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8 Cards in this Set
- Front
- Back
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What type of immunity is the principle type against extracellular bacteria?
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Humoral immunity
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What is can LPS cause in its most serious effect? How does it cause this?
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If it gets into blood it cause SEPSIS SHOCK - which is intravasc coagulation, hypoglycemia, cardio failure
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What do superantigens do?
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They are an enterotoxin that binds TCR and APC (@MHC) and cause excessive proliferation (until death)
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What is the innate reaction against intracell bacteria?
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Neutros and macros produce IL12 and IFNy to stimulate NK cells
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Whta is the adaptive immunity reaction against Intracell bacteria?
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T-cell mediated, CD4 cells become TH1 and TH2 Cells
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How do neutrophils act in innate immunity vs. Fungi?
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Secrete REACTIVE O2 intermediates
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What is SAP and how is it used to help fungi survive vs. innate defense?
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A protease that inactivates AMPs
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Type 1 IFN's and NK cells are principal mechanism for innate immunity to what?
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Viruses
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