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40 Cards in this Set

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**which organisms overlap bw causes of UTI and STD
gonococcus
chlamydia
they cause.....
urethritis but are transmitted by sex
3 reasons why UTI are more frequent in women than men
- name common 6 common organisms and they're way of infection
- which one is the most common
1-shorter urethra, prevalent in 20-50y/o
2-unique receptors on uroepi cells
3- men have anti-microbial prostatic secretions.
E.coli,
Proteus,
Enterobacter,
Klebsiella, Enterococcus,
Staph.(esp saprophyticus)
they migrate from the skin or GI
the most common is e-coli
this advanced condition affecting the GU tract typically present w hypotension and low flank pain
- what condition is this
- other presenting symptoms
pyelonephritis
also may pw fever, bacteremia, sepsis
list the most common organisms that cause prostatitis
- gram negatives
- and which gram positives?
gram neg (-)
enterics primarily:
- MC- e.coli
- ST--- klebsiella, proteus
- least---pseudomona, enterobacter, serratia

gram (+) ?----->
rare except for enterococci
A patient presents w fever, dysuria, frequency, BOO, and a tender prostate
- diagnosis
- precautions in PE
acute prostatitis
avoid prostatic massage bc it may induce bacteremia
male pt with h/o BOO now p/w LBP, low grade fever, myalgias, arthralgias...
- most likely condition
- this patient would be at risk for what, as a complication of his condition
chronic prostatitis
it may be a reservoir for recurrent UTI.s
ideal diagnostic modality for prostatitis
- treatment approach
urine
blood culture
or both
often empirically to include coverage for most enteric derived bacteria
the most common cause of NON-gonococcal urethritis
- way for transmission
chlamydia
causes an atypical form of urethritis that arises from an STD
young sexual active female presents w frequency, urgency and disuria. She c/o copious d/c. Her gram stain is negative, blood cultures in chocolate and mcconkey agars are also negative.
- what would be the most likely organism
- best diagnostic modality
chlamydia infection causing urethritis.

its DOES NOT grow on choco or mconkey.
GIEMSA analysis of D/C could be (+) stains protein and nucleic a.

serology or molecular tech useful
clinical symptoms of UTI
dysuria, frequency, urgency in 50-60%
lower flank pain: kidney/bladder
inguinal pain: bladder, urethra, prostate.
details requested in UA for diagnosis of UTI
UA
PMNs and bacteria
gram stain or acid fast stain
culture on blood/choco/mconkey agars
- gram stain isolates
UA non specifics, look for:
blood
elevated protein levels
if a organism grows on mcconkey agar, what type of microorganism is it?
what further studies are needed for differentiation?
most likey enteric gram negative
lactose fermentation
most common lactose fermenters
- appearance
e.coli
klebsiella
enterobacter
colonies appear pink purple
TSI agar/mcconkey
what would be a significat value of CFU in urine culture, when would this rule not apply
10 to the 4- 10 to 5 cfu per ml.
acute dysuria (sp type)
indwelling catheter
the most common enteric bacteria
gram ? microorganism that is methyl red +,
indole +,
lactose fermenter
gram +
e-coli,
this property is specific to Proteus and Klebsiella
UREASE +
gram +
catalase -
utilizes bile and esculin
enterococci
Non enteric a/w cystitis and is more prevalent in europe
staph. saprophiticus
non enteric bacteria
coagulase -
novobiocin resistant
staph. saprophiticus
considered one of the most motile microorganisms, sulfur producer
proteus
micoorganism that is a/w kidney stone formation,
urease and sulfur producer,
non lactose fermenter
highly motile
proteus
male pt p/w dysuria, copious d/c w organisms found inside and outside neutrophils.
gram (-) diplococcus:
Neisseria gonorrhae
female p/w mild dysuria, h/o multiple sexual partners.
gram stain of vaginal exudate shows a pink gram (-) kidney bead shaped cocci
gonorrhea
a female pt presented with urethritis an mild d/c, no other symptoms. condition resolved without treatment. What risk does this patient carry?
silent carrier that continues to spread the infection
extragenital syndromes of gonorrhea
proctitis
pharyngitis
female patient presents w arthritis , skin pustules, mainly on the left knee. she recalls an episode of PID in the past
gonorrhea extragenital disease, GC now is present in the blood,also presents w PID alone
a physician is concerned in the management of this microorganism culture. he request specifically chocolate agar, rapid transport to the lab. The organism is incubated under fastidious microaerophilic conditions. whats the most likely organism affecting the patient from which the sample was taken
N. gonorrhea
grows in moist areas of thebody
this organism does NOT like air
is oxidase +
ferments ONLY glucose: this confirms the diagnosis
N. gonorrhea
this factor determine the virulence of N. gonorrhea, it prevents the death of the PMN
the Pili
- strains w pili are more infectious
- they help the gonococcus attach to the mucosa
- possible role in vaccine development
a patient was diagnosed w gonorrhea after treatment he asks if hes protected against contracting the condition again?
yes he is at risk because even though there is antibody produced it is not effective in producing immunity.
male pt w dysuria, copious purulent d/c developes 2-6 days after sexual contact, gram stain shows a gram (-) diplococcus inside PMN
n. gonorrhea
it is the most common reported STD and the most common cause of non-gonococcal urethritis
chlamydia trachomatis
a female high school senior presents w light/clear d/c she mentioned it looked like milk, and in small amount. She is sexually active from a high socio-economical status. the progression of this disease can lead to infertility , PID
chlamydiosis
young female high school students admits to being sexually active, p/w discharge that is clear. gram stain is negative, no bacteria is seen in specimen, but found some inclusion bodies and when iodine was added it stained glycogen.
DFA shows cytoplasmic inclusions.
this organism is visualized inside host cells after GIEMSA staining.
C.trachomatis a obligate intracellular pathogen so called "energy parasites" they need the ATP of the host cell to survive.
what are the 4 stages of the life cycle of C.trachomatis
1-elementary body: extracell inactive
2- reticulate body element (IC growing)
3- inclusion body (growing RB that mature inside host cell)
4- Intracell life: 48-72h.
--it acts almost like a virus
this organism can infect the kidney and testicles, org are culturable from urine or tissue bx; MUST culture on LJ agar.
M. tuberculosis
LJ agar
AF stain
+PPD
infects kidneys during acute systemic phase, cultures from urine, gram (-) rod, NON lactose fermenter after mconkey
Salmonella typhi
infection acquired through the skin, reach kidneys and bladder, diagnosis made by observing eggs in urine by microscopy
schistosome: egg w terminal spine
causes immune mediated damage to the kidney, h/o soar throat. live bacteria not present at any of these sites. diagnosis made by titers
group A strep.
ASO high titers
organisms associated w catheterization
E.coli
Proteus
Pseudomona
Klebsiella
Serratia
Staph. spp
Enterococcus
Candida a.