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11 Cards in this Set

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Which inflammatory molecules mediate sepsis?
Tumor Necrosis Factor --> Interleukin 1 (p19)
What is the effect of septic shock on the vascular system?
Vasodilation

1. Decreased blood pressure
2. Organ hypoperfusion

(p. 20)
What is the effect of septic shock on the heart?
Myocardial depression

1. Decreased cardiac output
2. Decreased blood pressure
3. Organ hypoperfusion
What is the effect of septic shock on the kidney?
Acute renal failure

1. Decreased urine output
2. Volume overload
3. Accumulation of toxins
What is the effect of septic shock on the lungs?
Adult respiratory distress syndrome

1. Hypoxia
What is the effect of septic shock on the liver?
Hepatic failure

1. Accumulation of metabolic toxin
2. Hepatic encephalopathy
What is the effect of septic shock on the brain?
Encephalopathy

1. Alteration in mental status
What is the effect of septic shock on the coagulation system?
Disseminated intravascular coagulation

1. Clotting
2. Bleeding
What enzyme distinguishes Streptococcus from Staphylococcus?
Strep: gram (+) strips, catalase negative

Staph: gram (+) clusters, catalase positive
What are the patterns and colors of hemolysis of Streptococcus?
Alpha - partial hemolysis, green
Beta - complete hemolysis, clear
Gamma - non-hemolytic
What are 6 major manifestations of rheumatic fever?
1. Fever
2. Myocarditis, followed by valvular heart dz (10-20 years later) (mitral valve > aortic valve)
3. Arthritis (joint swelling)
4. Chorea - 2-3 wks after pharyngitis, aka Sydenham's chorea, or St. Vitus dance
5. Subcutaneous nodules
6. Rash (erythema marginatum) - red margin that spreads from its center