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18 Cards in this Set

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Immunization employs the use of Bacillus Calmette Guerin (BCG), one of the only live attenuated bacterial vaccines available.
Mycobacterium TB
Atypical Mycobacteria causing skin granulomas, called swimming pool or fish tank granulomas which occur at the site of abrasions.
Mycobacterium Marinum
Atypical Mycobacteria causing Pulmonary TB
Mycobacterium Kansii
Atypical Mycobacteria causing cerviacal llymphadenitis primarily in children called scrufula
Mycobacterium Scrofulaceum
One of the most common opportunistic bacterial infections in AIDS patients.
Known as the harbringer of death as it only strikes when Helper T's are virtually nonexistent.
Mycobacterium Avium Complex (MAC)
Presents similarly to TB and is acquired from soil, birds, or other animals
The test for TB.
PPD, purified protein derivative
Detect a delayed type hypersensitivity rxn.
Rule of 5's
5-Immunocompromised
10-normal positive
15-
Infection can result in the involvement of vertebrae (Pott's Disease) with spread to form a psoas abscess and, in immunocompromised patients, overwhelming miliary dissemination
Mycobacterium TB

Although rare in the US, incidences of infections are increasing in immunocompromised patient and urban populations, with high incidence of multidrug-rsistant strains.
The classic presentation of infection with this organism includes fever, night sweats, fatigue, and weight loss.
Mycobacterium TB

Presents similarly to other granulomatous infections such as histoplasmosis or coccidioidomycosis.
Primary infection results in subpleural parenchymal lesions and enlarged caseous lymph nodes (Gohn complex) and reactivation can result in cavitary lesions in the upper lung lobes
Myobacterium TB

Dx: confirmed by finding Acid-Fast bacilli in the sputum or in cultures that take several weeks to grow.
Infection results in the destruction of skin and cartilage, resulting in a leonine facies and limb deformities.
Mycobacterium Leprae

Hansen disease, presents as a spectrum between 2 extremes, from Tuberculoid leprosy associated with a good prognosis to Lepromatous Leprosy, in which numerous acid-fast bacilli are stuffed in macrophages = Lepra Cells
Infection results in the destruction of peripheral nerves, resulting in anesthesia followed by atrophy and autoamputation.
Mycobacterium Leprae
This acid fast bacilli has a long generation time, approximately 13 days, and cannot be cultivated in the laboratory
Cause of Scrofula - lymph node infection
Mycobacterium TB
Cause of Sterile Pyuria - presence of red and white blood cells in the urine but no bacteria via Grams stain
Mycobacterium TB
Associated with Pott's Disease
Destruction of thoracic vertebrae
Mycobacterium TB
Causes Miliary TB disseminated throughout organ systems and Brain granulomas.
Mycobacterium TB
Affects:
Skin: Leonine Faces, saddle nose deformity
Nerves:glove/stocking numbness
Eyes:anterior blindness
Testes:infertility
Mycobacterium Leprae

Lepromatous Leprosy LL
Impossible to grow in culture; only grows on footpads of mice, armadillos and monkeys.
Grows best on cool body parts.
Mycobacterium Leprae
Tx: Dapsone
The Lepromin skin test is similar to what and what is it used for?
Similar to PPD.
Measures the ability of the host to mount a delayed hypersensitivity reaction against antigens of Mycobacterium Leprae
NOT DIAGNOSTIC