Micro-Qbank

Front 1

ELEK test

Back 1

tests for toxin production by Coryne diphth

Front 2

medium of choice to Dx Neisseria

Back 2

Thayer-Martin==>medium of choice for growth of Neisseria from sites with normal flora (not CSF)

simple chocolate agar==>medium of choice to Dx meningococcal meningitis (N men)

Front 3

lecithinase

Back 3

enzyme prod by C perf that damages cell membranes

Front 4

stain for Pneumocystic jiroveci

Back 4

methenamine silver

Front 5

suppurative cholangitis caused by

Back 5

-Ascaris lumbricoides
-liver flukes: Clonorchis sinesis & Fasciola hepatica

Front 6

EF-2

Back 6

Elongation Factor 2 for TRANSLATION elongation

tbus, toxins like C diph toxin that inhibit EF-2 are actually inhibiting translocaton elongation

Front 7

rat-bite fever

Back 7

2 forms:

1. Streptobacillus MONliformis
-"Haverhill fever form"
-in U.S.
(G- bacillus)

2. Spirillium minus
-"Sodoku form"
-in Japan

*visualize MONica with Strep throat (but it's G-) stabbing a rat with a "SPIRE" from a Japanese Buddhist temple

Front 8

cat scratch dz

Back 8

Bartonella henselae

Front 9

bacillary angiomatosis
-desc
-et

Back 9

=vascular proliferative dz involving skin, sub-q tissue, and bone in imm-s pts

-caused by Bartonella henselae & Bartonella quintana

Front 10

most important pathogenic trait of E. coli

Back 10

P-pili (=pilus adhesin associated with pyelonephritis)

Front 11

Toxins Stx-1 and Stx-2 produces by what?

Back 11

=Shiga toxins

produced by Shigella & E coli

Front 12

aztreonam

Back 12

monobactam (diff structure from penicillin, so can gie to ppl allergic to penicillin)

-not B-lactamase resistant
-Tx G- but not G+

Front 13

mech of infxn of Pseudomonas

Back 13

Pseudomonas produces Exotoxin A, which ADP-ribosylates (thus inhibitating) EF-2
==>elongation during protein translation

Front 14

MOA of cephalosporins

Back 14

~ penicllins:

bind PCP's==>prevent cell wall synthesis

Front 15

quinolone antibiotics
-ex
-MOA

Back 15

-ex. ciprofloxacin
-MOA: inhibit DNA gyrase

Front 16

G+ coccus that grows on mannitol salt agar

Back 16

Staph

Front 17

why is Histo not easily transferred from person to person?

Back 17

intracellular

Front 18

"honey-crusted lesions"

Back 18

=impetigo

MCC=GAS
2nd MCC=SA

Front 19

forms fibrous clot in animal serum

means what?

Back 19

coagulase +

Front 20

how does SA evade phagocytosis?

Back 20

Protein A binds Fc of IgG==>prevents opsonization

Front 21

which bacteria gain fxn from lysogenic phage genome?

Back 21

C. botulinum (exotoxin)
SA (erytrogenic toxin)
Salmonella (O antigen)

Front 22

inoculating sample of organism into animal serum ("germ tube test") yields pseudohyphae.

Dx?

Back 22

candida albicans

Front 23

what organisms are catalase +

Back 23

SA
Pseudomonas
Candida
Aspergillus
Enterobacter

Front 24

Group D Strep

-ex
-who is susceptible
-how Dx

Back 24

an example is Strep bovis

-ppl with colon dz (i.e. colon CA) are suspectible to Strep bovis bacteremia and endocarditis

-Dx by seeing cell wall carbohydrate composed of glycerol teichoic acid

Front 25

diabetic with lesion that has black necrotic center

-et
-toxin

Back 25

caused by Pseudomonas (see my pic of Kate in FA)

-alpha toxin: inhibits EF-2 (target=liver cell)
==>inhibits protein elonation

Front 26

what bug agglutinates human O+ RBC's in the cold?

Back 26

Mycoplasma pneumoniae

(cold hemagglutins)

Front 27

what bug causes agglutination of Strep salivarius strain MG?

Back 27

Mycoplasma pneumoniae

(Strep salivarius strain MG= Strep MG agglutins)

Front 28

what normally colonizes the vagina of a woman during:

-pre-puberty?
-childbearing age?

Back 28

-pre-puberty: Staph epi

-childbearing age:
Lactobacillus
Candida
Strep

Front 29

what AB taken by pregnant mom causes newborn to develop abdominal distension, pallid cyanosis, and irregular resp?

Back 29

Chloramphenicol

("gray baby syndrome" [gray=cyanotic]: ridic pic-- chlorine pouring into bone and gray baby)

Front 30

can you a pregnant woman safely take aztreonam

Back 30

yes

Front 31

in burn victims, what does Pseudomonas produce to cause sepsis & hemorrhagic/ulcerated over the burns?

Back 31

elastase (breaks down elastins AND prevents neutrophil chemotaxis)

Front 32

pt with Hx of chronic bloody diarrhea presents with large, tender liver.

bug?

Back 32

Entamoeba histolytic (can cause dysentery, peritonitis, or liver abscess)

Front 33

pharyngoconjunctivitis spread by swimming pools

Back 33

adenovirus

Front 34

MCC Toxoplasmosis

Back 34

poorly cooked pork (not cats!)

Front 35

how does N. gonorrhea evade phagocytosis

Back 35

pili (not capsule)

Front 36

how does N. gonorrhea evade the immune system?

Back 36

antigenically variable pili

Front 37

#1 and #2 populations most susceptible to PCP?

Back 37

#1 AIDS
#2 premature infants

Front 38

tinea pedis

-findings on KOH mount

Back 38

branching, septate hyphae with arthroconidia

Front 39

Sporothrix schenckii

-findings on KOH mount

Back 39

branching hyphae with rosettes of conidia

Front 40

sporotrichosis

-findings on KOH mount

Back 40

budding yeasts

Front 41

KOH mount shows short, curved hyphae and round yeasts

Back 41

="spaghetti (hyphae) and meatball (round yeats)"

Malassezia furfur (==>pityriasis versicolor & dandruff)

Front 42

daycare center or military

>20 bloody diarrhea episodes per day

Back 42

Shigella

Front 43

fxn of recA gene in bacteria

Back 43

recA= recombinase A gene

-recA is required for homologous recombination b/c recA is what integrates new DNA into recipient DNA piece

required for:
-transformation
-generalized & specialized transduction
-Hfr to F- conjugation

but NOT for F+ to F- conjugation

Front 44

cat scratch disease

Back 44

Bartonella henselae (G- rod)

Front 45

11 y/oi girl with recurrent URTI has tonsils with granules that have G+ center and numerous branching filaments at periphery.

dx?

Back 45

Actinomyces israeli

Front 46

person with recurrent diarrhea has stools that contain cysts w/multiple nuclei

Back 46

entamoeba histolytica

Front 47

why is chlamydia an obligate intracellular parasite?

Back 47

b/c it can't make ATP

Front 48

G- oral flora that can cause subacute bacterial endocarditis after dental procedures

Back 48

"HACEK":


Haemophilus aphrophilus
Actinobacillus actinomycetemcomitans
Cardiobacterium hominis
Eikenella corrodens
Kingella kingae

Front 49

woman visits woods near beach in the Northeastern U.S. and develops fever, chills, H/A

blood smear demonstrates protozoa within erythrocytes

Dx?

Back 49

Babesia microti (protozoa in maltese cross: cross or X-shaped)

(ridic pic: p. 245)

Front 50

gastric CA d/t H pylori is associated with what gene?

Back 50

CagA=cytotoxin associated gene A

Front 51

which layer of the epithelium does HPV affect?

Back 51

stratum basale

Front 52

corkscrew motility

Back 52

Trichomonas

(mneum: you can get Trichomonas from "screwing"
==>corkscrew motility)

Front 53

white spots on bright red background on buccal mucosa

Dx?

Back 53

measles

(white spots=Koplik spots)

Front 54

what virus can cause post-infectious (~1 week after infxn) encephalomyelitis?

-findings on CNS biopsy?

Back 54

measles

-CNS biopsy shows pervenous microglial encephalitis with demyelination

Front 55

pharyngoconjunctivitis spread b/w ppl swimming in same swimming pool

Back 55

adenovirus