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18 Cards in this Set
- Front
- Back
What are common presenting symptoms?
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1) watery diarrhea less than 2 weeks
2) low-grade fever 3) nausea 4) anorexia with weight loss |
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What is seen on physical exam?
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1) patient is cachectic
2) mild diffuse abdominal tenderness 3) slightly elevated temp |
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What is the most common GI manifestation with AIDS and cryptospordosis?
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protracted and repeated severe watery diarrhea
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Why would you exam stool for white blood cells?
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to determine inflammatory enteritis
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When would you measure clostridium difficile toxin?
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someone that was taking heavy antibiotics
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what do the oocysts stain with?
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modified acid fast stain
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What are the defining characteristics of C parvum?
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intracellular coccidian protozoa. Its oocysts are acid fast and stain red with modified carbol fuchsin
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Each oocyst contains how many sporozoites?
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4
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What groups are at risk?
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AIDS and renal or bone marrow transplant patients and gay men
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What is a unique life cycle feature of this organism?
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it undergoes sexual reproduction within the human host to regenerate infective oocysts
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How is it spread?
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fecal oral, found in water
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What form adheres to the small intestine epithelial cells?
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motile sporozoites
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what is the most heavily infiltrated site?
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jejunum
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Where does their entire life cycle occur?
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amongst the microvilli
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How do they disrupt host cells?
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by enveloping themselves in the host cell membrane "intracellular but extracytoplasmic"
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How does diarrhea occur?
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when intestinal absorption is disrupted
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where does the asexual cycle occur?
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when the parasites enter cells
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What is it treated with?
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no reliable therapy try with paromomycin, nitazoxanide and azithromycin. Rehydration is only necessary in non immunocompromised people
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