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33 Cards in this Set
- Front
- Back
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Sterilization
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Removal/ destruction- all forms- microbial growth
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Prions
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High resistance
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Sterilization's most common form
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Heating
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Disinfection
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Destructions of pathogenic agents (non living)
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Antisepsis
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Destruction of pathogenic agents (living)
ex: skin |
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Sanitizer
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Lower microbial counts
minimize disease transmission high temp wash then disinfect |
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Sepsis/ Septic
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Presence- toxin or pathogenic agent in blood or tissue
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Aseptic
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Minimize contamination
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Degermination
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Mechanical removal
ex: alcohol swab area before needle injection |
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---cide
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kill
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---stat
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inhibit growth/ stop reproduction
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---lytic
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destruction
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---lysis
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burst open
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Enviornmental factors that affect antimicrobials
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Temp
pH Pure vs. Mixed Culture Mixed w/ organic material (buffer) |
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Antibiotics effect ________ microbes
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specific
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Factors that affect antimicrobials
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Microbe concentration
Enviornment Exposure Time Specific microbial characteristics |
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Decimal Reduction Time (DRT)
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90% microbial population killed at a certain temp
or time necessary to decrease population 10 times |
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Thermal Death Point (TDP)
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lowest temp all microbes - liquid suspension
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Thermal Death Time (TDT)
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minimal length all microbes- liquid culture= killed at specific temp
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Radiations two parts
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ionizing
non ionizing |
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Ionizing Radiation is formed into
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hydroxyl free radicals- damage DNA
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Non- Ionizing Radiation purpose is to
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kill
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Non-Ionizing Radiation UV light
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damages organic cell components
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What 3 things does pasteurization do
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eliminates pathogens
reduces spoilage lower microbial number |
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What does filtration do
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sterilize heat-sensitive materials
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Desiccation
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water absence
microbes cannot grow or reproduce, viable for years |
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Lyophilization
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freezing substance
(freeze-drying) |
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Low temps effect _______
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specific organisms (0-7 degrees C)
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preserve foods=
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high concentration of salts and sugars
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hypertonic (high)
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water leaves cell
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desiccation denies
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cell moisture for growth
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molds and yeasts require ______moisture, which is ______ osmotic pressure
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low, high
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Minimal Inhibitory Concentration
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lowest concentration of chemotherapeutic agent that kills test microbes
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