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57 Cards in this Set

  • Front
  • Back
Bacterial Diseases- Urinary System
Proximity of anus to urinary opening
Intestinal bacteria predominate in urinary tract infections
Urinary Infections
Urethritis- inflammation of urethra
Cystitis- inflammation of urinary bladder
Ureteritis- inflammation of ureters
Cystitis
DESCRIPTION/ALIAS: Inflammation of Urinary Bladder
DISEASE: Bacterial
PATHOGEN: E. coli or Staphy. saprophyticus (coagulase-neg)
ORGAN SYSTEM: Urinary
Transmission:
AFFECTS: Common urinary bladder infection in females
SYMPTOMS: dysuria (difficult, urgent urination) and pyuria (leucocytes in the urine)
TREATMENT: Trimethoprim-sulfamethoxazole, quinolone antibiotics or ampicillin
COMMENTS:
Pyelonephritis
DESCRIPTION/ALIAS: Inflammation of the one or both kidneys
DISEASE: Bacterial
Pathogen: E. coli (75%)
ORGAN SYSTEM: Urinary
TRANSMISSION:
AFFECTS:
SYMPTOMS: fever or flank "back" pain
TREATMENT: intravenous, extended-term, broad-spectrum antibiotic- 2nd or 3rd-generation cephalosporin
COMMENTS: Scar tissue can be formed, impairing kidney function
*commonly a complication of infection elsewhere in body
*in females, typically- urinary tract infection
Leptospirosis
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN: Leptospira interrogans (spirochetes)
ORGAN SYSTEM: Urinary
TRANSMISSION: disease of domestic dogs and rats- urine; transmitted in urine-contaminated water or soil; pass through minor abrasions in mucous membrane or skin
AFFECTS: localization in kidneys may cause jaundice and poss. kidney failure
SYMPTOMS: fever, chills, headache, muscle aches
TREATMENT:
DIAGNOSIS: isolation in blood or CSF
COMMENTS: can cause severe kidney or liver disease
Gonorrhea
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN: Neisseria gonorrhoeae (Gram-neg diplococcus)- attaches to urethra wall, and mucsoal cells in oral-pharyngeal area, cervix, eyes and rectum
ORGAN SYSTEM: Reproductive
TRANSMISSION: direct contact (hand, birth canal, sexual contact areas)
AFFECTS: oral-pharyngeal area, eyes, rectum, opening of cervix, external genitals or prepubertal females
SYMPTOMS: Males- painful urination and discharge of pus from urethra; female- pain can happen, if infection spreads to uterus and uterine tubes; Males experience more symptoms, females can be unaware of infection
TREATMENT: tetracyclines (due to common dual chlamydia infections)
DIAGNOSIS: observation- Gram-neg cocci, serological diagnostic test
COMMENTS: most common reportable STD in US- '95
*complications- joints (arthritis- gonococcus in fluids), heart (endocarditis), meninges (meningitis), eyes, pharynx (pharyngeal- resembles sore throat), anus (anal- painful w/pus), ophthalmia neonatorum- infection in eyes of infants
Nongonococcal Urethritis (NGU)
DESCRIPTION/ALIAS: Inflammation of urethra, not caused by N. gonorrhoeae/nonspecific urethritis
DISEASE: Bacterial
PATHOGEN: Chlamydias (obligate intracellular parasites), typically C. trachomatis; also maybe Ureaplasma urealyticum or Mycoplasma hominis
ORGAN SYSTEM: Reproductive
TRANSMISSION:
AFFECTS: urethra, in women, common cause of pelvic inflammatory disease
SYMPTOMS: mild in males (inflammation of epididymis), asymptomatic in females (inflammation of uterine tubes may cause sterility)
TREATMENT: Tetracyclines
DIAGNOSIS: detect chlamydial DNA in urine specimens
COMMENTS: very common STD (not reportable), complications can be serious
Pelvic Inflammatory Disease (PID)
DESCRIPTION/ALIAS: collective term- any extensive bacterial infection of female pelvic organs;
DISEASE: Bacterial
PATHOGEN: N. gonorrhoeae w/ co-infection of chlamydial bacteria
ORGAN SYSTEM: Reproductive
TRANSMISSION:
AFFECTS:
SYMPTOMS:
TREATMENT:
DIAGNOSIS:
COMMENTS: infection in uterine tubes (salpingitis)- serious PID, scarring can block ovum from uterus, causing sterility or ectopic (or tubal) pregnancy
Syphilis
DESCRIPTION/ALIAS:
DISEASE: bacterial
PATHOGEN: Treponema pallidum (Gram-neg spirochetes)
ORGAN SYSTEM: Reproductive
TRANSMISSION: sexual contact, nonsexual transmission- kissing, dental work (secondary)
AFFECTS:
SYMPTOMS: primary- chancre (sore), secondary- rashes
TREATMENT:
DIAGNOSIS: in primary stage- pos in serological tests, pos for secondary stage too
STAGES: Primary- Chancre- sore at site of infection, fluid-filled (highly infectious), bacteria enters blood and lymph system;
Secondary- weeks later, rash on skin and mucous membranes, lesions- very infectious
Latent period- weeks later, most don' achieve this stage
Tertiary- after about 10 years, gummas- lesions, extensive tissue damage
COMMENTS: can be transmitted from mother to fetus years after (congenital syphilis)
Lymphogranuloma Venereum
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN: Chlamydia trachomatis
ORGAN SYSTEM: Reproductive
TRANSMISSION:
AFFECTS: found in tropical world, in southeastern US
SYMPTOMS: regional lymph nodes enlarge and become tender
TREATMENT:
DIAGNOSIS:
COMMENTS: scarring of lymph drainage ducts occasionally leads to massive enlargement of male genitalia and rectal narrowing in females
Chancroid
DESCRIPTION/ALIAS: soft chancre
DISEASE: Bacterial
PATHOGEN: Hemophilus ducreyi
ORGAN SYSTEM: Reproductive
TRANSMISSION:
AFFECTS: tropical disease
SYMPTOMS: painful ulcer on genitalia and spreads to lymph nodes
TREATMENT:
DIAGNOSIS:
COMMENTS: US cases common w/drug users
Gardnerella Vaginosis
DESCRIPTION/ALIAS: Vaginitis (infection of the vagina)
DISEASE: Bacterial
PATHOGEN: Candida albicans (fungus), Trichomonas vaginalis (protozoa), Gardnerella vaginalis (bacteria)
ORGAN SYSTEM: Reproductive
TRANSMISSION:
AFFECTS: Vagina
SYMPTOMS:
TREATMENT: Metronidazole
DIAGNOSIS: fishy odor, vaginal pH above, "clue" cells- sloughed off vaginal epithelial cells w/Gram-neg rods
COMMENTS: C. albicans- opportunist, T. vaginalis and G. vaginalis- sexually transmitted; interacts w/ anaerobic vaginal bacteria
Genital Herpes
DESCRIPTION/ALIAS: human herpesvirus 1 and 2
DISEASE: Viral
PATHOGEN: Herpes simplex virus type 1 and 2
ORGAN SYSTEM: Reproductive
TRANSMISSION: sexually transmitted
AFFECTS: genitals
SYMPTOMS: lesions- burning sensation and vesicles; infectious
TREATMENT: acyclovir (oral and topical)
DIAGNOSIS:
COMMENTS: danger of neonatal transmission (neonatal herpes)- fatal and serious neurological damage poss.; may be latent in nerve cells for years and reappear in intervals (i.e. cold sores)
Genital Warts
DESCRIPTION/ALIAS:
DISEASE: Viral
PATHOGEN: papillomaviruses
ORGAN SYSTEM: Reproductive
TRANSMISSION: sexual transmission
AFFECTS: genitals
SYMPTOMS: warts
TREATMENT:
DIAGNOSIS:
COMMENTS: papillomavirus can cause cervical cancer
AIDS
DESCRIPTION/ALIAS:
DISEASE: Viral
PATHOGEN: Human Immunodeficiency Virus (HIV)
ORGAN SYSTEM: Reproductive
TRANSMISSION: Sexual transmission, and mother-fetus
AFFECTS: immune system
SYMPTOMS:
TREATMENT:
DIAGNOSIS:
COMMENTS:
Candidiasis
DESCRIPTION/ALIAS:
DISEASE: Fungal
PATHOGEN: Candida albicans (fungus- grows in mucous membranes)
ORGAN SYSTEM: Reproductive
TRANSMISSION:
AFFECTS: mucous membranes of vagina
SYMPTOMS: irritation; sever itching; thick, yellow cheesy discharge, yeasty odor
TREATMENT: clotrimazole and miconzaole (topical); immunosuppressive drugs or broad-spectrum
DIAGNOSIS: microscopic identification of fungus
COMMENTS: Infection of mucous membranes of vagina- vulvovaginal candidiasis
Trichomoniasis
DESCRIPTION/ALIAS:
DISEASE: protozoan
PATHOGEN: Trichomonas vaginalis (protozoa)
ORGAN SYSTEM:
TRANSMISSION:
AFFECTS:
SYMPTOMS: males rarely have symptoms; females- bad odor, irritation and itching
TREATMENT: Metronidazole
DIAGNOSIS: microscopic examination of discharge
COMMENTS: T. vaginalis- normal inhabitant of vagina and male urethra; happens when acidity of vagina is disrupted allowing outgrowth
Skin Lesions
Vesicles- small, fluid-filled lesions

Bullae- skin vesicles larger than ~1cm in diameter

Macules- flat, reddened lesions

Papules- raised lesions

Pustules- contain pus
Staphylococcal Skin Infections
-Staphylococci-
spherical, Gram-pos, irregular grape-like clusters
all pathogenic forms make coagulase- conagulates fibrin in blood

-Staphy aureus-
Most pathogenic
Test- coagulase test
Makes entertoxins (affects GI tract), leukocidins (destrooy phagocytic leukocytes) and exfoliative toxin (causes scalded skin syndrome- out layers of skin peel away due to staphy toxins)
Found in nasal passages
Common hospital problem- causes infections in surgical wounds and artificial breaches of skin barrier

-Staphy epidermidis-
predominant species of coagulase-neg staphylococci
Pimples
Infections of hair follicles
Sty- eyelash follicle infection
Furuncles (boils)- abscess arising from hair follicle infection
Carbuncle- region of pus by inflamed tissue, more extensive invasion of tissue
Impetigo
Impetigo
superficial skin infection, pustules- become crusted and rupture
bacteria enters in minor lesions
common in grade school age children

Impetigo of newborn
problem in nurseries
prevention- hexachlorophene-containing skin lotion
Streptococcal Skin Infection
Streptococci-
Gram-pos spherical bacteria, grow in chains
Aerotolerant anaerobes (don't use oxygen)
Catalase-neg
Make toxins and enzymes (hemolysins)
Makes erythrogenic toxin (scarlet fever rash), deoxyribonucleases (breakdown DNA), NADase (breakdown NAD), streptokinases (dissolves blood clots), hyaluronidase (dissolve hyaluronic acid- cementing substance of CT) and leukocidins (kill WBCs)

Streptococcus pygenes-
Group A Beta-hemolytic steptococci
M protein on fibrils, adds to pathogenicity, aids in adherence
Common cause of erysipelas- disease affecting the dermis skin erupts into reddish patches, after Strep infection elsewhere
Pseudomonads
Pseudomonads-
Cause opportunistic skin infections
Common in soil, water, and plants
Resistance to antibiotics, causing problems in hospitals
Causes:
Otitis Externa
Pseudomonas dermititis

Pseudomonas aeruginosa-
Makes exotoxins and endotoxins
May cause resp. infections in compromised hosts, or in burn patients (causes blue-green pus from pyocyanin pigments)
Treatment: Silver sulfadiazine
Otitis Externa
Swimmer's ear
Pseudomonad infection of outer ear
Pseudomonas dermititis
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN: Pseudomonads
ORGAN SYSTEM: Integumentary
TRANSMISSION: warm, wet places
AFFECTS: Skin
SYMPTOMS:
TREATMENT: Gentamicin and Carbenicillin, combined
DIAGNOSIS:
COMMENTS: organism is resistant to chlorines
Acne
DESCRIPTION/ALIAS: most common skin disease
DISEASE: Bacterial
PATHOGEN: staphylococci and Propionibacterium acne (diphtheroids)
ORGAN SYSTEM: Integumentary
TRANSMISSION:
AFFECTS:
SYMPTOMS: Skin
TREATMENT: Benzoyl peroxide, tetracyclines; Tretinoin (Retin-A) prevents acne lesions; isotretinoin inhibits sebum formation- treats cystic acne (may cause birth defects-teratogenic)
DIAGNOSIS:
COMMENTS: sebum accumulates, making whiteheads and blackheads; accumulation ruptures the hair-follicle; P. acne breaksdown sebum, causing inflammation and scarring
Warts
DESCRIPTION/ALIAS:
DISEASE: Viral
PATHOGEN: Papillomavirus
ORGAN SYSTEM: Integumentary
TRANSMISSION: direct contact
AFFECTS: Skin
SYMPTOMS: uncontrolled nonmalignant growth of skin cells (warts)
TREATMENT: burning them w/acids, liquid nitrogen (cryotherapy), electrodesiccation
DIAGNOSIS:
INCUBATION: several weeks
COMMENTS: 50 types of papillomavirus; Genital warts- TREATMENT- injected interferon and lasers
Smallpox
DESCRIPTION/ALIAS: Variola
DISEASE: Viral
PATHOGEN: poxvirus; smallpox (variola) virus
ORGAN SYSTEM: Integumentary
TRANSMISSION: respiratory route, move through bloodstream (viremia) to infect skin
AFFECTS:
SYMPTOMS:
TREATMENT: vaccination eliminated smallpox
DIAGNOSIS:
COMMENTS: Variola major- mortality rate- 20% or more; Variola minor- mortality rate- less than 1%; recovery from one give immunity to both
Chickenpox and Shingles
DESCRIPTION/ALIAS: Varicella and Herpes Zoster
DISEASE: Viral
PATHOGEN: herpesvirus varicella-zoster (human herpesvirus 3)
ORGAN SYSTEM:
TRANSMISSION: Varicella (Respiratory route)
AFFECTS: causes chickenpox and may remain latent in nerve cells and later be reactivated to cause Shingles (herpes zoster)
SYMPTOMS: pox, vesicles on waist, upper chest, and face, affecting nerve branches of cutaneous sensory nerves
TREATMENT:
DIAGNOSIS:
INCUBATION: ~2 weeks (in school), vesicular in 3-4 days
COMMENTS: Varicella (mild disease- 2nd most common reportable)
Reye's Syndrome
DESCRIPTION/ALIAS:
DISEASE: Viral
PATHOGEN: Human herpesvirus 3
ORGAN SYSTEM: Integumentary
TRANSMISSION: complication of other viral infections
AFFECTS: Skin
SYMPTOMS: brain damage or death, due to brain swelling, preventing blood circulation
TREATMENT:
DIAGNOSIS:
COMMENTS: occasional, severe complication of chickenpox, influenza, and other viral diseases; aspirin be increase chances of Reye's Syndrome
Herpes Simplex
DESCRIPTION/ALIAS:
DISEASE:
PATHOGEN: herpes simplex type 1 virus and type 2 (human herpesvirus 1 & 2
ORGAN SYSTEM: Integumentary
TRANSMISSION: Skin contact
AFFECTS: Skin, can be contracted in infancy and affects oral mucous membranes
SYMPTOMS: forms cold cores or fever blisters (w/stress)
TREATMENT:
DIAGNOSIS:
COMMENTS: Able to be latent for long periods, after initial infection; may cause herpes encephalitis
Measles
DESCRIPTION/ALIAS: Rubeola
DISEASE: Viral
PATHOGEN: measles virus
ORGAN SYSTEM:
TRANSMISSION: Respiratory route
AFFECTS: brain, oral mucosa
SYMPTOMS:
TREATMENT: MMR vaccine
DIAGNOSIS: Koplik spots on oral mucosa
COMMENTS: extremely dangerous; complication: encephalitis- poss causing brain damage
Rubella
DESCRIPTION/ALIAS: German measles
DISEASE: Viral
PATHOGEN: virus
ORGAN SYSTEM: Skin
TRANSMISSION: respiratory route
AFFECTS:
SYMPTOMS: light fever, macular rash or small red spots
TREATMENT:
DIAGNOSIS: hemagglutination inhibition or ELISA
COMMENTS: milder than rubeola, infection is 3rd trimester can cause congenital rubella syndrome in infants- causing deafness, eye cataracts, hearing defects and mental retardation
Fifth Disease
DESCRIPTION/ALIAS: Erythema Infectiosum
DISEASE: Viral
PATHOGEN: human parvovirus B19
ORGAN SYSTEM:
TRANSMISSION:
AFFECTS:
SYMPTOMS: mild, influenza-like, causes something like "slapped-cheek" facial rash
TREATMENT:
DIAGNOSIS:
COMMENTS:
Cutaneous Mycoses
DESCRIPTION/ALIAS:
DISEASE: Fungal
PATHOGEN: Microsporum, Trichophyton and Epidermophyton
ORGAN SYSTEM: Integumentary
TRANSMISSION: direct contact, or contact w/ fomites, dog, and cats
AFFECTS: hair, nails, and outer layers of epidermis (dermatophytes); affinity of keratin
SYMPTOMS:
TREATMENT: Topical- miconazole clotrimazole; oral- griseofulvin
DIAGNOSIS:
COMMENTS: ringworm- tinea (dermatomycoses)
Tinea capitis- ringworm of scalp
Tinea cruris- ringworm of groin (jockitch)
Tinea pedia- ringworm of feet (athlete's foot)
Mycosis
Fungal infection of the body

Great ability to resist high osmotic pressure, and low moisture- skin susceptible
Subcutaneous Mycoses
DESCRIPTION/ALIAS:
DISEASE: Fungal
PATHOGEN: Sporothrix schenckii (fungi)
ORGAN SYSTEM: Integumentary
TRANSMISSION: in wound
AFFECTS: nodules formed by growing fungus, and spread along lymphatic vessels
SYMPTOMS:
TREATMENT:
DIAGNOSIS:
COMMENTS: most common- Sporotrichosis
Candidiasis
DESCRIPTION/ALIAS:
DISEASE: Fungal
PATHOGEN: Candida albicans (yeast-like fungi)
ORGAN SYSTEM: Integumentary
TRANSMISSION: outgrowth of fungus
AFFECTS: infections in the mucous membranes of genitourinary tract (vaginitis) and oral mucosa (thrush)
SYMPTOMS:
TREATMENT: clotrimazole or miconazole
DIAGNOSIS:
COMMENTS: appear when bacterial populations are suppressed by antibiotics that don't affect fungi
Scabies
DESCRIPTION/ALIAS: tiny mite
DISEASE: Parasitic
PATHOGEN: Sarcoptes scabiei
ORGAN SYSTEM: Integumentary
TRANSMISSION: burrows under the skin to lay eggs
AFFECTS: Skin
SYMPTOMS: inflammation, itches intensely
TREATMENT: Topical- permethrin insecticide or gamma benzene hexachloride
DIAGNOSIS:
COMMENTS:
Conjunctivitis
DESCRIPTION/ALIAS: inflammation of conjunctiva- mucous membrane that lines eyelid and covers outer surface of the eyeball
DISEASE: Bacterial
PATHOGEN:
ORGAN SYSTEM: Visual
TRANSMISSION: contact during birth or unchlorinated water;
AFFECTS:
SYMPTOMS:
TREATMENT: tetracycline (inclusion); 1% silver nitrate or antibiotics (neonatal
DIAGNOSIS:
COMMENTS:
Neonatal gonorrheal ophthalmia- dangerous eye inflammation transmitted to newborn during delivery
Inclusion conjunctivitis- involves only conjunctiva
Trachoma
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN: Chlamydia trachomatis
ORGAN SYSTEM: Visual
TRANSMISSION: contact w/fomites
AFFECTS: infection of the epithelial cell of the eye
SYMPTOMS:
TREATMENT: tetracycline
DIAGNOSIS:
COMMENTS: Single great cause of blindness, scar tissue forms on cornea
Herpetic Keratitis
DESCRIPTION/ALIAS: similar to cold sores
DISEASE: Bacterial
PATHOGEN: herpes simplex type 1 virus
ORGAN SYSTEM: Visual
TRANSMISSION:
AFFECTS:
SYMPTOMS: corneal ulcers occur and may cause blindness
TREATMENT: trifluridine
DIAGNOSIS:
COMMENTS: Keratitis- caused by Acanthamoeba (amoeba)- in contact wearers; severe and may require corneal transplant
Tooth Decay
DESCRIPTION/ALIAS: Dental caries
DISEASE: bacterial
PATHOGEN: Streptococcus mutans (bacterium) (cariogenic- caries causing)
ORGAN SYSTEM: Digestive- Upper (mouth)
TRANSMISSION:
AFFECTS: converts sucrose into dextran, localizes bacteria forming holes in enamel
SYMPTOMS:
TREATMENT: Prevention- lysozyme in saliva and crevicular fluid (tooth exudate)
DIAGNOSIS:
COMMENTS: hard surface of teeth gathers large amounts of microbes, causing plaque; old plaque deposits- tartar; once enamel penetrated, bacteria decays 'dentin' and 'pulp'
Peridontal Disease
Tooth lose caused by receding of gum, exposing cementum
Includes gingivitis'
Gingivitis
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN:
ORGAN SYSTEM: Digestive- Upper (mouth)
TRANSMISSION:
AFFECTS:
SYMPTOMS: bleeding gums while brushing teeth
TREATMENT:
DIAGNOSIS:
COMMENTS: Gingivitis- infection of the gingivae (gums), most common peridontal disease
Peridontitis
DESCRIPTION/ALIAS: Chronic form of gingivitis
DISEASE: Bacterial
PATHOGEN: Porphytomonas species
ORGAN SYSTEM: Digestive- Upper (mouth)
TRANSMISSION:
AFFECTS: teeth and gums
SYMPTOMS: gums inflamed and bleed, pus surrounds, in pockets,the teeth, tooth loss after destruction of bone and tissue
TREATMENT:
DIAGNOSIS:
COMMENTS:
Acute Necrotizing Ulcerative Gingivitis
DESCRIPTION/ALIAS: Vincent's disease or trench mouth
DISEASE:
PATHOGEN: Prevotella intermedia
ORGAN SYSTEM: Digestive- Upper (mouth)
TRANSMISSION:
AFFECTS: mouth
SYMPTOMS: chewing pain, foul breath
TREATMENT:
DIAGNOSIS:
COMMENTS: serious mouth infection
Bacterial Diseases- Lower Digestive System
Intoxication- disease resulting from the ingestion of toxins in food by microbial growth
Infection- a disease resulting from microbe growth in tissues
Dysentery-
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN:
ORGAN SYSTEM: Lower Digestive Sys
TRANSMISSION:
AFFECTS:
SYMPTOMS: severe diarrhea w/ blood and mucus
TREATMENT:
DIAGNOSIS:
COMMENTS:
Gastroenteritis-
DESCRIPTION/ALIAS: inflammation of stomach and intestinal mucosa
DISEASE: Bacterial
PATHOGEN:
ORGAN SYSTEM: Lower Digestive Sys
TRANSMISSION:
AFFECTS:
SYMPTOMS: abdominal cramps, nausea, and vomiting
TREATMENT: oral hydration therapy to replace fluids
DIAGNOSIS:
COMMENTS:
Staphylococcal Food Poisoning
DESCRIPTION/ALIAS: Staphylococcal Entertoxicosis
DISEASE: Bacterial
PATHOGEN: Staphylococcus aureus
ORGAN SYSTEM: Digestive System
TRANSMISSION: in food, contamination on fingers or skin lesions
AFFECTS: Lower Digestive Sys
SYMPTOMS: nausea, vomiting and diarrhea
TREATMENT:
DIAGNOSIS: phage typing of bacteria
INCUBATION: 1-6 hrs after ingestion
COMMENTS: Makes an enterotoxin (Serological type A)- heat-resistant, drying resistant, radiation, osmotic pressures; coagulase-pos staphy make coagulase- enzyme- coagulates blood plasma;
High Incidence- custard, cream pies, and ham (due to sugar or curing agents), suppresses nonstaphylococcal competition
Pathogenic staphy ferment mannitol, make hemolysis, coagulase-pos, no spoilage of foods
Shigellosis
DESCRIPTION/ALIAS: Bacillary Desentery
DISEASE: Bacterial
PATHOGEN: Shigella- S. sonnei (most common in US), S. dysenteriae, S. flexneri, S. boydii (shiga toxin)
ORGAN SYSTEM: Digestive System- Lower
TRANSMISSION:
AFFECTS:
SYMPTOMS:
TREATMENT:
DIAGNOSIS:
COMMENTS: S. sonnei- mild disease, S. dysenteriae- more sever, not common in US
Salmonellosis
DESCRIPTION/ALIAS: Salmonella Gasteroenteritis
DISEASE: Bacterial
PATHOGEN: numerous serovar of Salmonella
ORGAN SYSTEM: Digestive
TRANSMISSION: ingestion of organism and growth of cell in intestinal tract
AFFECTS: common inhabitant of Intestinal tract of animals, poultry and eggs- frequent sources
SYMPTOMS: moderate fever, nausea, diarrhea, low mortality rate
TREATMENT:
DIAGNOSIS: Kauffmann-White serological scheme- identify serovars and assign numbers and letters to different antigens:
O- somatic or body, Vi- capsular, H- flagellar
INCUBATION: 12-36 hrs
COMMENTS: all serovars are a little pathogenic
Typhoid Fever
DESCRIPTION/ALIAS: very virulent serovar of salmonella
DISEASE: Bacterial
PATHOGEN: Salmonella typhi
ORGAN SYSTEM: Digestive System- Lower
TRANSMISSION: Carriers transmit/spread disease in feces after recovery
AFFECTS:
SYMPTOMS: fever, malaise; diarrhea in late stages (2nd or 3rd week), also poss. perforation of intestinal wall and dissemination (severe cases)
TREATMENT: 3rd generation cephalosporins
DIAGNOSIS:
INCUBATION: ~2 weeks
COMMENTS:
Cholera
DESCRIPTION/ALIAS:
DISEASE: Bacterial
PATHOGEN: Vibrio cholerae; 2 types: group O:1 causes epidemic form of disease, non-O:1 group, similar but not epidemic form
ORGAN SYSTEM: Digestive System- Lower
TRANSMISSION: fecal-oral route
AFFECTS:
SYMPTOMS: rapids loss of bodily fluids and electrolytes, violent vomiting; bloody stools and fever
TREATMENT: replacement of lost fluids and electrolytes, antibiotics not very effective; untreated-death rate as high as 50%, 1% when treated
DIAGNOSIS:
COMMENTS: makes enterotoxin in intestines; indigenous in Pacific and Gulf coastal waters (non O:1), more invasive, cause bloody stools and fever
Vibrio Gastroenteritis
DESCRIPTION/ALIAS: gastroenteritis similar to cholera but milder
DISEASE: Bacterial
PATHOGEN: Vibrio parahaemolyticus, V. vulnificans
ORGAN SYSTEM: Digestive System
TRANSMISSION: V. vulnificans- ingested w/ raw oysters
AFFECTS: GI system
SYMPTOMS:
TREATMENT:
DIAGNOSIS:
COMMENTS: in coastal waters, outbreaks associated w/ seafood; most common gastroenteritis in Japan; requires sodium; very dangerous in immunocompromised or suffer from liver disease
Traveler's Diarrhea
DESCRIPTION/ALIAS: Echerichia coli Gastroeneritis
DISEASE: Bacterial
PATHOGEN: Echerichia coli, serovar O157:H7-best known
ORGAN SYSTEM: Digestive System- Lower
TRANSMISSION:
AFFECTS: inhabitant of GI tract, typically harmless
SYMPTOMS: causes traveler's diarrhea,cause outbreaks of epidemic diarrhea in nurseries
TREATMENT:
DIAGNOSIS:
COMMENTS: pathogenic strains have adhesins that help in attachment to intestinal mucosa; make enterotoxin (enterotoxigenic E. coli), invades lining of large intestine (enteroinvasive E. coli) or no well-understood mechanisms (enteropathogenic E. coli); makes a toxin- causes hemorrhagic colitis and hemolytic uremic syndrome