Microbes 2008 - Organisms

Front 1

S. aureus

1.Gram stain
2.Shape
3.Catalase
4.Coagulase
5.Encounter
6.Virulence factors

Back 1

1.Gram+
2.Cocci, in clusters
3.Catalase positive
4.Coagulase positive (diagnostic)
5.Normal flora of skin and mucosa (nose)
6.Cytotoxins that kill PMNs; TSST

Front 2

Strep pyogenes

1.Group
2.Gram stain
3.Shape
4.Catalase
5.Identifying factors
6.Virulence factors

Back 2

1.Group A Strep
2.Gram+
3.Cocci, in chains
4.Catalase negative
5.Type-specific M protein in cell wall
6.Capsule; M protein (anti-phagocytic, degrades complement C3b); pyrogenic exotoxins (superantigens); Streptolysin (lyses cells, including phagocytes)

Front 3

Neisseria menigitidis

1.Gram stain
2.Shape
3.Catalase
4.Ferments

Back 3

1.Gram-
2.Diplococci
3.Catalase positive
4.Ferments glucose and maltose
5.Intracellular, capsule

Front 4

Clostridium botulinum

1.Gram stain
2.Shape
3.Identifying factors
4.Virulence factors

Back 4

1.Gram+
2.Bacillus
3.Strict anaerobe, spore-forming
4.Botulinum toxin

Front 5

Pseudomonas aeruginosa

1.Gram stain
2.Shape
3.Oxidase
4.Identifying factors
5.Virulence factors

Back 5

1.Gram-
2.Bacillus
3.Oxidase positive
4.Mucoid exopolysaccharide capsule
5.Capsule; Biofilm formation

Front 6

MacKonkey agar

Back 6

Grows only gram-, contains lactose (fermenters are pink)

Front 7

Group A Strep toxins

Back 7

Strep pyogenes, pyrogenic exotoxins; superantigens, cause Scarlet fever

Front 8

Staph aureus toxins

Back 8

Epidermolytic A or B, serine protease that cleaves desmoglein in CT, leads to scalded skin syndrome

Front 9

C. diptheriae toxin

Back 9

Diptheria toxin; binds EGF-like growth factor receptors, blocks protein synthesis, ADP-ribosylates EF-2, kills cell (esp heart and neurons)

Front 10

Bordatella pertussis toxin

Back 10

Pertussis toxin; ADP-ribosylates G-proteins leading to high cAMP; affects immune function

Front 11

Clostridium botulinum toxin

Back 11

Botulinum toxin; cleaves synaptobrevin, blocks ACh release leading to flaccid paralysis

Front 12

Clostridium tetani toxin

Back 12

Tetanus toxin; transported to inhibitory neurons, cleaves synaptobrevin, prevents release of inhibitory neurotransmitters leading to tetanus

Front 13

Vibrio cholerae toxin

Back 13

Cholera toxin; ADP-ribosylates G-protein resulting in persistent activation of adenyl cyclase, excess sodium and water excretion

Front 14

Staph aureus toxins

Back 14

TSST; Panton-Valentine leukocidin, pore formation (especially PMNs), leads to tissue necrosis and inhibition of phagocytosis; Epidermolytic A,B

Front 15

Bacillus anthracis

1.Category
2.Gram stain
3.Diseases caused

Back 15

1.Category A
2.Gram+
3.Inhalation anthrax, intestinal, cutaneus

Front 16

Yersinia pestis

1.Category
2.Gram stain
3.Diseases caused

Back 16

1.Category A
2.Gram-
3.Pneumonic plague, bubonic plague

Front 17

Francisella tularensis

1.Category
2.Gram stain
3.Diseases caused

Back 17

1.Category A
2.Gram-
3.Tularemia (sudden fever, chills, headaches, muscle aches, joint pain, dry cough, progressive weakness, PNEUMONIA)

Front 18

Clostridium difficile

1.Shape
2.Gram stain
3.Disease

Back 18

1.Bacillus, spore-former
2.Gram+
3.Pseudomembranous colitis (diarrhea, esp. w/ exposure to antibiotics)

Front 19

Haemophilus influenzae

1.Gram stain
2.Growth medium
3.Shape
4.Adhesins

Back 19

1.Gram-
2.Chocolate agar w/ factor X,V
3.Bacillus
4.Gap(s)-autoproteolysis except in presence of SLPI, w/ SLPI leads to aggregates

Front 20

Hepatitis C

1.Description

Back 20

1.Enveloped, SS-RNA, positive sense

Front 21

Tinea

Back 21

Cutaneous

Front 22

Histoplasmosis

Back 22

Systemic

Front 23

Coccidiomycosis

Back 23

Subcutaneous

Front 24

Sporothrix

Back 24

Subcutaneous