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15 Cards in this Set

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Causes of antibiotic resistance

mutation


twice as many prescriptions that are prescribed


Antibiotics are sprayed on fields for agriculture- animal feed

Solutions for antibiotic resistance

1.Hospital precautions 2. ReducePrescriptions 3. appropriateàviral 4. Testing- organism, resistant. 5. Complete course6.Combining drugs when needed 7.Staying home 8. Reduce use in agriculture- buy local andorganic9. Advocate for more research onantibiotics
Selectivetoxicity: magic bullet (Irrlec)-
destroying the infective agent without harming the host’s cells.

Antibiotic source

fungal


bacteria

Selective toxicity:
magic bullet (Irrlec)- destroying the infectiveagent without harming the host’s cells. More toxic to the microbe because ofthe differences between humans and microbes: cell walls, enzyme, prokaryotic ribosome.

Cell wall antibiotics

i. Penicillin: semi synthetic (Cephalosporin:good for exchange of penicillin)

ii. Vancomycin iii. Bacitracin iv. TB. Isoniazid

A. Membranes antibiotics
Polymyxins
DNA/RNA antibiotics
i. Gyrase ii. Cipro

iii. Quinolones iv. Rifampin

A. Enzymemakes Folic Acid
Sulfadrugs
A. RibosomeTranslation
i. Erythromycin (Almost all broad spectrum) ii. Streptomycin, Gentamycin

iii. Chloramphenicol


iv. Tetracycline

Antimicrobials



Antifungals- mostly toxic and external

i. Nystatin: static to others

ii. Grisfuluin iii. Mycomazole: myco means fungus

Antiprotozoal
i. Antimalarial- Chlorquine(antimalarial) ii. GI Infection- Metronidazole
Streptococcus:
chain and cluster

a. Found in the nasal pharanx, but can migrate to the lungs and cause pneumonia


b. Prefers little to no oxygen, normal flora pharynx


c. Can’t tolerate salt


d. If strep becomes blood bocarditit, osteo kidneyrne: endo

Staphlocuccus areus:
a. MRSA

b. Skin- pimples, boils, carbuncle


C. Streptococcus: chain and cluster

Staphylococcusareus:
Bacteria enters through an open wound b. Cellulitis: causes damage to the deep tissues of the skin