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10 Cards in this Set

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Streptococcal Pharygitis (Strep Throat)
Microbe: gram+, strep
Transmission: airborne respiratory droplets, saliva, nasal secretions
Mechanism: M protein and hyaluronic acid capsule, attach to pharyngeal or dermal epithelial cells
Consequences: Sudden fever, sore throat w/white patches, difficulty swallowing
Treatment: Pencillin or amoxicillin
Scarlet Fever
Microbe: gram+ strep
Transmission: Contact with saliva or nasal secretions, airborne respiratory droplets
Mechanism: Erythrogenic (reddening) toxin, M protein
Consequence: sore throat, fever, rough sandpaper-like rash
Treatment: Penicillin, antihistamines to relieve itching
Diptheria
Microbe: Corynebacteria,
Transmission: Respiratory tract (coughing, sneezine, etc.)
Mechanism: Bacteriophage integrates toxin encoding DNA. A-B exotoxin
Consequence: Fuzzy gray/black thick coating in nose, throat, or airways. Difficulty swallowing, breathing, double vision, slurred speech.
Treatment: Anti-toxin shot, pencillin, prevent with DPT vaccine
Pneumococcal pneumonia
Microbe: Strep pneumoniae
Transmission: direct contact or inhalation of droplets
Mechanism: Dense capsule, has ~90 serotypes
Consequence: fluid-filled alveoli (interferes with oxygen uptake)
Treatment: Fluoroquinolone, antisera, or chemotherapy. Prevented by conjugated vaccine
Mycoplasmal pneumonia
Microbe: lack cell wall, colonies have fried-egg apperance
Transmission: direct contact/inhalation of droplets
Mechanism: Lack of cell wall protects it from antibiotics targeting the cell wall
Consequence: persistent respiratory symptoms, low fever, headache, and cough
Treatment: Tetracycline (quickly eliminates symptoms but not bacteria)
Legionellosis
Microbe: gram -, aerobic
Transmission: Natural waters, a/c cooling towers
Mechanism: replicates in macrophages, biofilms
Consequences: High fever, and pneumonia, potentially fatal
Histoplasmosis
Microbe: (fungus)
Transmission: Not contagious, inhalation of spores, bird/bat droppings
Mechanism: lives/divides in macrophages
Consequence: Lung infection causing lesions
Treatment: Amphotericin B, itraconazole (antifungal)
Common Cold
Microbe: commonly rhinovirus (50%)
Transmission: Direct contact with nasal/saliva secretions
Mechanism: hard to target with vaccine
Consequence: sneezing, runny nose, congestion, laryngitis and otitis media
Treatment: cough suppresents, antihistamines.
Influenza (Flu)
Transmission: Coming in contact with someone infected, saliva secretions, etc.
Mechanism: Antigenic variation, (HA), (NA) spikes
Consequence: chills, fever, headache, muscular aches
Treatment: Relenza, Tamiflu (can slow replication of virus if taken withing 30 hours of onset). Prevent with flu vaccine
Whooping Cough
Microbe: Bordetella pertussis, gram-
Transmission: respiratory secretions
Mechanism: Capsule, tracheal
cytotoxin (damages ciliated cells), pertussis toxin (inhibits innate immune system)
Consequence: 1- Catarrhal stage (like common cold), 2- Paroxysmal stage (violent coughing due to damaged ciliary escalator, mucus can block airway, broken ribs and brain damage due to severity of coughing) 3- Convalescence stage (recovery)
Treatment: Prevent with DTaP vaccine