Micro Nath Respiratory System Uri

Front 1

Rhinorrhea, red throat, and nasal pus are caused by

Back 1

Rhinoviruses

Front 2

Rhinoviruses and enteroviruses belong to picornavirus family, but
the rhinoviruses differ from enteroviruses on

Back 2

Growth at 22d C/noninvasive

Front 3

Rhinovirus receptor in the nasal passages and upper
tracheobronchial tree is

Back 3

ICAM-1

Front 4

Rhinovirus, influenza, parainfluenza, coronavirus, RSV, metapneumovirus, and adenovirus all cause

Back 4

Upper-respiratory infections

Front 5

Sinusitis, otitis, laryngitis, exacerbations of bronchitis and asthma
are mostly secondary to

Back 5

Viral URIs

Front 6

In HEENT, Streptococcus pneumoniae, non-typable Haemophilus
influenzae, Moraxella catarrhalis all cause

Back 6

Acute otitis media (AOM) &
sinusitis

Front 7

AOM and sinusitis are empirically treated with amoxicillin +
clavulanate. Why use clavulanate?

Back 7

Haemophilus and Moraxella
are beta-lactamase producers

Front 8

Cause of pharyngeal pain, dysphagia, fever; red throat + purulent exudate that responds to penicillin

Back 8

Streptococcus pyogenes (aka:
Group A Streptococcus)

Front 9

GABHS is differentiated from GBBHS by what? ]

Back 9

Bacitracin sensitivity

Front 10

Common mode of acquisition of URI due to Streptococcus
pyogenes?

Back 10

Infective droplets

Front 11

Major virulence factor (with anti-phagocytic function) of Streptococcus pyogenes

Back 11

M protein fibrils

Front 12

Damage in posterior pharynx and tonsils due to
Streptococcus pyogenes is associated with what host reaction?

Back 12

Pyogenic inflammation

Front 13

DOC of acute bacterial pharyngitis in a pt w/ Pen allergy

Back 13

Erythromycin > clindamycin

Front 14

Pyogenic complication of streptococcal pharyngitis

Back 14

Tonsillar abscess

Front 15

Toxigenic complication of streptococcal pharyngitis

Back 15

Scarlet fever >> TSS (rare)

Front 16

Immunological complication of streptococcal pharyngitis

Back 16

Acute rheumatic fever

Front 17

Cause of fever, red throat + purulent exudate -
pseudomembrane with lymphadenopathy, in a pt from Russia

Back 17

Corynebacterium diphtheriae

Front 18

Gram/special stain of Corynebacterium diphtheriae should reveal

Back 18

Gram(+) rods w/
metachromatic granules

Front 19

Virulence genotype of Corynebacterium diphtheriae is acquired by

Back 19

Transduction (phage mediated transfer of exotoxin gene)

Front 20

Isolate on tellurite agar culture of throat swab for a cause of diphtheria is confirmed by

Back 20

Immunodiffusion (ELEK) assay for toxin

Front 21

Mechanism of action of exotoxin of Corynebacterium diphtheriae

Back 21

ADP ribosylation of EF-2 (protein synthesis block).

Front 22

Damage to pharynx and cardiac myosites due to
Corynebacterium diphtheriae is mediated by

Back 22

Cytotoxicity of A-B toxin

Front 23

Virologic Dx of URI symptoms, fever; red throat + purulent exudate; hepato-splenomegaly, lymphadenopathy, in a teenager, is confirmed by

Back 23

heterophile antibody (+)

Front 24

Host cells preferentially infected by EBV are

Back 24

B cells

Front 25

EBV is biologically similar to what class of viruses?

Back 25

herpes viruses

Front 26

Host immune system controls the EBV infection, mediated
by

Back 26

CD8+ T lymphocytes

Front 27

Rash occurs following which antibiotic(s) to treat infectious mononucleosis?

Back 27

amoxicillin

Front 28

Burkitt's lymphoma in some African population is a B-cell
tumor due to oncogenesis by

Back 28

EBV

Front 29

Nasopharyngeal carcinoma, a B-cell tumor that is common
in the Oriental population that consumes preserved fish, is due to oncogenesis by

Back 29

EBV

Front 30

Heterophile-negative infectious mononucleosis syndrome is
due to ?

Back 30

CMV

Front 31

Gram-positive bacteria that cause acute otitis media (AOM)

Back 31

Streptococcus pneumoniae

Front 32

Gram-negative diplococci bacteria that cause AOM

Back 32

Moraxellar catarrhalis

Front 33

Gram-negative coccobacilli bacteria that cause AOM

Back 33

Haemophilus influenzae

Front 34

> 7 days of nasal obstruction, rhinorrhea; purulent nasal
drainage + frontal pain/tenderness is treated with

Back 34

Amoxicillin & Clavulanate

Front 35

DOC for acute mastoiditis in a young child is amoxicillin &
clavulanate; why?

Back 35

Same etiology as AOM

Front 36

Cause of “seal-like barking” cough + episodic aphonia w/
symptoms of URI in a child

Back 36

parainfluenza virus