretions, stomach acid, commensal organisms, complement proteins, phagocytosis, NK cells are all part of what?
2nd line of defense (cellular and humoral defenses)
Immune response:

antibodies, cytokines, T-helper cells, cytotoxic T cells are all part of what?
third line of defense ( cellular and humoral defenses)
Immune response:

commensial organisms are what line of defense
second line of defense
Immune response:

cytokines are what line of defense
third line of defense
Immune response:

phagocytosis are what line of defense
second line of defense
Immune response:

NK cells are what line of defense
second line of defense
Immune response:

cytotoxic T cells are what line of defense
third line of defense
Immune response:

antibodies are what line of defense
third line of defense
Two types of immunity:

what are the 4 things under Innate (natural) immunity?
anotomical defenses
inflammation
fever
phagocytic barriers
two types of immunity:

WHAT ARE THE 3 THINGS under acquired (adaptive) immunity?
specificity
tolerance
memory
what type of immunity is considered natural immunity?
innate immunity
what type of immunity is considered adaptive immunity?
acquired immunity
fever is considered innate(natural) or acquired (adaptive) immunity?
innate (natural)
t/f

innate (natural) immunity is antigen specific
false , it isn't antigen specific
t/f

innate (natural) immunity has memory
false, t/f

innate (natural) immunity doensn't have memory
t/f

innate (natural) immunity is not effective without adaptive immunity
true
t/f

innate (natural) immunity is present at birth
true
t/f

innate (natural) immunity is not cellular or humoral
false,

innate (natural) immunity is cellular and humoral
t/f

adaptive immunity is antigen specific
true
t/f

adaptive immunity is has memory
true
____=cells, proteins and supporting systems that kill or inactivate invaders (such as bacteria, viruses, fungi, and protozoa) reacts to cheicals and allergens, and monitor every cell in the body for cancer
immune system
what is responsibe for the immune system rejecting transplanted tissues
MHC on the tissue
___ is a substance that illicits an immune response
antigen
t/f

antigens have a size restriction of >10,000 MW
true
t/f

immune system does not detect an antigen regardless of it's source
false, immune system detects antigen regardless of its source
infected and cancer cells express identifiable antigens on their ___
surface
what are key components of the immune system? (3)
blood, lymph, lymph system
what are 2 immune system proteins?
interferons and complement
Lymphoid Organs:
what are the 2 primary organs?
bone marrow and thymus
Lymphoid organs:
what are the 5 secondary organs?
spleen
tonsils
apendix
lymphnodes
MALT (collects Ag from the respiratory, GI tract)
What is MALT and what does it do?
it is a secondary organ of the lymph system that collects Ag from the GI and Respiratory tract

M.ucosa A.ssociated L.ymphatic T.issue
What does SALT stand for ?
S.kin A.ssociated L.ymphatic T.issue
What allows antigens to enter the intestinal system?
Peyer's patch
All microorganisms are made up of 4 polymers which are:
proteins, carbs, lipids, nucleic acids
out of the 4 polymers that make up microorganisms, (proteins, carbs, lipids, nucleic acids) which are most reactive to antigenic compounds
proteins
T/F

All cells and liquids can pass through and into blood and lymph vessels and move between these two systems
false, all cells and liquids except RBC
where do formed elements come from?
bone marrow
___ has both myloid and lymphoid origins
Leukocytes
What things fall under leukocytes?
T-cells and B-cells
What activate B cells and macrophages?
T-helper cells
What do B Cells produce?
antibodies that when activated become plasma cells
that two things to T cells produce?
cytotoxic T lymphocytes (which kill virus infected cells)

T-helper cells (which activate macrophages and B cells , which in turn make antibodies which turn into plasma cells
immunity--> innate (natural)and adaptive

innate is
1st,
2nd
3rd
1st and 2nd
1st and 3rd
2nd and 3rd
line of defense
1st and 2nd line of defense (physical)
immunity--> aquired (adaptive) immunity is
1st,
2nd
3rd
1st and 2nd
1st and 3rd
2nd and 3rd
line of defense
third line of defense
mucous membranes of the respiratory, digestive, urinary, and reproductive systems are considered ___line of defense
first line of defense
what are the two major layers of the skin?
epidermis and dermis
which layer of the skin contains protein fibers called collagen ?
dermis
what is the purpose of SALT?
an early warning system that recognizes bacteria and warns immune system
what gives strength and pliability to resist abrasions that could introduce microorganisms?
collagen
what line all body cavities to the outside environment?
mucose membranes
what is the largest organ in the body?
skin
what layer of the skin is constantly shedding dead skin cells which removes attached germs?
epidermis
what is the difference in the epithelial cells of the surface and of the mucous membrane?
the epithelial cells of the mucous membrane are living
Microbial Antagonism

____ compete with potential pathogens by:
limiting pathogen growth,
consuming and rubbing pathogens of nutrients
manipulating the enviroment (pH)
help stimulate the body's second line of defense
promote overall health by providing vitamins to host
normal flora
what operates when pathogens succeed in penetrating the skin or mucous membranes?
second line of defenses
What is the thin, outer covering of the mucous membranes?
epithelium
what are some of the ways normal flora competes with potential pathogens?
limiting pathogen growth,
consuming and rubbing pathogens of nutrients
manipulating the enviroment (pH)
help stimulate the body's second line of defense
promote overall health by providing vitamins to host
the second line of defense in a nonspecific defense

t/f
true
second line of defense:

phagocytosis, extracellular killing by leukocytes, nonspecific chemical defenses, inflammation, fever are all components that are contained or originate where?
the blood
Serum contains complement proteins and antibodies

t/f
false, plasma contains complement proteins and antibodies
what are the cells and cell fragments called in plasma?
formed elements
what line of defense composes cells, antimicrobial chemicals, and processes but no phyical barriers?
second line of defense