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37 Cards in this Set

  • Front
  • Back

Microbiology

-The study of Microorganisms, or Microbes.

Microorganisms

-Organisms that are microscopic, or require magnification to be adequately observed or studied.

Microorganisms are Ubiquitous

-Everywhere and being, or seeming to be, everywhere at the same time.

Major groups of microorganisms

-Bacteria, Viruses, Fungi, Protozoa, Algae, and Helminths (Parasitic Worms).

Prokaryote

-Microscopic, unicellular organism, lack nuclei, and membrane bound organelles.



Eukaryote

-Unicellular and multicellular, nucleus and membrane bound organelles

Bacteria

-Prokaryotic


-Diverse Metabolism


-Most Numerous on the Planet

Archaea

-Exist in Extreme Environments


-Prokaryotic


-Genetically similar to Eukaryotes

Viruses

-Eukaryotic


-Single-Celled


-Infects Genes - DNA & RNA


-Needs a host to be active


-Non-living


-Destroy T-Cells

Fungi

-Eukaryotic


-Can be either Multicellular or Unicellular


-May or may not have more than 1 nucleus



Protozoa

-Eukaryotic


-Unicellular


-Move by using Cilla or Flagella


-Found in Soil/Water



Algae

-Eukaryotes


-Photosynthesize


-Unicellular



Helminths

-Eukaryotes


-Kingdom of "Animalia" -> Embryonic Developement


-We ingest eggs or cysts and then the worm forms

Micron

- 1 micrometer


- 1/ 1 millionth meter = 1/1,000,000 meters


- 1/1000 millimeter

Nanometer

- 1000x smaller than a micron


- 1/1 billionth meter = 1/1,000,000,000 meters


- Size range of Viruses, Proteins, and DNA

Selman Wakesman

- Isolated 22 new compounds made bysoil microbes including streptomycin,the first antibiotic effective against tuberculosis.


- Taught at Rutgers for 40 years


Robert Hooke

- Reported that living things are composed of little boxes of cells


- Invented the first microscope


- Labeled the first cell

Rudolf Virchow

- Cells come from pre-existing cells


- All cells have a mommy and daddy


(AKA Parents)

Antoni Van Leeuwenhoek

- Described live microorganisms that he observed in teeth scrapings, etc.


- First to see Dust-mites, sperm, etc.

Francisco Redi

- Filled 6 jars with decaying meat:


maggots came about for the ones with the cheese cloth and Maggots came to the open jar

Louis Pasteur

- Demonstrated that Microorganisms are present in air


- Disproved Spontaneous generation of microbes


- S-Shaped flask kept microbes out but let air in


- Developed First Rabies Vaccine


- Discovered Pasteurization, for which he is named for, which is heating liquids to kill microbes.

Joseph Lister

- Founder of Antiseptic Medicine


- Made people wash hands in it before surgery

Robert Koch

- Proved that a particular disease was caused by a particular microbe


- Disease Theory for Medicine


- First to prove germ theory of disease for particular illness


- He discovered Anthrax and TB

Edward Jenner

- Inoculated a person with cowpox, the person was then protected from cowpox


- Basically made the first Vaccination

Vaccination

- Derived from vacca for cow


- This protection is called an immunity

Chemotherapy

- Treatment with Chemicals


- Chemotherapeuticagents used to treat infectious disease can be synthetic drugs or antibiotics


- Antibioticsare chemicals produced by bacteria and fungi that inhibit or kill othermicrobes.

Quinine

- A chemical derived from a specific tree bark that has been used to treat malaria

Paul Eldrich

- Developed a synthetic arsenic drug used to treat syphilis

Alexander Fleming

- Discovered the first Antibiotic


- Observed that the Penicilliumfungus made an antibiotic, penicillin, that killed S. aureus.


-

Immunology

- The study of immunity. Vaccines and interferonsare being investigated to prevent and cure viral diseases

Rebecca Lancefield

- Proposed the use of immunology to identify some bacteriaaccording to type

Elie Metchnikoff

- Discovered the role of white blood cells in fighting infection, first in starfish.

Recombinant DNA

- DNAmade from twodifferent sources. In the 1960s, Paul Berginserted animal DNA into bacterial DNA and the bacteriaproduced an animal protein.

Genetic Engineering

- Involves microbial genetics and molecularbiology. (Recombinant DNA Technology)

Oswald Avery, Colin MacLeod, and Maclyn McCarty

- Showed that DNA was the "stuff of genes" using microbes

JimWatson and Francis Crick

- "Puzzled out" the structure of DNA

Nathans, Smith, Arber

- Developedways to cut and snip DNA with “stickyends” forgenetic engineering: the engineer’sscizzors!