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25 Cards in this Set
- Front
- Back
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viral disease of the UA tract are primarily
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2 STDs: herpes simplex virus II and human papilloma virus, no cures but recurrent disease may be reduced and surgical removal of infected areas may help s/s
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herpes simples virus II and human papilloma virus have reached
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pandemic proportions since the 1960s, sexual promiscuity increased. both infect/remain in host for life.
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transmissions of viral STDs
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any time in life of infected pt;
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Genital herpes characteristics
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viral STD; enveloped virion; DNA
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Herpes simplex virus II causes
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genital herpes which causes penile, vuvar and perianal infxns. recurrence common and esp painful in women w/ bouts qmo
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Herpes simplex II /genital herpes is spread via
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direct contact when lesions are apparent of not
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herpes simplex II/ genital herpes incidence
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5-600,000 new cases/y with 20mill affected in US
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genital herpes recurrence
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is common and is esp painful in women who have bouts Qmo
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prevention of genital herpes
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condom will usually prevent spread unless extragenital lesions present. condoms reduce transmission 10fold
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a mother with active lesions of genital herpes should
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have a C section to prevent disseminated disease of the newborn, a lethal or devastating disease
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the best drug for tx of all HSV infxns
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Acyclovir- it helps reduce severity and length of recurrent infxn and is esp useful for painful genital recurrences in which it works best if taken prophylactically
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herpes viruses are sometimes spread
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to the eye (herpetic keratitis)( where iodoxuridine is also helpful) and to the nervous system (encephalitis) where AraA (adenine arabinoside) is also useful for tx
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the antivirals used to tx HSV
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all act to inhibit viral DNA replication
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antivirals are of little help for
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disseminated disease of the newborn and the immunocompromised
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viral latency
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is not curable by any drug
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Genital Warts aka
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papilloma viruses
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characteristics of papilloma viruses/ genital warts
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naked, icosahedral virion; DNA
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most genital warts are
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benign tumors
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a few types of genital warts are found in
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over 95% of all cervical carcinomas, the cause of 35,000 deaths in the US/y
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Pap Smear
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the standard test for cervical ca is virtually a test for papilloma virus
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can HPV cause ca
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the HPV can't cause ca alone but require a cofactor, such as smoking, to provide the second and final chemical change that results in ca development
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normal tx for genital warts
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surgical removal
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because infection results in
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permanent residence of the virus and frequent transmissions, millions of Americans carry genital warts that infect many thousands of new people Qy
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most of the population with
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multiple sex partners (more than 4-5 partners) is apparently chronically infected with genital warts
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many people with genital warts are
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asymptomatic and spread the disease with no knowledge of it
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