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20 Cards in this Set
- Front
- Back
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Describe Streptococcus in terms of
Gram property Motility Spore Location O2 requirement |
Gram property - +
Motility - NON Spore - NON Location - skin/mucous O2 requirement - facultative anaerobes |
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Describe Strep in terms of
Catalase property Possible hemolytic properties |
Catalase - NEGATIVE
Hemolytic: Alph - green hue Beta - COMPLETE lysis - clear Gamma - No lysis |
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What are 2 adherence factors of Strep?
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M/F protein - binds fibronectin
Lipoteichoic Acid - binds epith cells |
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What are 4 Immunoavoidance factors of Strep?
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M-protein: binds Fact H, to degrade C3b, so no C3b-Bb convertase
C5a Peptidase - Prevents chemotaxis of n-phils/phags M-Like Protein - bind to FC of IgG/IgA - coats cell in HOST protein Hyaluronic Acid Capsule - Similar to HOST CT |
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How is Rheumatic Fever or Glomerulonephritis ID'd?
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Presence of Streptolysin O, which is O Labile
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How do Streptolysin O and S differ?
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O is O labile, S is O stable
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What does SpeA/B/C do?
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Induces TOXIC SHOCK by activating t-cells for cytokine release, causing Rash from MHC2 interaction
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What is the Erythrogenic Toxin?
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Phage medeiated toxin, causes Scarlet Fever
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What does Streptodornase do?
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iT BREAKS DNA - reducing pus viscosity
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What does Hyaluronicase do?
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Helps Strep Spread
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What does streptokinase do?
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Blood clotting, helps to SPREAD RAPIDLY
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WHat 5 conditions can Pygoenes cause?
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Pharyngitis
Pyoderma Cellulitis Necrotizing Fascitis Toxic Shock |
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What are the 2 ways to idagnose Strep infection?
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Direct: blood agar shows hemolysis
Indirect - Abs of streptococcal enzymes |
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How is strep pyogenes treated?
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With Penicillin G primarily
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How is strep Pyogenes NOT treated?
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Aminoglycosides
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Strep. pneumoniae
1 G property? 2 Location 3 when it becomes a problem |
1 - G+
2 - Nasopharynx 3 - ear - otitis media Sinus - sinusitis meninges - meningitis lungs - pneumonia |
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4 VF's of Strep Pneumoniae
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Polysac/Antiphag capsule
Pneumolysin - slows cilia IgA Protease Neuraminidase - decreases mucous viscosity |
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What are the 2 ways to treat strep pneumoniae?
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1 - fluoroquinones/vancomycin or
2 - Vaccine that converts Polysacc to T-cell Ag |
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What is the only species of Strep that carries Group B Antigen?
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Agalactiae
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Strep Agalactiae
Hemolytic property? Location? VF? Treatement? |
Beta hemolytic
Low GI tract Polysacc capsule Treated w/ Penicillin |
