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40 Cards in this Set

  • Front
  • Back
What was the fear during and after the first Gulf War in the early 1990’s?
Nature of their "germ weapon" capacity (could potentially kill everyone)
What facility is in Manassas, VA? What is its function?
American Type Culture Collection-- repository for virus and bacteria (used for study)
How did Iraq obtain deadly microorganisms?
Ordered them from the ATCC in VA through mail
Who pioneered germ warfare? When and why did this begin?
U.S. in 1943
Combat other nations who had begun to use these deadly weapons
What happened in Fort Detrick?
Converted to a biological defense program in 1969 that was guarded by armed individuals
What happens if you inhale Bacillus anthracis spores?
Develop symptoms within a week ---> respiratory anthrax
How is respiratory anthrax treated? What happens if it is not treated promptly?
Antibiotics
If not treated within the first week of symptoms, the chances of survival are very low
What are other forms of anthrax? Are they more or less serious than respiratory anthrax?
Skin and Intestinal
Less serious and more common
What methods did the US military design to deliver biological weapons?
Sprayers and drones (delivered through exhaust smoke)
What is a major advantage (militarily) to biological weapons? Why did the US also see this as a disadvantage?
Advantage: delay between delivery and effect (good for indiscriminate targets)
Disadvantage: too imprecise and not needed
What US president renounced bio-weapons? When? Did other countries agree?
Nixon in 1969
Yes, over 100 countries did, including the Soviet Union
What facility was found in Kazakhstan? When was it built? Why is this significant?
Largest Biochemical weapon plant in history
Created in 1982 (showed that Soviets had violated the treaty)
The Soviet Union “weaponized” the agents for which diseases? What type of organism causes these diseases? What is different about these diseases compared to anthrax?
Ebola and Marburg, viruses that are incurable and cause hemorrhagic fever
They have a higher death rate than anthrax
Compare the effects of TNT, gas or bio-weapons in a warhead.
TNT: 10,000m^2
GAS: 1,000,000m^2
BIO WEAPONS: 5,000,000-15,000,000m^2
Describe what happened (in relation to bio-weapons) when the USSR broke up.
People with expertise were released and forced to look for work...people began to employ their talented skills for cheap
Lots of equipment became available
How has biotechnology changed bio-weapon production?
Produced in large quantities
What is the difficult step in producing a bio-weapon?
Processing the germs into an inhalable form
What is the ideal size of a particle for a bio-weapon?
2-5 Microns
What is an advantage/disadvantage to a “dry” bio-weapon?
Advantage: easy to disseminate
Disadvantage: hard to prepare the product to a disseminate (aerosolize it)
Why is the electrostatic charge of a particle important?
Needs to be removed from the bio-weapon in order for it to disseminate (aerosolized form)
In the anthrax scare in the fall of 2001-what was unique about the anthrax “powder”? What did this indicate about the source of this anthrax?
Aerosolized Anthrax
Source knew what they were doing when they disseminated the product
Why is smallpox not an ideal bio-weapon?
-Hard to perform a large scale attack
-Only contagious when the victim obviously has symptoms
-Debilitating (hard to spread if the victim isn't making contact with many people)
What organism did the followers of Sri Ragneesh of Oregon use in germ warfare? What term is used to describe this type of agent?
Salmonella, an incapacitating agent
Has the US or Soviet Union used bio-weapons?
Not that we conclusively know of
What is different about the development of bio-weapons in the Soviet Union?
Much more advanced techniques are already prepared
What types of techniques did the Soviet Union use in the development of bio-weapons?
Genetic engineering with plasmids to create harsher forms of old germs/diseases
In the “synthetic” bio-weapon developed by the Soviet scientist profiled, what happened to the test animals and why? What is significant about this in terms of germ warfare?
Doctors could not diagnose the animals
Animals often died of abnormal symptoms as there nervous system was often attacked by the "self"
Shows that synthetic bio-weapons could be massively destructive
Are terrorists likely to use “designer bugs”? Why or why not? What are “oldie-moldies”?
No because of their means/needs
Anthrax, Botulism, and Plague
What happened in the early disaster drills after 9/11?
The chaos led to overwhelming coordination and communication
What is being done now to combat the threat of germ warfare?
-Development of high tech, traveling equipment
-Large stockpiles of vaccines and antibiotics
-Extensive research for etiology
What are the usual symptoms of the disease in Contagion?
-Seize
-Heart Failure
-Foaming at the Mouth
-Chills
-Rapid Death
What is Rsub0 represent?
The number of people that an infected individual is likely to infect OR reproduction rate of the virus
How do they believe the virus may be transmitted in Contagion?
Respiratory or Fomites
What types of sequencing does the disease in Contagion share with other animals?
Pig and Bat
What is the first problem that they have with creating a vaccine?
The virus kills any cell that the scientists try to grow it in
What is the name of the virus?
MEV1
Where do they believe that Beth Emhoff contracted the disease?
Contracted it from a man she shook hands with at a restaurant in Hong Kong who had touched the infected mouth of a slaughtered pig which had eaten a banana infected by a virus that came from a bat
What drug does the blogger Allen convince his readers is the key to protecting yourself from the MEV-1 virus?
Forsythia
What vaccine does Hextall finally see work? How does she know the vaccine worked?
Vaccine #57
This monkey who had been injected with the disease and vaccine had not died
How does the CDC determine who gets vaccinated?
Decide to have a drawing based on birth date
First Date is 3/10