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120 Cards in this Set
- Front
- Back
Name the spore forming Bacteria
|
Bacillus
Clostridium |
|
name the unique molecule associated with spore forming bacteria? (function?)
|
calcium dipicolinate (aids in dehydrating the spore)
|
|
name the non-motile GPR
|
C. Diptheria
Nocardia Clostridium perfingens (ALL other Clostridia are motile) B. Anthracis |
|
Name the acid fast organisms
|
-Mycobacterium
-Nocardia (partially AF) - Cryptosporidium oocysts |
|
Name the major encapsulated organisms (include mnemonic)
|
- Strept. Pneumo
- Klebsiella " " -H. Flu - N. Meningitidis -Cryptococcus Neoformans (Some Killers Have Pretty Nice Capsules) |
|
Describe the B. Anthracis capsule
|
a poly D-glu capsule (IE: the ONLY bacteria with polypeptide capsule)
|
|
name the E. Coli strain associated with a capsule
|
K1 (meningeal strain)
|
|
Describe the group A strept capsule (Composition and function)
Is it immunogenic? |
a hyaluronic acid capsule that plays an antiphagocytic role.
It is NOT immunogenic |
|
Significance of the Salmonella typic capsular antigen
|
it increases virulence
|
|
Name the biofilm producers (and their associated pathology)
|
Staph. epidermidis (cath. related ifns)
Streptococcus mutans (dental caries) |
|
name the most important pigment producing bacteria
what color? |
Psuedomonas aeruginosa
blue-green |
|
Name the pigmnts associated with Pseudomonas
|
-pyocyanin
-fluorescein |
|
Serratia is associated with what color pigment
|
red
|
|
Staph. A. is associated with what color pigment
|
yellow
|
|
C. Diptheriae is associated with what pigment
|
gray-black
|
|
name the general types of pigment producing mycobacterium
associated color? |
photochromagenic and scotochromagnic
yellow and orange |
|
What organism is associated with metachromatic staining?
|
Corynebactrium
|
|
Word association:
Lancet-shaped diplococci |
Strept. Pneumo
|
|
Word association:
Kidney bean-shaped diplococci (associated gram stain) |
Neisseria (gram neg)
|
|
Word association:
Gull wing bacteria |
Campylobacter (although H. Pylori has also been described as such)
|
|
Word association:
bipolar staining |
Yersinia pestis
|
|
Name the virus associated with Negri bodies (location of said bodies)
|
Rabies
(intracytoplasmic) |
|
Name the virus associated with intracytoplasmic acidophilic inclusions
(inclusions AKA) |
Poxviruses
(Guarnieri bodies) |
|
Name the virus associated with Owl eye inclusions
(inclusion location) |
CMV
(intracytoplasmic AND intranuclear) |
|
viruses associated with Syncytia (giant cells)
|
HSV
VZV paramyxovirus RSV HIV |
|
name the microaerophilic bacteria
|
Campylobacter
Helicobacter |
|
Name the key aerobes
|
Mycobacterium (hence their propensity for the lung apex)
Pseudomonas Bacillus |
|
name the less important aerobes
|
Nocardia
C. Diptheriae |
|
name the key anaerobes
|
Actinomyces (in contrast to Nocardia)
Bacteroides Clostridium |
|
name the less important anaerobes
|
Fusobacterium
Prevotella Eubacterium |
|
name the aerotolerant anaerobes
|
Propionibacterium
lactobacillus |
|
All Enterobacteria are Oxidase ______________
|
negative
|
|
All Nesseria are Oxidase ____________
|
positive
|
|
Urease positive organisms(mnemonic)
|
(PUNCH)
Proteus Ureaplasma Cryptococcus Nocardia Helicobacter |
|
name the pathology associated with urease positive UTI's
|
struvite (staghorn) renal caliculi
|
|
Catalase
function |
degrade Hydrogen peroxide
|
|
Most anaerobes are Catalase _________
|
negative
|
|
what is the key to distinguishing Staph. and Strept. organisms?
|
all staph. are catalase positive
all strept. are catalase negative |
|
major pathology associated with Catalase + organisms
|
recurrent and severe ifns in Chronic granulomatous disease
|
|
Name the catalase + organisms
|
Staph
Psuedomonas aeruginosa Candida Aspergillus Enterobacteriaceae |
|
Kevin is _________
|
brilliant, charming and handsome
|
|
name the coagulase positive bacteria
|
Staph A.
Yersinia pestis |
|
bacterial pathogenic factors that are encoded on the chromosome
(mnemonic) |
Chloregan
Endotoxin Shiga Toxin (Chromosome Encoded Shit) |
|
possible locations for bacterial pathogenic factors
|
-bacterial chromosome
-plasmids - bacteriophage chromosome |
|
most bacterial toxins and multiple drug rsistances are encoded on
|
plasmids
|
|
define lysogenic conversion
|
modification of bacterial virulence by the stabl presence of phage DNA in the bacterial cell
|
|
Key examples of plasmid encoded virulence factors/toxins
(mnemonic) |
Salmonella O antigen
Botox Erthrogenic toxin of GAS Dip. Toxin (OBED) |
|
key examples of bacteria that undergo antigenic variation
|
Gonococci (pili)
Borrelia recurrentis Trypanosomoa brucei |
|
mech of Diptheria toxin
|
ADP ribosylation of eEF2 ---> impaired protein synthesis
|
|
mech of Tetanus toxin
|
inhibition of release of inhibitory GABA and Glycine leading to tetany
|
|
mech of Botox
|
interaction with synaptobrevin impairs ACH release
|
|
Cholera toxin mech
|
ADP ribosylation of Gs leads to elevated cAMP and subsequent secretion
|
|
ETEC toxin mech
|
ADP ribosylation of Gs leads to elevated cAMP and subsequent secretion
|
|
name the C. Diff. toxins
|
Toxins A and B
|
|
C. Diff. toxin mechs
|
inhibition of protein synthesis and loss of intracellular K+
|
|
toxins stable at 60 degrees C
|
Staph A. enterotoxin
ST toxin of E. Coli Yersinia enterocolitica toxin |
|
toxins stabl at 100 degrees C
|
LPS
|
|
name the important Pseudomonas exotoxins
|
exotoxin A and S
|
|
Pseudomonas exotoxin mech
|
ADP-ribosylation of eEF2
|
|
Pertussis toxin mech.
|
ADP-ribosylation of Gi leading to increased cAMP
|
|
what organism is classically associated with a "slime layer" (function)
|
Psuedomonas
(anti-phagocytic) |
|
organism that produces M protein (function)
|
GAS
(anti-phagocytic) |
|
organism that produces A protein (function)
|
Staph. A.
(anti-phag) |
|
What produces Lipoteichoic acid (function)
|
all Gram +
(attachment to host cells) |
|
Why are Gram + organisms (as opposed to gram neg) predominately associated with endocarditis?
|
lipoteichoic acid allows adhesion to the valve.
|
|
function of N. gonorrhoeae pili
|
-antiphagocytic
- antigen variation |
|
What organism produces Hyaluronidase? (function)
|
GAS
(hydrolysis of Ground substance) |
|
What organisms produce IgA proteases (function)
|
Neisseria
Haemophilus Strpt. Pneumo |
|
Organisms that express Collagenase
|
Clostridium Perfringens
Prevotella |
|
organisms that express kinases (function)
|
Strept. and Staph.
(hydrolyis of fibrin) |
|
what organism expresses Lecithinase (alpha toxin)
|
C. perfringens
|
|
What organisms express Heparinase
|
B. fragilis
Prvotella |
|
name the obligate intracellular pathogens
|
All Rickettsiae
All Chlamydiaceae All viruses mycobacterium leprae some protozoa |
|
name the obligate intracellular protozoa
|
Plasmodium
Toxoplasma gondii Babesia Leishmania T. Cruzi |
|
are there obligate intracellular fungi?
|
no
|
|
name the organisms that cannot be cultured but are extracellular
|
T. Pallidum
PCP |
|
name the facultative intracellular fungi
|
Histoplasma
|
|
name the facultative intracellular bacteria part 1
|
MTB
non-TB mycobacteria Listeria monocytogenes Franscisella tularensis Brucella |
|
name the facultative intracellular bacteria part 2
|
S. typhi
Legionella pneumophilia Y. Pestis Nocardia Borrelia burgdorferi |
|
name the KEY bacteria that have exclusively human reservoirs
|
MTB
M. Leprae Shigella S. Typhi Rickettsia prowazekii |
|
other bacteria with exclusively human reservoirs
|
GAS
Neisseria C. Dip. pneumococcus T. pallidum Chlaymydophila trachomatis |
|
organism associated with cat bites
|
Pasteurella multocida
|
|
Zoonotics
name the vibrio species associated with fish |
vibrio parahaemolyticus
|
|
Zoonotics
name the vibrio species associated with oysters |
vibrio vulnificus
|
|
name the zoonotic pathogen associated with birds and atypical pneumonia
|
chlamydophila psittaci
|
|
name the zoonotic organisms part 1
|
B. anthracis
Salmonella Leptospira Borrelia |
|
name the zoonotic organisms part 2
|
Listeria
Brucells Francisella tularenis Yersina |
|
name the zoonotics part 3
|
Campylobacter
Rickttsia Coxiella |
|
name the vector for Chagas disease
|
kissing bugs
|
|
name vector for malaria
|
Anopheles mosquitos
|
|
name the vector for Dengue
|
Aedes mosquito
|
|
Name the mosquito borne encephalitides
|
WEE
EEE VEE SL |
|
name the yellow fever vector
|
Aedes mosquito
|
|
other mosquio born pathogens
|
filariasis (also transmitted by midges)
West Nile virus |
|
name the most important disease transmitted via sanflies
|
Leishmanias
|
|
other diseases transmitted by sandflies
|
viral sandfly fever (well, that's totally unexpected)
bartonellosis |
|
diseases transmitted by blackflies
|
onchocerciasis
|
|
vector for African trypanosomiasis
|
tsetse flies
|
|
dieseases transmitted by deerflies/horse flies
|
loaloasis
tularemia |
|
diseases transmitted via flea
|
plague
endemic typhus |
|
rocky mountain spotted fever is transmitted via?
|
dermacentor tick
|
|
colorado tick fever is transmitted via
|
dermacentor tick
|
|
name the Lyme disease vector
|
Ixodes tick
|
|
Name the Ehrlichia vector
(Key to diagnosis?) |
Ixodes tick
(morula) |
|
name the Babesiosis vector
|
Ixodes tick
|
|
name the diseases transmitted by Ixodes
|
Lyme Disease
Ehrlichia Babesiosis |
|
name the other important diseases transmitted via tick
|
Tularemia
Recurrent fever (tick borne relapsing fever) |
|
name the mite borne illnesses
|
scrub typhus
Rickettsialpox |
|
name the TORCH pathogens
|
toxoplasmosis
Other (syphillis) Rubella CMV HSV and HIV |
|
name the non-contagious infections
|
NTB Mycobacteria
non-sporulating anaerobes LEGIONELLA all non-dermatophilic fungi |
|
parasitic infections that cross the placenta
|
Toxoplasma
|
|
Bacterial infections that cross the placenta
|
T. pallidium
Listeria |
|
viral infections that cross the placenta
|
HIV
Polio Coxsackie B HSV2 CMV Rubella |
|
name the worms transmitted by ova (common name)
|
Enterobius vermicularis (pinworm)
Ascaris loumbricoides (roundworm) |
|
other parasitic infections transmitted by ova
|
Toxocara canis (visceral larva migrans)
Echinooccus Taenia solium |
|
name the bacteria transmitted sexually
|
Chlamydophila
Neisseria Treponema Trichomonas |
|
name the viruses transmitted sexually
|
HIV
HPV HSV2 CMV |
|
name the diseases transmitted by non-sexual contact
|
Impetigo (both Staph and Strept)
Staph. ifns HSV1 EBV HBV |
|
granuloma forming ifns
(idiotic mnemonic) |
(Fran Likes My Pal Bruce And His Blasted Cockerspaniel (in) Blessed SLC)
(F)rancisella (L)isteria (M)ycobacteria T. (P)allidium (B)rucella (A)ctinomyces (H)istoplasma (B)lastomyces (C)occidiodes (B)erylliosis (S)arcoid (L)ymphogranuloma venrum (C)at scratch fever |
|
infections that cause intracerebral calcifications
|
Toxoplasma
CMV Cysticercosis Cryptococcus MTB meningitis |