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11 Cards in this Set

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What are chemokines?
Chemotactic cytokines
What do chemokines stimulate?
Directed migration and regulated movement of leukocytes from the blood into the tissues.
What type of receptors are the chemokine receptors?
GPC 7-transmembrane receptors
What types of immunity are the complement proteins involved in?
Both innate and adaptive
What are defensins?
Small cationic peptides that can lyse microbes
What produces defensins?
-phagocytes
What are the acute phase reactants released in inflammation?
CRP and Serum amyloid A
How does the innate immune system activate adaptive immunity?
IT PROVIDES THE 2ND SIGNAL! FOR ACTIVATION OF T AND B CELLS
What are the 3 things that provide the 2nd signal for adaptive activation?
-Costimulatory molecule
-Cytokines IL-12
-Complement proteins
What disease is associated with complement deficiencies?
Hereditary angioedema
What disease is associated with Phox deficiency?
CGd