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13 Cards in this Set

  • Front
  • Back

Sterilization

refers to the removal ordestruction of all microbes

Microbistatic

Prohibits the growth of microorganisms. In the presence of microbiostatics, the microorganisms eventually die due to lack of reproduction

Antisepsis

When chemical is used on skin or other living tissue

Microbicdial

Agent kills microorganisms

Disinfection

Use of physical or chemical agents to kill microorganisms on inanimate objects

degerming

the removal of microbes from a surface byscrubbing

Microbial death

Permanent loss of reproductive capability in microorganisms

Sanitization

process of disinfecting places andutensils used by the public to reduce the number of pathogenicmicrobes to meet accepted public health standards

pasteurization

use of heat to kill pathogens andreduce the number of spoilage microorganisms in food andbeverages

antibiotic

antimicrobial chemicals producednaturally by microorganisms

Mechanisms of resistance

1: cells may produce an enzyme that destroys ordeactivates the drug.


2: slow or prevent the entry of thedrug into the cell


3: alter the target of the drug so that thedrug either cannot attach to it or binds it less effectively


4: Alter their metabolic chemistry, or theymay abandon the sensitive metabolic step altogether


5: Pump the antimicrobial out of the cellbefore the drug can act


6: Bacteria within biofilms resist antimicrobials more effectivelythan free-living cells


7: protecting the target of an antimicrobial drug

Selective toxicity vs. toxicity

selective toxicity antimicrobial agents are more toxic topathogens than to the patient

probiotics

Beneficial Microbes