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26 Cards in this Set

  • Front
  • Back
E. coli is lactose ___
+
E. coli is grouped based on _______
surface antigens
most normal flora E. coli are ______ in intestinal tract
non-pathogenic
pathogenic strains of e-coli produce virulence factors
found on:
plasmids
bacteriophages
pathogenicity islands
virulence factors include
fimbriae
secretion systems
toxins
DESTRUCTION OF SURFACE MICROVILLI IN SMALL INTESTINES
fever
diarrhea (infantile)
vomiting/nausea
non-bloody stools
common in developing countries (rare in U.S.)
Enteropathogenic E. coli (EPEC)
EPEC Steps in pathogenicity:
1. BFP
2. Type III SS
3. Signaling
4. Actin: A& E
EPEC is primarily a dz of ________

________ has a protective effect
the young (<6mo)

breast feeding
traveler’s diarrhea
ETEC
ETEC heat labile toxin
AB toxin
ETEC symptom
watery diarrhea
ETEC is self limiting and exposure results in ______
immunity
usually O157:H7
Enterohemorrhagic E. coli (EHEC)
“shiga-like” toxin (cytotoxin); phage gene
Vero toxin (VTEC)
hemorrhagic colitis
EHEC
pt who just ate at jack-in-the-box complains of bloody diarrhea. His urine has blood in it as well. He is afebrile. What is the dx
EHEC
In EHEC _____ seem to be the major reservoir
cattle
0157 strains of EHEC do not ferment _______
sorbitol
with EHEC do not use _____ just provide supportive tx
ABs
Enteroinvasive E. coli (EIEC )is a common cause of
dysentery
EIEC bacteria can cause______ formation that allows spread from one cell to another
“actin tail”
associated with persistent watery diarrhea
> 14 days (especially infants)
Enteroaggregative E. coli (EAEC )
Enteroaggregative E. coli (EAEC )have ____ to allow for bacteria to stack up on each other
fimbriae
Enteroaggregative E. coli (EAEC )bacteria stimulate mucous production = _______(bacterial community)
biofilm formation
Uropathogenic E. coli (UPEC) is the most common cause of _____
UTIs
Uropathogenic E. coli (UPEC)produce _____ that
preferentially binds to
uroepithelial cells
pili