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7 Cards in this Set
- Front
- Back
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How does mycobacteria resist cell-mediated immunity?
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By inhibiting phagolysosomal fusion
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How does herpes simplex resist cell-mediated immunity?
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By interfering with the TAP transporter which presents antigen presentation on MHCI
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How does CMV resist cell-mediated immunity?
(two ways) |
1. Inhibits proteasomal activity
2. Removes class I MHC from ER |
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How does EBV resist cell-mediated immunity?
(two ways) |
1. Inhibits proteasomal activity
2. Produces IL-10 which inhibits macrophage activation! (TH2-ish) |
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How does the pox virus resist cell-mediated immunity?
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By producing soluble cytokine receptors that blunt the cell-mediated immune response.
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What causes the symptoms of toxic shock syndrome?
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Massive and unregulated cytokine production
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What triggers the cytokine production in TSS?
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Superantigen which triggers Tcells nonspecifically.
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