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33 Cards in this Set

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what is the purpose of bioterrorism

bio warefare

chemical warefare
terrorism: scare ppl, cause death/disease. can affect masses or just a small group

warfare: INTENTIONAL use of bugs/toxins/ for disease/death of human, animal or plants

chemical: use smoke, irritants, gas etc to injure/kill

**warfare and terrorism is NOT the same. Terrorism is to make military ineffective, deny terrian. scare ppl, shut down cities adn paralyze medical system. warefare is intent to kill more
is teh purpose of chem/bio terrorism the same as warefare
nope. terrorism wants to affect military and public

military: stop advancement by making bad terrian, and make the soliders sick.ineffective. cant shoot with all that MOPS gear

public: scare ppl, stop a city (clean up etc), paraplyze medical system
what does MOPSS gear do to troups
makes it hard for them to shoot. can go potty except in suit etc. makes war conditions EVEN WORSE
what are used as agents of biowarefare
1. anthrax
2. small pox
3. plague
4. botulism
5. VEE
6. tularemia
7. q fever
8. marburg
9. influenza
10. meliodosis
11. typhus
what is an unconventional threat
just as it seems, the term came out after 9-11

*any situation that exceeds what you thought was even possible
what was the result of the 7 anthrax letters that were sent out
5 died, $$$ for clean up

1. we know you need 60 day prophylaxis bc the spore lasts a long time
2. better to use to AB than one
tell me a little about the things that make a good bioterrorism
1. mass killing: sometimes yes sometimes we just want to paralyze the system for a while

2. wont kill you but needs serious medical care

3. person to person spread: small pox, plague. NOT anthrax

4. cant detect

5. non sepcific sx: cant tell if this one will be the bad one

6. incubation: small pox~2 weeks. plague 1-2 days

7. mimics endemic disease
name the top 3 biowarefare agents
1. anthrax- vaccine available. NO P to P, prophylax 60 days

2. Small Pox- variola major

3. plague- yersinia persistis

also tularemia, hemorrhagic fevers, and botulism toxin.
tell me about anthrax
its a gram + spore former. this means we can put it in bombs and the spore will stay infective.

the bug in inhaled, but there is NO PERSON TO PERSON TRANSMISSION

incubation for like 60 days
is anthrax spread p2p
nope

But it forms spores so can last a long time if needed - aerolsolized

incubate 1-60 days
does anthrax cause pneumonia
NO

cxr shows widened mediasteinum
what bioterrorim shows a widened mediasteinum and what is its mortality
anthrax

100% mortality
ok so an anthrax bomb blew up but you held your breath, do you need to be worried about spores on your clothes
ehh, not really

secondary aerosolization is unlikely but def wach thgs w/0.5% hypochlorite
if your mom was exposed to an initial source of anthrax shoudl you be vaccinated
nope

**secondary aerosolization is NOT likely
best way to tx anthraxz
2 AB (cipro, doxy)

for like 60 days!

*prophylax for 60 days w/doxy
how is smallpox spread,
contact, inhalation

only need like 10 virions to be infective
whats the incubation for small pox

how many virions for small pox
~2 weeks or less, can be exposed and then spread

10-100 virions for infectious dose
can small pox be xpread easily
YA! its P2P and doesnt show up for like 2 weeks. so you get infected adn dont have sx but pass along to tons of ppl you contact (aerosol or contact w/lesion, low infectious dose)

**super bad bc NO effective tx, but can kinda prophylax w/small pox vaccine
the DISTRIBUTION of small pox is what
centriFUGAL- most prominant in faec and extremities
what disease has a distribution that is concentrated to face and extremities, what is this pattern called
small pox
centriFUGAL
is small pox spread person to person
ya, it spreads fast bc you dont know you are infected and pass it along, low infectious dose

centrifugal distribution of rash (fugal- furtherst- face nad extremities)
what rash is heave on trunk and spare on face
chichen pox (centripital)

contrast to small pox which is more on extremites nad face (centriFUGAL)
ok so my mom was exposed to small pox, shoudl i be worried for myself
oh ya! can spread person to person, lesins are infectious!

*secondary contamination is a big deal
whats the tx for small pox
NONE!!!! no approved antiviral

**vacine can be used kinda as prophylaxis
do anthrax or small pox pts need to be in isolation
small pox
how is plague spread? what is the incubation
Yersinia pestis through inhalation or flea bite

**incubation is like 1-2 days

P2P transmission
what causes penumonia, antrhax small pox or plague
plague

*anthrax makes wide mediasteimun
*small pox makes centrifugal rash
clinical manifestions of the plague
1. pneimona
2. dyspnea, stridor
3 GI
4. Buboes-
will plague kill you
not if you get treated

90-100% mortality w/o
tx

5% w/tx :)
is plague spread p2p
yep
is secondary comtaminatino for plague a concern
nope
whats the decontamination and isolation protocol for plague
clean EVERYTRHING woth 10% bleach

isolation for 48 hrs

AB prophylaxis and watch fever for 1 week of all sick contacts
do we wait until there is an outbreak of bioterrorism
NO, cant be complaicent. cant really prevent it in the first place so we need to ahve SUPER good measures in place for when it happen