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14 Cards in this Set
- Front
- Back
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All sporulating species are opportunistic except
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Bacillus antrhacis
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What bacteria has beneficial effects such as producing detergent enzymes, or enzymes for food production
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Bacillus subtilus
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What bacillus species causes vomiting/nasuea?
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Cereus
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What causes botulism?
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Clostridium botulinum's TOXIN
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What bacteria causes gas gangrene?
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Clostridium histotoxic
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What bacteria causes Abx associated GI disease?
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Clost. dificile
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What part of a bacteria helps deliver drugs to the CNS?
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The B- part of the Tetanus toxin
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How are bacillus cereus harmful?
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secrete an eneterotoxin in their vegetative state
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Explain the bacillus anthracis toxin
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B that is the Protective Antigen
A1 that is the Lethal factor A2 that is the edema factor B binds antrhax receptor Cleaved B forms heptamer for A1 or 2 to enter |
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What are the 2 A parts of the antrax toxin? what does each do?
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A1 is LF - cleaves MAPKK
A2 is EF - makes cAMP |
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Describe the botulism toxin
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B binds neurons @ NM junction
A is Zn-endopeptidase which binds snares, therefore AcH is not released |
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Describe the tetanus toxin
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B binds neurons @ NM INHIBITORY junction
A is Zn-endopeptidase which binds snares, therefore AcH is not released |
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What is often found in honey that is why it should not be given to infants?
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Clost. botulinum
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Clostridium dificile is found in hospital settings but also in 10% of the human pop's normal flora. Describe it's toxin
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IT's entero/cytotoxins are AB type which UDP-Glucosyl transferase target GTPase, and de-regulate the synthesis of actin cytoskeleton
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