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21 Cards in this Set
- Front
- Back
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Bacteriostatic
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stop replication but doesnt kill the bacteria
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Bacteriocidal
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Kills the bacteria
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Areas in the bacteria that the antibiotic might alter
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Cell wall, cell membrane, DNA/RNA, protein synthesis, folic acid
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When was penicilin discovered?
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1929
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Antibiotics that break down cell wall
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Beta lactam antibiotics
penillin, vancomyosin, cephlosporins |
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Antibiotics that change DNA/RNA synthesis
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floroquinolones
Affects DNA girase (unwinding) |
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Thing that penicillin, cephlosporins and vancomycin all have
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Beta-Lactam ring
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Form peptidoglycan layer
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NAM and NAG
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Cell wall active agents will be effective on...
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gram + but not gram -
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Beta-Lactam Ring antibiotics (Penicillin, Cephalosporins, vancomycin) will not be effective against
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Gram -
Capsules Intracellular organisms Fungi Viruses Protozoa |
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What is augmentin a mixture of?
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amoxicillin and clavulaunic acid
Clavulonic acid fights beta lactamases |
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What percentage of pts that are allergic to penicillin will react to cephalosporins?
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about 10%
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PBP
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penicillin binding proteins
on surface of bacterial cell- allows it to gain access to the cell |
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Antibiotics that interfere with 30S
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Aminoglycosides
Tetracyclines |
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Antibiotics that interfere with 50S ribosomes
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Macrolides
Clinamycin |
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Aminoglycosides
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Streptomycin, gentamycin
bacteriocidal, serious infections blocks initation complex ototoxic- hearing loss nephrotoxic |
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Tetracyclines
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Dont give to kids/pregnant women because of teeth staining
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Macrolides
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Erythromycin, Z-pack
bacteriostatic |
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Inhibition of Nucleic Acid syntheis
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Quinolones- block DNA girase
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Folate blockers
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Trimethoprim
Sulfonamides |
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Reserved to tx of microplasma
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Tetracyclines
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