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11 Cards in this Set
- Front
- Back
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What are chemokines?
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Chemotactic cytokines
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What do chemokines stimulate?
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Directed migration and regulated movement of leukocytes from the blood into the tissues.
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What type of receptors are the chemokine receptors?
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GPC 7-transmembrane receptors
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What types of immunity are the complement proteins involved in?
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Both innate and adaptive
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What are defensins?
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Small cationic peptides that can lyse microbes
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What produces defensins?
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-phagocytes
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What are the acute phase reactants released in inflammation?
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CRP and Serum amyloid A
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How does the innate immune system activate adaptive immunity?
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IT PROVIDES THE 2ND SIGNAL! FOR ACTIVATION OF T AND B CELLS
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What are the 3 things that provide the 2nd signal for adaptive activation?
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-Costimulatory molecule
-Cytokines IL-12 -Complement proteins |
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What disease is associated with complement deficiencies?
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Hereditary angioedema
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What disease is associated with Phox deficiency?
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CGd
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