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26 Cards in this Set
- Front
- Back
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E. coli is lactose ___
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+
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E. coli is grouped based on _______
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surface antigens
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most normal flora E. coli are ______ in intestinal tract
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non-pathogenic
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pathogenic strains of e-coli produce virulence factors
found on: |
plasmids
bacteriophages pathogenicity islands |
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virulence factors include
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fimbriae
secretion systems toxins |
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DESTRUCTION OF SURFACE MICROVILLI IN SMALL INTESTINES
fever diarrhea (infantile) vomiting/nausea non-bloody stools common in developing countries (rare in U.S.) |
Enteropathogenic E. coli (EPEC)
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EPEC Steps in pathogenicity:
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1. BFP
2. Type III SS 3. Signaling 4. Actin: A& E |
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EPEC is primarily a dz of ________
________ has a protective effect |
the young (<6mo)
breast feeding |
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traveler’s diarrhea
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ETEC
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ETEC heat labile toxin
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AB toxin
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ETEC symptom
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watery diarrhea
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ETEC is self limiting and exposure results in ______
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immunity
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usually O157:H7
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Enterohemorrhagic E. coli (EHEC)
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“shiga-like” toxin (cytotoxin); phage gene
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Vero toxin (VTEC)
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hemorrhagic colitis
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EHEC
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pt who just ate at jack-in-the-box complains of bloody diarrhea. His urine has blood in it as well. He is afebrile. What is the dx
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EHEC
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In EHEC _____ seem to be the major reservoir
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cattle
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0157 strains of EHEC do not ferment _______
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sorbitol
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with EHEC do not use _____ just provide supportive tx
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ABs
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Enteroinvasive E. coli (EIEC )is a common cause of
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dysentery
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EIEC bacteria can cause______ formation that allows spread from one cell to another
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“actin tail”
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associated with persistent watery diarrhea
> 14 days (especially infants) |
Enteroaggregative E. coli (EAEC )
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Enteroaggregative E. coli (EAEC )have ____ to allow for bacteria to stack up on each other
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fimbriae
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Enteroaggregative E. coli (EAEC )bacteria stimulate mucous production = _______(bacterial community)
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biofilm formation
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Uropathogenic E. coli (UPEC) is the most common cause of _____
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UTIs
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Uropathogenic E. coli (UPEC)produce _____ that
preferentially binds to uroepithelial cells |
pili
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