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13 Cards in this Set

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Major cause of ABE (fast) especially in IV drug users.(Rt side, tricuspid - causes damaged to healthy tissue)

Exotoxin:Antibiotics don't help
Enterotoxin - Gastroenteritis
TSST-1 - palms soles desquamate
Exfolatin - Sacalded skin syndrome - fine sheets of peeling skin- neonates umbilical cord

Organ invasion:
Sepsis
Pneumonia - CAP + cavitations
Meningitis
Osteomyelitis - hematogenous 12yr old boys
ABE - R - lung, L- brain
Septic arthritis
Skin infections - Impetigo, cellulitis, folliculits
UTI

MRSA
Staph Aureus (gold)
Coagulase + = Activates prothrombin causing clotting

Tx: Group II penicillin
MRSA:IV Vancomycin, Daptomycin
Second leading cause of UTI in sexually active women
Staph Saphrophyticus
Coagulase -

Ferments mannitol
Resistant to novobiocin

Tx:Penn G,V
Part of the normal flora of skin. Blood culture contaminant,draw @ 2 sites.
Nosocomial infections
Prosthetics (endocarditis)
UTI
Sepsis (IV, Cathethers)
Staph Epidermidis
Coagulase -

Does not ferment mannitol

Tx:Vancomycin
Alpha hemolytic, Optochin Sensitive

Lancet shaped diplococci found in rusty brown sputum.
Causes >90% cases of lobar pneumonia.
Most common cause of bacterial meningitis in adults and otitis media in kids.

Pneumonia
Meningitis
Sepsis

Otitis Media (Kids)
Strep Pneumonia (pneumococcus)

Pneumococcus is to Parents what group B is for Babies

Polysaccharide capsule - 84
Dx: Quelling Rx, Optochin sens
Tx:Penn G, Erythromycin, Ceftriaxone
Prophylaxis: Vaccine 23 ag.
Elderly, asplenic, sickle cell, immunocomp.
Adults: Pneumovax
Kids: heptavalent - 6,9,14,19,23
Alpha hemolytic, Optochin Resistant

Normally found in GI, nasopharynx and gingiva. Leading cause of SBE.

Dental infections - cavities
SBE - previously damaged, slow
Abscesses - organs, growth in blood, order CT with contrast
Strep Viridans (Green)

Salivarius, Sanguis, Mitis, Intermedius (abcesses), Mutans (dental)

Tx:Penn G
Beta hemolytic, Bacitracin sensitive

Invasion/Exotoxin Release:
Strep pharyngitis - Penn G,V
Skin infection - impetigo, cellulitis, folliculits, necrotizing fasciitis/myositis
Scarlet Fever - pyrogenic toxin, face sparing, Dick test
TSS

Delayed antibody mediated:
Rheumatic fever (john travolta) - follow pharyngitis (not skin), erythema marginatum, chorea, myocarditis, arthritis
Mitral>aortic valve

Glomerulonephritis
Ag-Ab deposition in glomeular BM complement mediated damage
Occurs 1 wk after pharynx or skin infection
Puffy faced, tea colored urine (hematuria), hypervolemia, high BP in a kid.
Strep Pyogenes -Group A Strep

Dx: DNase B + ASO titers
Tx:
Strep pharyngitis - penn G
Skin infection - Group II penn

Necrotizing/scarlet fever/TSS Penn G + clidamycin (block toxin production)

Rheumatic Fever - prophylactic penicillin (Group III) Amoxicillin - surgery + dental

Glomerulonephritis - Penn G,V
Beta hemolytic, Bacitracin Resistant

25% of women normally carry this vaginally, seen in < 3months of age (neonates)

Sepsis
Pneumonia
Meningitis
Strep Agalactiae -Group B Strep

Tx:Penn G + listeria and E-coli coverage
Gamma hemolytic, Bile Esculin -
Non-Group D Strep
Gamma hemolytic, Bile Esculin +, NaCl +

Normal GI flora

SBE
Biliary tract
UTI
Group D Strep Enterococci
faecalis
faecium

Tx:Ampicillin + Aminoglycoside
Resistant - vancomycin
VRE - pristinomycins
Gamma hemolytic, Bile Esculin +, NaCl -

This bug is associated with colon cancer
Group D Strep
Strep Bovis
Strep Equinus

Bovis in the blood, ca in bowel!
3 Meningitis causing organisms
Group B strep - S. Agalactiae
E-Coli
Listeria

Dx: CSF gram stain culture
Non-specific signs in neonates
Gram + organisms that damage the heart
Strep Pyogenes - RF (R side)
Strep Viridans - SBE
Strep Group D - SBE

Staph Aureus - ABE (L side)
Dx via the quelling Rxn
Strep Pneumoniae
H. Influenzae