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55 Cards in this Set

  • Front
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Acute Respiratory Disease / common cold

Signs and Sx.
Sore throat, Runny nose, congestion, cough, CHILD: 7-10 days, ADULTS: 2-5 days.
Acute Respiratory Disease / common cold

Etiology
Rhinovirus, Coronavirus. Those with LRI too (like bronchiolitis/ pneumonia) RSV, Human metapneumovirus, influenza, adenovirus, parainfluenza (croup), human bocavirus mycoplasma, chlamydia
Acute Respiratory Disease / common cold

Complications
Lower Respiratory Infections, Otitis, Sinusitis, Exacerbations (asthma, COPD)
Acute Respiratory Disease / common cold

Dx
Presumptive. Swab, Rapid test (ELISA), RSV, Influenza.
Acute Respiratory Disease / common cold

Tx
None proven (such as AB, Histamines, decongestants or Zinc)

RSV: ribavarin
Flu A: amantidine/rimantidine
Acute Respiratory Disease / common cold

Prevention
Isolation, handwashing
Acute Respiratory Disease / common cold

Epidemiology
Seasonal. Children: 6 -10x per year (direct contact spread)

>50% of all sick leave
Pharyngitis
"Strep throat, mononucleosis"

S/Sx
Fever, sore throat, dysphagia, pharyngeal erythema, exudates, Lymphadenopathy, nausea/vomiting with Group A Strep. 3-6 days even w/o Tx.
Pharyngitis
"Strep throat, mononucleosis"

Etiology
If non-exudative --> see common cold

Exudative: adenovirus (pink eye)
EBV (mono)
Strep pyogenes Group A Strep (but only 1/3 exudate)
Pharyngitis
"Strep throat, mononucleosis"

Complications
Mono: Burkitts, nasopharyngeal CA, splenic rupture.

Group A Strep: Scarlet fever, rheumatic fever, glomerulonephritis, abscess, otitis, pneumo.
Pharyngitis
"Strep throat, mononucleosis"

DX
EBV: mono spot test (heterophile test)

GAS: Rapid strep test and culture, Antistreptolysin O, streptozyme
Pharyngitis
"Strep throat, mononucleosis"

TX
Mono: supportive, steroids if SEVERE inflammation.
GAS: PCN x 10 days
Pharyngitis
"Strep throat, mononucleosis"

Prevention
Tonsillectomy. Check others in household.
Pharyngitis
"Strep throat, mononucleosis"

Epidemiology
GAS: 6-12 year old, children assympt carrier in 50% of cases.
Otits Media.
Tube blockage, virus. + nasopharynx infection = pressure and pain.

S/Sx
URI, otalgia, drainage, decreased hearing, fever, TM bulding lose landmarks, red, blebs on TM = virus.
Otits Media.
Tube blockage, virus. + nasopharynx infection = pressure and pain.

Etiology
1/3 sterile
1/3 strep pneumo
1/6 H. flu (untypeable)
1/6 other.

Chronic: pseudomonoas, staphylococcus, anaerobes.
Otits Media.
Tube blockage, virus. + nasopharynx infection = pressure and pain.

Complications
Perforation, hearing loss, learning disability, mastoiditis, meningitis.
Otits Media.
Tube blockage, virus. + nasopharynx infection = pressure and pain.

Dx
Presumptive, tympanocentesis, myringotomy.
Otits Media.
Tube blockage, virus. + nasopharynx infection = pressure and pain.

Tx
Amoxicillin, cephalosporin, TMP-SMX (TRIMETHOPRIM/SULFAMETHOXAZOLE) Myringotomy relieves
Otits Media.
Tube blockage, virus. + nasopharynx infection = pressure and pain.

Prevention
Decongestants, vaccination, allergy tx, tubes.
Otits Media.
Tube blockage, virus. + nasopharynx infection = pressure and pain.

Epidemiology
Children (the sinusitis equivalent) 2/3 before second birthday.
Sinusitis
Virus/allergy/anatomy = obstruction. Bacterial infection, pressure, pain.

S/Sx
Sinus pain, headache. Fever, rhinorrhea, otitis media. No transillumination (opaque)
Sinusitis
Virus/allergy/anatomy = obstruction. Bacterial infection, pressure, pain.

Etiology
1/3 sterile, 1/3 strep penumo, 1/6 H. flu, 1/6 other. Chronic: psudomonas (otitis) Staphylococcus, anaerobes.
Sinusitis
Virus/allergy/anatomy = obstruction. Bacterial infection, pressure, pain.

Complications
Chronic sinusitis, osteomyelitis, meningitis (if anatomic problem)
Sinusitis
Virus/allergy/anatomy = obstruction. Bacterial infection, pressure, pain.

Dx
---
Sinusitis
Virus/allergy/anatomy = obstruction. Bacterial infection, pressure, pain.

Tx
AB (strep & h.flu)

Chronic:
AB (Staph & Anaerobe)
Sinusitis
Virus/allergy/anatomy = obstruction. Bacterial infection, pressure, pain.

Prevention
Decongestants, allergy tx, correct anatomy.
Sinusitis
Virus/allergy/anatomy = obstruction. Bacterial infection, pressure, pain.

Epidemiolgy
Adults (the otitis equivalent), with URI's allergies.
Epiglottitis

S/Sx
Preceding URI, sore throat, barky cough, stridor, choking senstaion, drool. Chills, fevers, TOXIC swollen epiglottis and neck, sitting up and leaning foward.
Epiglottitis

Etiology
Parainfluenza, H. flu type b, GAS (strep pyogenes), strep pneumo
Epiglottitis

Complications
Airway obstruction
Epiglottitis

Dx
Blood cultures (bacteremia), Lateral neck Xray, thumb sign on there, Throat cultures, Careful do not do gag reflex.
Epiglottitis

Tx
Establish airway (have emergency tracheostomy ready), lateral neck Xray, AB
Epiglottitis

Prevention
Vaccine (H flu B)
Epiglottitis

Epidemiology
Non-imunized kids, adults when poorly immunized.
Pertussis (WHOOPING COUGH), 3 stages.

S/Sx
Catarrhal (rhinorrhea)
Paroxysmal (cough/whoop)
Convalescent (get better)
Pertussis (WHOOPING COUGH), 3 stages.

Etiology
Bordatella pertussis
Pertussis (WHOOPING COUGH), 3 stages.

Complications
Respiratory compromise
Pertussis (WHOOPING COUGH), 3 stages.

Dx
Clinically, culture fluorescent Ab strain by PCR
Pertussis (WHOOPING COUGH), 3 stages.

Tx
Supportive, Erythromycin
Pertussis (WHOOPING COUGH), 3 stages.

Precention
The P in DPT for babies
The P in DTap for booster shots
Pertussis (WHOOPING COUGH), 3 stages.

Epidemiology
Non-immunized adults with waning immunity cough 3-5 weeks (!)
Diphtheria
Throat, heart, nerves.

S/Sx
Pharyngitis, LAD, Fever, Malaise, Gray pseudomembrane in throat
Diphtheria
Throat, heart, nerves.

Etiology
Coryneacterium diphtheria, produces toxin that attaches to EF2.
Diphtheria
Throat, heart, nerves.

Complications
Myocarditis, heart failure/arrhythmia. Myelin degeneration: nerve palsy/paralysis.
Diphtheria
Throat, heart, nerves.

Dx
Clinically, culture.
Diphtheria
Throat, heart, nerves.

Tx
Antitoxin, PCN, supportive
Diphtheria
Throat, heart, nerves.

Prevention
the D in DPT vaccine
the D in DTap booster shots
Diphtheria
Throat, heart, nerves.

Epidemiology
Nonimmunized, always investigate all close contacts.
Haemophilus Influenza
(blood loving) (causes pneumonia after influenza)

Think TYPE B.

Structure
Gram NEGATIVE.
Pleomorphic (coccobacillary), non-motile, non-spore forming
Haemophilus Influenza
(blood loving) (causes pneumonia after influenza)

Think TYPE B.

Virulence Factor
Capsule (6 types)
Avoids phagocytes, used to identify type.

B is the most important.
Haemophilus Influenza
(blood loving) (causes pneumonia after influenza)

Think TYPE B.

Epidemiology
Otitis, sinusitis, epiglotitis, pneumonia, meningitis, sepsis, 2ndary to viruses.
Haemophilus Influenza
(blood loving) (causes pneumonia after influenza)

Think TYPE B.

Immunity
Via Ab to capsular polysacch. Infants susceptible after maternal Abs gone (6 months) - < 2 yrs = poor response to polysacc antigens
Haemophilus Influenza
(blood loving) (causes pneumonia after influenza)

Think TYPE B.

Prevention
H flu B:
Capsular vaccine

PROBLEM:
Must be >2 yrs old for response. but 6 months to 24 months, highest risk for infection

SOLUTION: conjugate vaccines (link PRP = polyribitol phosphate to proteins, give enhanced immunogenicity. 3-4 injections starting at 2 months, now 95% decrease invasive H flu b).
Haemophilus Influenza
(blood loving) (causes pneumonia after influenza)

Think TYPE B.

Other details
Growth factors required:
(think a mother goes to a 5 and dime when her child has the flu)
V: NAD from lysed RBCs
X: Hematin