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25 Cards in this Set
- Front
- Back
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Streptococcus pyogenes (description/ tests)
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throat culture
gram + , catalase -, Group A strep cocci in chains,increased ASO titer susceptible to bacitracin, presence of PYR direct antigen test is highly specific and not that sensitive. |
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S. pyogenes (sequelae)
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pharyngitis/impetigo(honey-crusted)
rheumatic fever and glomerulonephritis Toxin release--> scarlet fever, TSS |
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S. pyogenes (clinical features)
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honey crusted lesions,
pharyngitis, pustular rash, smoky colored urine |
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S. pyogenes (treatment)
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penicillin G, if resistant, erythromycin
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S.pyogenes (virulence)
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streptokinase, M protein, hyaluronidase, DNAase
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Chlamydia psittaci (description and tests)
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obligate intracellular.
not gram + OR gram - iodine stain - for intracellular inclusion Giemsa stain + for intracell inclusion |
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Chlamydia psittaci (virulence)
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carried by birds, spread by feces.
life cycle has 2 forms: Extracell Elementary body, and intra reticular. EB is infective, RB blocks phagosome/lysosome fusion so you get an intracellular inclusion body. replicate WITHIN inclusion body. |
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Chlamydia psittaci (sequelae)
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psittacosis (atypical pneumo)
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Chlamydia psittaci (clinical features/buzz words)
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headache, fever, dry cough
bilateral rales and splenomegaly patchy pneumonitis on CXR pet owner/vets |
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Chlamydia psittaci (treatment)
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antibodies that enter cells, doxycycline, tetracycline.
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Chlamydia trachomatis (description/tests)
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non gram+ or gram -
obligate intracellular iodine stain for inclusion body + because inclusion contains glycogen giemsa stain + culture |
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Chlamydia trachomatis (virulence)
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Serovars, Elementary body = infective, Reticular body blocks phagosome-lysosomal fusion, intracellular incluson body.
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Chlamydia trachomatis (sequelae)
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adhesions around liver capsule (Fitz-Hugh-Curtis)
serovars D-K = damages epi, PID in females, Reiters syndrome in males with arthritis neonates - pneumo and conjunctivitis Serovars A-C = trachoma, corneal damage and blindness Serovars L1-L3= STI, PAINLESS ulceration |
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Chlamydia trachomatis (clinical features/buzzwords)
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vaginal discharge/urethral discharge, RUQ, lots of PMNs in discharge but no organisms.
"Gay Bowel Syndrome" = proctolitis often silent infections in men. |
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Chlamydia trachomatis (treatment)
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azithro
tetracycline erythromycin for neonates prophylactic erythro eyedrops for babies |
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Chlamydia pneumoniae (description/tests)
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neither gram + or gram -
obligate intracellular giemsa stain + for inclusion bodies |
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Chlamydia pneumoniae (virulence)
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Elementary Body infective, Reticular body blocks phagosomal-lysosomal fusion = inclusion body
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Chlamydia pneumoniae (sequelae)
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atypical pneumo
local pulmonary edema, necrosis, hemorrhage |
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Chlamydia pneumoniae (clinical features/buzzwords)
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dry cough, fever, sore throat.
CXR = diffuse interstitial infiltrate sputum shows no organisms but lots of PMNs. young adult infection |
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Chlamydia pneumoniae (treatment)
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antibiotics that enter cells, doxy, tetracycline.
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Corynebacterium diphtheriae (description/tests)
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gram+ bacilli, non spore-forming, non-motile
cultured on tellurite media (Tinsdale) aerobic chinese letter |
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Corynebacterium diphtheriae (virulence)
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diphtheria toxin = AB toxin that ribosylates EF2 and prevent protein synth in all cells
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Corynebacterium diphtheriae (sequelae)
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airway obstruction,
myocarditis, polyneuritis, arrhythmia, cranial and peripheral nerve palsy. |
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Corynebacterium diphtheriae (clinical features/buzzwords)
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sore throat, grey film on oropharynx,
difficulty breathing/swallowing slight paralysis of tongue, ST-T wave change chinese letter |
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Corynebacterium diphtheriae (treatment)
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DTaP = prophylactic
txt = antitoxin (horse serum), penicillin/erythro, DTaP booster |
