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18 Cards in this Set

  • Front
  • Back
What are common presenting symptoms?
1) watery diarrhea less than 2 weeks
2) low-grade fever
3) nausea
4) anorexia with weight loss
What is seen on physical exam?
1) patient is cachectic
2) mild diffuse abdominal tenderness
3) slightly elevated temp
What is the most common GI manifestation with AIDS and cryptospordosis?
protracted and repeated severe watery diarrhea
Why would you exam stool for white blood cells?
to determine inflammatory enteritis
When would you measure clostridium difficile toxin?
someone that was taking heavy antibiotics
what do the oocysts stain with?
modified acid fast stain
What are the defining characteristics of C parvum?
intracellular coccidian protozoa. Its oocysts are acid fast and stain red with modified carbol fuchsin
Each oocyst contains how many sporozoites?
4
What groups are at risk?
AIDS and renal or bone marrow transplant patients and gay men
What is a unique life cycle feature of this organism?
it undergoes sexual reproduction within the human host to regenerate infective oocysts
How is it spread?
fecal oral, found in water
What form adheres to the small intestine epithelial cells?
motile sporozoites
what is the most heavily infiltrated site?
jejunum
Where does their entire life cycle occur?
amongst the microvilli
How do they disrupt host cells?
by enveloping themselves in the host cell membrane "intracellular but extracytoplasmic"
How does diarrhea occur?
when intestinal absorption is disrupted
where does the asexual cycle occur?
when the parasites enter cells
What is it treated with?
no reliable therapy try with paromomycin, nitazoxanide and azithromycin. Rehydration is only necessary in non immunocompromised people