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24 Cards in this Set
- Front
- Back
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B lactamase clevage of B lactam ring is the mechanism of resistance for what antibiotics?
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penicillins/cepalosporins
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Modification via acetylation, adenylation, or phosporylation is the mechanism of resistance for what antibiotics?
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aminoglycosides
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Terminal D alla of cell wall component with D LAC and decreased affinity is the mechanism of resistance for what antibiotics?
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vancomycin
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Modification via acetylaion is the mechanism of resistance for what antibiotics?
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choloramphenicol
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Methylation of rRNA near drugs ribosome-binding site is the mechanism of resistance for what antibiotics?
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macrolides
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Decrease uptake and increased transport out of cell is the mechanism of resistance for what antibiotics?
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tetracyclin
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Altered enzyme (bacterial dihydropteroate synthetase), decrease uptake, or increase PABA synthesis is the mechanism of resistance for what antibiotics?
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sulfonamides
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antimirobial prophylaxis - meningococcal
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Riampin (drug of choice)
Minocyclin |
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antimirobial prophylaxis - gonorrhea
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ceftriaxone
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antimirobial prophylaxis - syphillis
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Benzathine penicillin G
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antimirobial prophylaxis - history recurrent UTI's
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TMP-SMX
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antimirobial prophylaxis - pneumocytis carinii pneumonia
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TMP-SMX (drug of choice), aerosolized pentamidine
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antimirobial prophylaxis - endocarditis with surgical or dental procedures
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Penicillins
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what drugs avoid during preg?
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SAFE Moms Take Really Good Care -Sulfonamides, Aminoglycosides, Fluoroquinolone, Erythromycin, Metronidazole, Tetracyclins, Ribavirin, Griseoulvin, Chloamphenicol
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what birth defect sulfonamides cause?
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kernicterus
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what birth defect aminoglycosides cause?
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ototoxicity
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what birth defect Fluoroquinolones cause?
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Cartilage damage
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what birth defect erthyromycin cause?
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acute cholestatic hepatitis in mom
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what birth defect does clarithromycin cause?
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embryotoxic
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what birth defect metronidazole cause?
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mutagenesis
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what birth defect tetracylines cause?
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discolored teeth, inhibition of bone growth
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what birth defect ribavirin (antiviral) cause?
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teratogenic
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what birth defect griseofulvin (antifungal) cause?
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teratogenic
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what birth defect choloramphenicol cause?
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gray baby
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