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148 Cards in this Set
- Front
- Back
Koilocytes are associated with this type of viral infection
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Human papillomavirus
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DNA viruses that replicated entirely in the cytoplasm
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Poxviruses
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Enveloped (+) RNA virus that causes jaundice, vomiting of blood and renal
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Yellow fever
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An enterovirus associated with pericarditis
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Coxsackie B
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Causes 100's of scaly macules and papules in person with a genetic skin disorder
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HPV 5 and 8
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This (-) RNA virus may cause or worsen mental illnesses like schizophrenia
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Borna disease virus
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DNA virus commonly associated with nasopharyngeal carcinoma in Asia
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Epstein-Barr
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Enveloped (+) RNA virus that has the unusual feature that it can be spread fecal-oral
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Coronavirus
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Segmented (-) RNA virus that causes severe pulmonary disease from deer mice
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Sin nombre hantavirus
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(+) RNA virus associated with chronic liver infection and cirrhosis
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Hepatitis C
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(-) RNA virus with a linear genome of 8 segments. Infects the lungs
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Influenza
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Causes cauliflower-like skin projections on the hands and feet that regress over time
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HPV 1-4
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Coinfection with these two viral types leads to more serious hepatitis
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Hep B + D
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DNA virus that creates basophilic nuclear inclusions due to defective replication
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Adenovirus
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This (-) RNA virus family carries ribosomes and appears sandy because of it
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Arenavirus
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This viral satellite has a (-) RNA genome that encodes just one protein
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Hep D
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This virus can be reactivated to cause a vesicular rash along one dermatome
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Varicella-Zoster
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This virus grows in grey matter and causes hydrophobia, seizures, and hallucinations
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Rabies
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Neuraminidase inhibitors are used to treat infections with this (-) RNA virus
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Influenza
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A DNA virus that can cause hydrops fetalis in newborns
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Parvovirus B19
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A flavivirus in the US that infects birds and humans and can cause encephalitis
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West Nile
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This DNA virus is a common cause of deafness and mental retardation in newborns
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Cytomegalovirus
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Hepatitus virus that is a common fecal-oral virus in developing countries
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Hep E
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Koilocytes are associated with this type of viral infection
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Human papillomavirus
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This virus contains nsP4 viral enterotoxin and causes watery diarrhea
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Rotavirus
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This virus creates cytoplasmic inclusions known as Negri bodies
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Rabies
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This virus causes successive crops of a vesicular rash over the body
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Varicella-Zoster
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Non-enveloped (+) RNA virus that causes asymmetric flaccid paralysis
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Poliovirus
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DNA virus that causes a distinctive facial rash in children but arthritis in adults
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Parvovirus B19
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Enterociruses associated with vesicular lesions on the hands, feet, and mouth
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Coxsackie A and Enterovirus 71
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DNA virus that causes a simultaneous outbreak of a vesicular rash
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Variola
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Non-enveloped dsDNA virus that causes UTIs in immunocompromised patients
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BK polyomavirus
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Can cause fatal viral meningitis and is transmitted from hamsters or mice
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Lymphocytic Choriomeningitis Virus
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The cellular effects of these ciruses can be identified on Tzanck smears
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HSV and VZV
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dsRNA virus that causes tick-borne fever and can remain in the blood for months
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Coltvirus (Colorado tick fever)
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Segemented (-) RNA viruses that cause hemorrhagic fever with renal syndrome
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Hantaviruses, eg Hantaan
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These virus types cause condylomata acuminata
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HPV 6 and 11
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Fecal-oral hepatitis virus that causes significant mortality in pregnant women
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Hep E
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Virus that has either a (+) or (-) ssDNA genome
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Parvovirus B19
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The genome of this (-) RNA virus also functions as a ribozyme
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Hep D
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Virus in the Congo that causes hemorrhagic fever with bleeding
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Ebola
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DNA virus that releases large amounts of antigen into the serum as decoys
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Hep B
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Enteroviruses associated with meningitis
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Coxsackie A, B, and Echovirus
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A defective mutant of this virus causes subactue schlerosing panencephalitis
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Measles
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(+) RNA virus that can affect a respiratory regulatory center of the brain
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Poliovirus
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Enveloped (+) RNA virus that has a helical shape and causes common colds
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Coronavirus
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Causes bronchiolitis and expiratory wheezes due to necrosis of the bronchioles
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Respiratory Syncytical virus
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Diploid RNA viruses that encode RNA-dependent DNA polymerase
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Retroviruses
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This (+) RNA virus may be associated with hairy cell leukemia
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HTLV-2
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Non-enveloped DNA virus that commonly cuases pharyngitis and conjunctivitis
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Adenovirus
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Viral cause of heterophile-antibody negative mononucleosis
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Cytomegalovirus
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These virus types cause cervical cancer
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HPV 16, 18, 31, and 45
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An enterovirus that infects hepatocytes and is acquired by eating contaminated food
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Hep A
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Enveloped (+) RNA virus that caused severe pneumonia. Originated in China.
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SARS-coronavirus
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DNA virus (and its serotypes) that cause acute gastroenteritis with watery diarrhea
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Adenoviruses 40-42
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Causes roseola, a rash that is prominent on the trunk and face
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HHV-6 and -7
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This virus causes bilateral salivary gland enlargement and sometimes orchitis
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Mumps
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New strains of this virua can be created in pigs from both human, pig, and bird strains
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Influenza A
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Non-enveloped (+) RNA virus that replicated poorly at normal body temperature
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Rhinovirus
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DNA virus that encodes an RNA-dependent DNA polymerase
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Hep B
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A 2nd serotype of this virus causes severe disease due to non-neutralizing antibodies
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Dengue
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These viruses binda nd inactivate the cellular p53 and p105RB proteins
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HPVs and Polyomaviruses
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Cause acute T-cell lymphocytic leukemia
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HTLV-1
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Enveloped DNA viruses that cause latent infections in neural ganglia
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HSV and VZV
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Major RNA virus that persistently infects macrophages and is cytolytic for T cells
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HIV
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DNA virusese that carry DNA-dependent RNA polymerase within their virions
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Poxviruses
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Outer capside of this RNA virus is cleaved to the GI tract to activate virus for infection
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Rotavirus
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(+) RNA virus whose surface flycoplroteins resemble a crown
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Coronavirus
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Hepatocellular carcinoma can be attributed to chronic infection with this DNA virus
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Hep B
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Enveloped DNA viruses that cause recurrent vesicles on the mouth and genitalia
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Herpes simplex 1 and 2
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Viral cause of heterophile-antibody positive mononucleosis
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Epstein-Barr
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Causes distinctive gray oral spots followed by a maculopapular rash on the body
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Measels
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This (-) RNA virus is a viral superinfection that causes cirrhosis
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Hep D
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Respiratory virus that cuses a 3 day rash that is lighter in color than measels rash
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Rubella
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This virus produces cytoplasmic inclusions known as Guarnieri bodies
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Bariola
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This viral disease can be prevented by vaccination after virus acquisition
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Rabies
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Causes croup and a cough that sounds like a seals bark
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Parainfluenza
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Major cause of 1 day gastroenteritis, common on cruise ships
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Norovirus
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DNA virus that causes clusters of benign pink skin tumors with central indentations
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Molluscum contagiosum
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This virus denudes the lungs and allows for secondary bacterial pneumonia
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Influenza
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Lacy, reticulated, macular erythema
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Parvovirus B19
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This (+) or (-) ssDNA is associated with pericarditis
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Parvovirus B19
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Epidermodysplasia varruciformis patients which are also susceptible to squamous cell carcinoma
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HPV 5 and 8
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Oropharyngeal squamous cell carcinoma
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HPV 16
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Benign HPV head and neck tumors
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HPV 6 and 11
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Immunocompromised patients reactivate viruses causing UTIs/viremia and CNS infection.
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Polyomaviruses BK and JC
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Transforms astrocytes and kills oligodendrocytes leading to progressive multifocal leukoencephalopathy
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JC Polyomavirus
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Swimming pool conjunctivitis
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Adenovirus
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Acute viral gastroenteritis with watery diarrhea
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Adenovirus serotypes 40-42
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Acute viral respiratory disease that is high in military recruits
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Adenovirus serotypes 4 and 7
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Adenovirus serotypes that primary infect KIDS with respiratory illnesses
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Adenovirus serotypes 1, 2, 3, 5, and 6
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Only hepatitis virus that encodes DNA instead of RNA
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Hep B
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DNA virus that encodes reverse transcriptase and replicates through a circular RNA intermediate
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Hep B
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Detection of both HbsAg and HebAg in the blood indicates an ongoing active infection
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Hep B
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Viral-mediated jaundice, dark urine, pale stools
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Hep B
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Herpes simplex type that becomes latent in B cells
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EBV
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Herpes simplex viruses that becomes latent in neurons
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HSV and VZV
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Herpes simplex virus becomes latent in lymhocytes
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CMV
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Has a tegument containing proteins and enzymes that facilitate replication in non-growing cells
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Herpesviruses
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Gingivostomatitis, keratoconjunctivitis, encephalitis and herpetic whitlow
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HSV-1
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Virus becomes latent in the trigeminal nerve ganglia
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HSV-1
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Virus becomes latent in the sacral nerve ganglia
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HSV-2
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Genital herpes, neonatal infections, meningitis, and herpetic whitlow
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HSV-2
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Virus that is transmitted to humans through monkey saliva, usually causing fatal encephalopathy
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simian HSV
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Produces cells with large, purple intranuclear inclusion bodies surrounded by a halo resembling owl eyes
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Cytomegalovirus (CMV)
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Virus responsible for the failure of many kidney transplants, as well as retinitis and pneumonia
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Cytomegalovirus (CMV)
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Common viral triggers of Guillain-Barre syndrome
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Cytomegalovirus (CMV) and Epstein-Barr Virus (EBV)
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Prototype for these viral infections is acyclovir
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Herpesvirus
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Infected cells have cytoplasmic inclusion bodies called Guarnieri bodies
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Variola virus--Poxvirus
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Broad class of RNA viruses that are all helical, enveloped, and carry virus associated RNA-dependent RNA polymerase
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(-) sense ssRNA viruses
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Three (-) sense ssRNA families with segmented genomes (OBA)
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Orthomyxoviridae
Bunyaviridae Arenaviridae |
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This viral envelope glycoprotein promotes fusion of the viral and host cell membranes
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Fusion (F) protein
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Viral envelope glycoprotein inserted into cell membrane causes syncytia formation.
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Fusion (F) protein
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Viral envelope glycoproteins (2) binds sialic acid receptors
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Hemagglutinin-neuraminidase (HN)
Hemagglutinin (H) |
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Paramyxovirus with H and F glycoproteins
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Measles (Rubeola)
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Two Paramyxoviruses with F and combined HN glycoproteins
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Mumps and Parainfluenza
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Paramyxovirus with only F glycoprotein
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Respiratory syncytial virus (RSV)
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This (-) ssRNA virus starts with CCCP=cough, coryza, conjunctivits, and photophobia
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Measles (Rubeola)
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Koplik spots
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Measles (Rubeola)
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Virus presents with stridor, seal-bark cough, and subglottal swelling
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Parainfluenza virus
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Virus is localized to the respiratory tract and induced syncytia
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Respiratory Syncytial Virus (RSV)
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Most common cause of lower respiratory tract infection in young children
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Respiratory Syncytial Virus (RSV)
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Second most common cause of lower repiratory tract infection in young children
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Metapneumovirus
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Flying fox reservoirs, cause flulike symptoms, seizures, and coma.
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Nipah
Hendra |
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Bullet-shaped virus transmitted mostly by bat contact in USA
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Rabies
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Animal bite site showing pain, itching, and paresthesia, along with systemic symptoms
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Rabies
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Foot and mouth disease
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Vesicular stomatitis virus
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Filoviruses that causes extensive cell tissue necrosis
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Ebola
Marburg |
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Interferons and cytokines peak at the same time in this virus and cause the classic 'flu' symptoms
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Influenza A
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The only Bunyavirus carried by rodents
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Hantavirus
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Two (-) RNA and one ambisense strand
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Bunyaviruses
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Hemorrhagic Fever with Renal Syndrome; fever, hemorrhage, hypotension, and renal failure.
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Hantaviruses
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Segmented circular genomes; one (-) RNA and one ambisense
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Arenaviruses
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This (-) RNA virus is carried by sheep and horses and spreads through the CNS
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Bornavirus
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Only pathogen (and it's (-) RNA) to use host cell CNA-dependent RNA polymerase to make mRNA and RNA copies of the genome
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Hep D Deltavirus
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Only human virus (and it's (-) RNA) to forme an RNA ribozyme which cleaves many joined RNA genome copies into monomers)
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Hep D Deltavirus
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Proteolytic cleavage in the GI activates virus, producing an infectious subviral particle.
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Rotavirus
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Class of RNA viruses with linear, nonsegmented genomes.
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(+) ssRNA viruses
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Class of viruses that carry code for RNA dependent RNA polymerase, but not in the mature virion.
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(+) ssRNA viruses
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(+) ssRNA genome that makes (-) ssDNA with a reverse transcriptase
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Retroviruses
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Fecal-oral infection that travels from the larynx to the GI and then gains access to the brain by infecting skeletal muscle.
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Poliovirus
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This mosquito-borne (+) ssRNA virus causes a hemorrhagic fever in babies with maternal antibodies, or individuals with antibody from a previous infection.
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Dengue virus
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This virus binds to surface receptors on lymphocytes, outside of its target organ, and also inhibits apoptosis, making it very persistent.
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Hep C
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20% mortality for pregnant women in their 3rd trimester due to fulminant hepatitis.
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Hep E, Hepevirus
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Class of virus that has surface glycoprotein spikes that force the envelope to wrap tightly
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Togavirus
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This virus causes cataracts, mental retardation and deafness in fetuses when their mothers are infected.
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Rubella
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Virus has E2 proteins that are the target of neutralizing antibodies.
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Coronaviruses
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Diploid RNA viruses that encode RNA-dependent DNA polymerase (RT) and replicate through a DNA intermediate.
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Retroviruses
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