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17 Cards in this Set

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Oral Cavity Flora: Describe Niches available

What promotes growth
heterogeneous aerobic and anaerobic

High concentrations of nutrients near surface
Describe tooth structure and why unique habitat
Consists of mineral matrix (enamal) surrounding by living tissue ( dentin and palp)

tooth composed of calcium crystals, and not cells, therefor no active immune system
Define dextran and its effects
produced by streptococcus mutants from sucrose

aids in attachments of microbes to tooth surface from extracellular matrix creating a aerobic surface and anerobic environment underneath dextran build up

attached microbes (S. mutants and lactobicilli) ferment sucrose to produce lactic acid

Lactic acid demineralizes tooth enamel by solubilizing calcium
define lactic acid and its effects
Lactic acid demineralizes tooth enamel by solubilizing calcium

microbes attached to dextram (S. mutants and lactobicilli) ferment sucrose to produce lactic acid
floride strengthens tooth and makes tooth more resistant to lactic acid
How to microbes colonize tooth surface?
by attaching to acidic glycoproteins deposited by saliva
How does dental plaque develop?
Streptococcus mutants attach to acidic glycoproteins deposited by saliva.

S. mutants use sucrose to synthesize dextran, which aids attachements of other bacteria

as more bacteria attach, more dextran is produced, creating a aerobic and anaerobic environment
Streptococcus mutants
produced dextran from sucrose on tooth = plaque

establishes microbial colony
Why is there a diversity of microorganisms in the GI tract?
Diversity of environments.

varying in pH and oxygen levels
Describe conditions of human colon
ph 7 , very low oxygen

strict anaerobes and facultative aerobes present

site of cellulose breakdown by ruminococcus
Describe the types of microorganism in the human colon
(1) ones that digest complex carbohydrates (cellulose, starch) and produce VFA
(2) large intestinal microorganisms that ferment VFA to produce CO2 and H2
(3) methanogens that convert CO2 and H2 into methane (CH4) --only in 1/3 of adults
(4) sulfate reducers that ferment cystine and methionine (contain S) and produce h2S -- h2S is responsible for smell when they interact with other organic compounds
Explain how microorganisms contribute to maturation of the GI tract
important for early development, health and predisposition for diesease

absence of certain worms in GI tract linked to allergies

more methanogens = fatty
--because all excess H produced are converted to methane and do not black fermination and thus increase VFA amounts
What to GI microorganisms provide to host
carry out essential metabolic reactions (ie breakdown of cellulose)

provide vitamins
Describe the microbiology of the respiratory tract
Upper RT: many microorganisms
nose and nasopharynx similar to mouth (staphylococci, strptococci, cortnebacteria)

nasopharynx may harbor potential pathogens but immune system has them under control ==Healthy Carrier


Lowe RT: sterile in healthy individuals

special mechanism and immune system prevent colonization
True or False:

Bacteria can be non-pathogenic at one site but pathogenic at another
True

Ex. normal microbes of the vaginal tract ( i.e. proteus mirabillus) will cause infection in the the urinary tract and bladder
Genitourinary Tract microbiology and why?
generally sterile

due to flushing of urine
Vaginal Tract:

Why does the microbiota of sexual mature differ from non-sexual mature/active
Hormones control the concentrations of glycogen of vaginal epithelium

When sexually mature the concentration of glycogen in higher. Microorganisms take advantage and convert glycogen into lactic acid

increased lactic acid make the vagina more acidic (4.5 ph) and therefore helps prevent infection
7 sterile zones
Blood
Spinal Fluid
Internal portion of Urinary and Reproductive Tract
Peritoneal (gut)
Pleural (Lungs
Sinus
Interior of body tissues (bones, muscles)