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17 Cards in this Set
- Front
- Back
What is the key cell of Immediate-phase of inflammation?
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Mast cell
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The mast cell is rich in what 2 vasoactive substances?
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heparin and histamne
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Complement is dependent on ____proteins from the _____(organ)
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serum
liver |
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Which is our main opsonizing protein?
C3b C3a/C5a C5b/C6/7/8/9 C2a |
C3b
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which sends signal to increase migration of phags/mast cells?
C3b C3a/C5a C5b/C6/7/8/9 C2a |
c3a/c5a
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which is the MAC
C3b C3a/C5a C5b/C6/7/8/9 C2a |
c5b/6/7/8/9
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which give pai/vascular permeability
C3b C3a/C5a C5b/C6/7/8/9 C2a |
c2a
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whether complement uses classical or alternative path, they both end up with what
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C3 convertase cleaving C3
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what is the crucial cell of the acute phase of inflammation?
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neutrophil
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transendothelial migration relies on the binding of ____cells and _____s.
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endothelial cells
neurtophils |
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transendothelial migration relies on
endoth cells_____ and ____on neurtophils |
surface protein
ligands |
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For ______to happen, endoth cells must express ______E,P, which is iniitated (eg) by_____. neutrophils must express_____ _____s, which then bind reversibly
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rolling adhesion
selectins histamine glycoprotein ligands |
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For_____to happen, a leukocyte expresses a ______ and endothelium express _____.
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tight binding
integrin integrin |
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One way of phagocytosis is oxidative killing, which generates superoxides from _____.
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nadph oxidase
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4 outcomes of inflammation
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resolution
scar abscess chronic |
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which are characterisci of acute inflammation?
pmn lymphocytes plasma cell macphages |
pmn
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which is characteristic of chronic inflammation
pmn lymphocyte plasma cell macphages |
lymph
mac plasma |