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148 Cards in this Set

  • Front
  • Back
Koilocytes are associated with this type of viral infection
Human papillomavirus
DNA viruses that replicated entirely in the cytoplasm
Poxviruses
Enveloped (+) RNA virus that causes jaundice, vomiting of blood and renal
Yellow fever
An enterovirus associated with pericarditis
Coxsackie B
Causes 100's of scaly macules and papules in person with a genetic skin disorder
HPV 5 and 8
This (-) RNA virus may cause or worsen mental illnesses like schizophrenia
Borna disease virus
DNA virus commonly associated with nasopharyngeal carcinoma in Asia
Epstein-Barr
Enveloped (+) RNA virus that has the unusual feature that it can be spread fecal-oral
Coronavirus
Segmented (-) RNA virus that causes severe pulmonary disease from deer mice
Sin nombre hantavirus
(+) RNA virus associated with chronic liver infection and cirrhosis
Hepatitis C
(-) RNA virus with a linear genome of 8 segments. Infects the lungs
Influenza
Causes cauliflower-like skin projections on the hands and feet that regress over time
HPV 1-4
Coinfection with these two viral types leads to more serious hepatitis
Hep B + D
DNA virus that creates basophilic nuclear inclusions due to defective replication
Adenovirus
This (-) RNA virus family carries ribosomes and appears sandy because of it
Arenavirus
This viral satellite has a (-) RNA genome that encodes just one protein
Hep D
This virus can be reactivated to cause a vesicular rash along one dermatome
Varicella-Zoster
This virus grows in grey matter and causes hydrophobia, seizures, and hallucinations
Rabies
Neuraminidase inhibitors are used to treat infections with this (-) RNA virus
Influenza
A DNA virus that can cause hydrops fetalis in newborns
Parvovirus B19
A flavivirus in the US that infects birds and humans and can cause encephalitis
West Nile
This DNA virus is a common cause of deafness and mental retardation in newborns
Cytomegalovirus
Hepatitus virus that is a common fecal-oral virus in developing countries
Hep E
Koilocytes are associated with this type of viral infection
Human papillomavirus
This virus contains nsP4 viral enterotoxin and causes watery diarrhea
Rotavirus
This virus creates cytoplasmic inclusions known as Negri bodies
Rabies
This virus causes successive crops of a vesicular rash over the body
Varicella-Zoster
Non-enveloped (+) RNA virus that causes asymmetric flaccid paralysis
Poliovirus
DNA virus that causes a distinctive facial rash in children but arthritis in adults
Parvovirus B19
Enterociruses associated with vesicular lesions on the hands, feet, and mouth
Coxsackie A and Enterovirus 71
DNA virus that causes a simultaneous outbreak of a vesicular rash
Variola
Non-enveloped dsDNA virus that causes UTIs in immunocompromised patients
BK polyomavirus
Can cause fatal viral meningitis and is transmitted from hamsters or mice
Lymphocytic Choriomeningitis Virus
The cellular effects of these ciruses can be identified on Tzanck smears
HSV and VZV
dsRNA virus that causes tick-borne fever and can remain in the blood for months
Coltvirus (Colorado tick fever)
Segemented (-) RNA viruses that cause hemorrhagic fever with renal syndrome
Hantaviruses, eg Hantaan
These virus types cause condylomata acuminata
HPV 6 and 11
Fecal-oral hepatitis virus that causes significant mortality in pregnant women
Hep E
Virus that has either a (+) or (-) ssDNA genome
Parvovirus B19
The genome of this (-) RNA virus also functions as a ribozyme
Hep D
Virus in the Congo that causes hemorrhagic fever with bleeding
Ebola
DNA virus that releases large amounts of antigen into the serum as decoys
Hep B
Enteroviruses associated with meningitis
Coxsackie A, B, and Echovirus
A defective mutant of this virus causes subactue schlerosing panencephalitis
Measles
(+) RNA virus that can affect a respiratory regulatory center of the brain
Poliovirus
Enveloped (+) RNA virus that has a helical shape and causes common colds
Coronavirus
Causes bronchiolitis and expiratory wheezes due to necrosis of the bronchioles
Respiratory Syncytical virus
Diploid RNA viruses that encode RNA-dependent DNA polymerase
Retroviruses
This (+) RNA virus may be associated with hairy cell leukemia
HTLV-2
Non-enveloped DNA virus that commonly cuases pharyngitis and conjunctivitis
Adenovirus
Viral cause of heterophile-antibody negative mononucleosis
Cytomegalovirus
These virus types cause cervical cancer
HPV 16, 18, 31, and 45
An enterovirus that infects hepatocytes and is acquired by eating contaminated food
Hep A
Enveloped (+) RNA virus that caused severe pneumonia. Originated in China.
SARS-coronavirus
DNA virus (and its serotypes) that cause acute gastroenteritis with watery diarrhea
Adenoviruses 40-42
Causes roseola, a rash that is prominent on the trunk and face
HHV-6 and -7
This virus causes bilateral salivary gland enlargement and sometimes orchitis
Mumps
New strains of this virua can be created in pigs from both human, pig, and bird strains
Influenza A
Non-enveloped (+) RNA virus that replicated poorly at normal body temperature
Rhinovirus
DNA virus that encodes an RNA-dependent DNA polymerase
Hep B
A 2nd serotype of this virus causes severe disease due to non-neutralizing antibodies
Dengue
These viruses binda nd inactivate the cellular p53 and p105RB proteins
HPVs and Polyomaviruses
Cause acute T-cell lymphocytic leukemia
HTLV-1
Enveloped DNA viruses that cause latent infections in neural ganglia
HSV and VZV
Major RNA virus that persistently infects macrophages and is cytolytic for T cells
HIV
DNA virusese that carry DNA-dependent RNA polymerase within their virions
Poxviruses
Outer capside of this RNA virus is cleaved to the GI tract to activate virus for infection
Rotavirus
(+) RNA virus whose surface flycoplroteins resemble a crown
Coronavirus
Hepatocellular carcinoma can be attributed to chronic infection with this DNA virus
Hep B
Enveloped DNA viruses that cause recurrent vesicles on the mouth and genitalia
Herpes simplex 1 and 2
Viral cause of heterophile-antibody positive mononucleosis
Epstein-Barr
Causes distinctive gray oral spots followed by a maculopapular rash on the body
Measels
This (-) RNA virus is a viral superinfection that causes cirrhosis
Hep D
Respiratory virus that cuses a 3 day rash that is lighter in color than measels rash
Rubella
This virus produces cytoplasmic inclusions known as Guarnieri bodies
Bariola
This viral disease can be prevented by vaccination after virus acquisition
Rabies
Causes croup and a cough that sounds like a seals bark
Parainfluenza
Major cause of 1 day gastroenteritis, common on cruise ships
Norovirus
DNA virus that causes clusters of benign pink skin tumors with central indentations
Molluscum contagiosum
This virus denudes the lungs and allows for secondary bacterial pneumonia
Influenza
Lacy, reticulated, macular erythema
Parvovirus B19
This (+) or (-) ssDNA is associated with pericarditis
Parvovirus B19
Epidermodysplasia varruciformis patients which are also susceptible to squamous cell carcinoma
HPV 5 and 8
Oropharyngeal squamous cell carcinoma
HPV 16
Benign HPV head and neck tumors
HPV 6 and 11
Immunocompromised patients reactivate viruses causing UTIs/viremia and CNS infection.
Polyomaviruses BK and JC
Transforms astrocytes and kills oligodendrocytes leading to progressive multifocal leukoencephalopathy
JC Polyomavirus
Swimming pool conjunctivitis
Adenovirus
Acute viral gastroenteritis with watery diarrhea
Adenovirus serotypes 40-42
Acute viral respiratory disease that is high in military recruits
Adenovirus serotypes 4 and 7
Adenovirus serotypes that primary infect KIDS with respiratory illnesses
Adenovirus serotypes 1, 2, 3, 5, and 6
Only hepatitis virus that encodes DNA instead of RNA
Hep B
DNA virus that encodes reverse transcriptase and replicates through a circular RNA intermediate
Hep B
Detection of both HbsAg and HebAg in the blood indicates an ongoing active infection
Hep B
Viral-mediated jaundice, dark urine, pale stools
Hep B
Herpes simplex type that becomes latent in B cells
EBV
Herpes simplex viruses that becomes latent in neurons
HSV and VZV
Herpes simplex virus becomes latent in lymhocytes
CMV
Has a tegument containing proteins and enzymes that facilitate replication in non-growing cells
Herpesviruses
Gingivostomatitis, keratoconjunctivitis, encephalitis and herpetic whitlow
HSV-1
Virus becomes latent in the trigeminal nerve ganglia
HSV-1
Virus becomes latent in the sacral nerve ganglia
HSV-2
Genital herpes, neonatal infections, meningitis, and herpetic whitlow
HSV-2
Virus that is transmitted to humans through monkey saliva, usually causing fatal encephalopathy
simian HSV
Produces cells with large, purple intranuclear inclusion bodies surrounded by a halo resembling owl eyes
Cytomegalovirus (CMV)
Virus responsible for the failure of many kidney transplants, as well as retinitis and pneumonia
Cytomegalovirus (CMV)
Common viral triggers of Guillain-Barre syndrome
Cytomegalovirus (CMV) and Epstein-Barr Virus (EBV)
Prototype for these viral infections is acyclovir
Herpesvirus
Infected cells have cytoplasmic inclusion bodies called Guarnieri bodies
Variola virus--Poxvirus
Broad class of RNA viruses that are all helical, enveloped, and carry virus associated RNA-dependent RNA polymerase
(-) sense ssRNA viruses
Three (-) sense ssRNA families with segmented genomes (OBA)
Orthomyxoviridae
Bunyaviridae
Arenaviridae
This viral envelope glycoprotein promotes fusion of the viral and host cell membranes
Fusion (F) protein
Viral envelope glycoprotein inserted into cell membrane causes syncytia formation.
Fusion (F) protein
Viral envelope glycoproteins (2) binds sialic acid receptors
Hemagglutinin-neuraminidase (HN)
Hemagglutinin (H)
Paramyxovirus with H and F glycoproteins
Measles (Rubeola)
Two Paramyxoviruses with F and combined HN glycoproteins
Mumps and Parainfluenza
Paramyxovirus with only F glycoprotein
Respiratory syncytial virus (RSV)
This (-) ssRNA virus starts with CCCP=cough, coryza, conjunctivits, and photophobia
Measles (Rubeola)
Koplik spots
Measles (Rubeola)
Virus presents with stridor, seal-bark cough, and subglottal swelling
Parainfluenza virus
Virus is localized to the respiratory tract and induced syncytia
Respiratory Syncytial Virus (RSV)
Most common cause of lower respiratory tract infection in young children
Respiratory Syncytial Virus (RSV)
Second most common cause of lower repiratory tract infection in young children
Metapneumovirus
Flying fox reservoirs, cause flulike symptoms, seizures, and coma.
Nipah
Hendra
Bullet-shaped virus transmitted mostly by bat contact in USA
Rabies
Animal bite site showing pain, itching, and paresthesia, along with systemic symptoms
Rabies
Foot and mouth disease
Vesicular stomatitis virus
Filoviruses that causes extensive cell tissue necrosis
Ebola
Marburg
Interferons and cytokines peak at the same time in this virus and cause the classic 'flu' symptoms
Influenza A
The only Bunyavirus carried by rodents
Hantavirus
Two (-) RNA and one ambisense strand
Bunyaviruses
Hemorrhagic Fever with Renal Syndrome; fever, hemorrhage, hypotension, and renal failure.
Hantaviruses
Segmented circular genomes; one (-) RNA and one ambisense
Arenaviruses
This (-) RNA virus is carried by sheep and horses and spreads through the CNS
Bornavirus
Only pathogen (and it's (-) RNA) to use host cell CNA-dependent RNA polymerase to make mRNA and RNA copies of the genome
Hep D Deltavirus
Only human virus (and it's (-) RNA) to forme an RNA ribozyme which cleaves many joined RNA genome copies into monomers)
Hep D Deltavirus
Proteolytic cleavage in the GI activates virus, producing an infectious subviral particle.
Rotavirus
Class of RNA viruses with linear, nonsegmented genomes.
(+) ssRNA viruses
Class of viruses that carry code for RNA dependent RNA polymerase, but not in the mature virion.
(+) ssRNA viruses
(+) ssRNA genome that makes (-) ssDNA with a reverse transcriptase
Retroviruses
Fecal-oral infection that travels from the larynx to the GI and then gains access to the brain by infecting skeletal muscle.
Poliovirus
This mosquito-borne (+) ssRNA virus causes a hemorrhagic fever in babies with maternal antibodies, or individuals with antibody from a previous infection.
Dengue virus
This virus binds to surface receptors on lymphocytes, outside of its target organ, and also inhibits apoptosis, making it very persistent.
Hep C
20% mortality for pregnant women in their 3rd trimester due to fulminant hepatitis.
Hep E, Hepevirus
Class of virus that has surface glycoprotein spikes that force the envelope to wrap tightly
Togavirus
This virus causes cataracts, mental retardation and deafness in fetuses when their mothers are infected.
Rubella
Virus has E2 proteins that are the target of neutralizing antibodies.
Coronaviruses
Diploid RNA viruses that encode RNA-dependent DNA polymerase (RT) and replicate through a DNA intermediate.
Retroviruses