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5 Cards in this Set
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- Back
Spirochete
Treponema pallidum Syphillis |
Transmission/Vector: Direct sexual/mucous membrane contact
Reservior: Human Stages: Primary: painless skin lesion - chancre Secondary: skin lesion(s) Latent: positive antibody - no clinical signs Tertiary: tissue destruction, granulomatous lesion - gumma Diagnosis: direct darkfield microscopy, direct flourescent antibody. Nontreponemal: VDRL, RPR Treponemal: TPI, MHA-TP |
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Spirochete
Borrelia vincenti acute necrotizing ulcerative gengivitis Vincent's angina - trench mouth |
Diagnosis: Gram stain from lesion - spirochetes and G(-) fusiform bacteria
Stress and neglect of oral hygiene may contribute. |
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Spirochete
Borrelia recurrentis EPIDEMIC relapsing fever |
Transmission/Vector: human body louse
Reservior: human Stages: cycles of symptomatic/asymptomatic periods due to antigenic variation in the outer membrane, due to genetic rearrangement. NON-ZOONOTIC Diagnosis: organism in blood easily seen during FEBRILE periods |
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Spirochetes
Borrelia recurrentis ENDEMIC relapsing fever |
Transmission/Vector: tick
Reservior: rodents, soft-bodied ticks Stages: cycles of symptomatic/asymptomatic periods due to antigenic variation in the outer membrane, due to genetic rearrangement. Diagnosis: organism in blood easily seen during FEBRILE periods ZOONOTIC |
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Spirochete
Borrelia burgdorferi Lyme disease |
Transmission/Vector: hard tick - Ixodes
Reservior: rodents, deer, ticks Stages: First: red expanding skin lesion - erythema migrans. Flu-like symptoms. Second: Neurological, cardiac, MS Third: Severe neuro, card, arthritis Serology should be used only to support clinical diagnosis. Most frequently reported vector-borne disease in US. Vaccine now avail. |