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9 Cards in this Set
- Front
- Back
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Important species from Family Chlamydia |
C. Trachomatis C. Psittaci C. Pneuomoniae |
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C. Trachomatis characteristic complications |
Urogenital infections Trachoma Conjunctivitis Pneumonia Lymphogranuloma venerium (LGV) |
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C. Psittaci |
Pneumonia (psittacosis) |
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C. Pneumoniae |
Bronchitis Sinusitis Pneumonia |
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Chlamydiacae |
Small obligate intracellular parasites Contain DNA, RNA and ribosomes Inner and outer membrane LPS but no peptidoglycan Energy parasites--can't make ATP |
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Chlamydia physiology (EB) |
Small 0.3-0.4ųm Extracellular form Rigid outer membrane: Disulfide linked protein Resistant to harsh conditions Non-replicating, non-metabolically active form Infectious form: bind to columnar epithelial cells (macrophages) |
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Chlamydia physiology (RB) |
Larger 0.8-1ųm Intracellular form Fragile membrane: fewer Disulfide bonds Metabolically active form Replicating form Non-infectious |
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Developmental cycle of Chlamydia |
EB binds to host cells -epithelial -macrophages Internalisation: -endocytosis -phagocytosis Inhibition of lysosomal phagosomal fusion Reorganisation into RB: breakdown of Disulfide bonds Growth of RB Reorganisation into EB Inclusion bodies Release of EB |
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Release of Elementary bodies for each species |
Lysis- C. Psittaci Extrusion- C. Trachomatis C. Pneuomoniae |
