Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
23 Cards in this Set
- Front
- Back
|
A woman with obstetric infection has fever > 102oF, SBP <
90; diffuse sunburn-like rash or desquamation of palms and soles; multisystem Sx/Sns; vomiting, and diarrhea; blood culture negative. TOW? |
Staphylococcal Toxic shock Syndrome
|
|
|
What is the toxin associated with staphylococcal toxic shock syndrome?
|
TSST-1 (a superantigen)
|
|
|
Cause of severe, watery diarrhea in a woman with toxic shock syndrome?
|
Enterotoxin (coregulated with TSST-1)
|
|
|
Cause of toxic shock syndrome, which responds to vancomycin and clindamycin?
|
MRSA
|
|
|
Hx: in a man w/ necrotizing fasciitis or myositis or gangrene, fever > 38.9oC, SBP < 90 ; diffuse sunburn-like rash or desquamation of palms and soles.. Multisystem involvement. Blood culture positive. TOW?
|
Streptococcal toxic shock syndrome
|
|
|
What is the toxin associated with streptococcal toxic shock syndrome?
|
SpeA (superantigen)
|
|
|
DOC for streptococcal toxic shock syndrome
|
PenG + clindamycin
|
|
|
Hx: Fever, chills, and hypotensive. Blood culture yields a
GNR, oxidase (-), lactose fermenting organism on MacConkey agar. Immunological mediators of sepsis. |
IL-1 and TNF
|
|
|
DOC for a line-associated infection in a pt w/ GI tumor; lab: positive blood cultures and #-D-glucan antigenemia?
|
Fluconazole
|
|
|
DOC for a neutropenic pt w/ line-associated infection w/
immune suppression (hematologic malignancy, organ or hematopoietic stem cell transplantation, chemotherapy); w/ positive blood cultures and #-D-glucan antigenemia? |
Caspofungin
|
|
|
Cause of mononucleosis-like dz with fever, myalgia/arthralgia w/ lab: leukopenia, LFT abnls, in a pt w/ solid organ transplant?
|
CMV
|
|
|
Lung biopsy reveals large cells with nuclear inclusions
(Cowdry owl's eyes inclusion bodies) in a pt with AIDS and interstitial pneumonia. TOW? |
CMV
|
|
|
DOC for CMV antigenemia in a febrile pt with solid organ transplant?
|
Gancyclovir
|
|
|
Cause of hematuria, hemorrhagic cystitis, or ureteric stenosis, or interstitial nephritis in a severly immunocompromised pt?
|
BK virus
|
|
|
DOC for a pt w/ travel hx (back from the tropics), who has flu-like symptoms; splenomegaly; lab: CBC: anemia, thrombocytopenia, hypoglycemia. Blood smear: enlarged RBCs and Schuffner dots.
|
mefloquine + primaquine
|
|
|
Which drug is contraindicated in specific Tx of liver form of malaria in pts w/ G6PD deficiency?
|
Primaquine
|
|
|
DOC for a pt w/ travel hx (back from the tropics), who has flu-like symptoms (fever > 103oF), seizure, hyperparasitemia (>2.5% of RBC), pulmonary edema, or renal failure, or severe anemia?
|
quinidine and doxycycline.
|
|
|
Cause of malaria-like illness in an immunosuppressed pt w/o travel hx; lab: blood smear has cross-over rings in the RBCs?
|
Babesia spp.
|
|
|
A pt from S. America has a week-long fever, anorexia, lymphadenopathy, mild hepatosplenomegaly, and myocarditis; a nodular lesion on the arm. Blood smear should reveal motile species of what?
|
Trypanosoma cruzi
|
|
|
Cause of a chronic-stage systemic dz w/ cardiomyopathy,
megaesophagus, megacolon, and weight loss in a pt from S. America, who does not respond to nifurtimox. |
Trypanosoma cruzi
|
|
|
Cause of protracted fever and Crohn’s, celiac dz, ocular problems, and lymphadenopathy; duodenal biopsy demonstrating foamy macrophages in lamina propria?
|
Tropheryma whipplei
|
|
|
What is the most common cause of bacteremia associated w/ foreign device (prostheses, intravenous cathether, or central lines) in co-morbid, hospitalized pts?
|
Staphylococcus epidermidis
|
|
|
What is the cause of infections associated w/ ventilator support of respiration in co-morbid pts in the ICU?
|
Pseudomonas aeruginosa
|
