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15 Cards in this Set

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V. cholerae has a better colonization efficiency in individuals of which blood group?
better colonization efficiency in blood group O individuals, more sensitive than A, B, or AB Blood types (seem to cover up some receptors that bacteria likes to bind to
Where is the "P Pilli" found and what does it do?
"pyelonephritis pili" found on UTI causing e. Coli

the host receptor is α-D galactopyranosyl-(1-4)-β-D-galactopyranoside moiety found in glycolipids of urinary epithelial cells
Major parts of P Pillus
papA = major subunit anchored to Outer Membrane
PapG = protein on top of PapA that interacts with ADHESIN (host cell sugar)
how does M. TB successfully infect host?
taken up by Macrophage
subverts phagosome pathway between early and late phagosome (Rab 7 is not recruited)
adherence
process by which bacteria stick to host surfaces

adhesion = initial step in infection
carrier
person or animal with asymptomatic infection or colonization that can be transmitted to another susceptible person or animal
infection
multiplication of an infectious agent within the body
invasion
the process by which the pathogen enters host cells or tissues and spread to other sites in the body
nonpathogen
a microorganism that does not cause disease, may be part of the normal flora (e.g. lactococcus)
opportunistic pathogen
an infectious agent capable of causing disease only when host resistance is impaired (e.g. Staph aureus and Pseudomonis aeruginosa, and fungi)
Pathogen
microorganism capable of causing disease
pathogenicity
the ability of an infectious agent to cause disease
pathogenesis
the process by which an infectious agent causes disease
toxigenicity
the ability of a microorganism to produce a toxin that contributes to the dvpt of disease
virulence
the overall ability of an agent to cause disease, virulence involves adherence, invasion and toxigenicity