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18 Cards in this Set
- Front
- Back
nonspecific defenses
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defenses against any pathogen AKA innate immunity
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first line of defense
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skin, mucous membranes
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second line of defense
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natural killer cells, phagocytes, inflammation, fever, and antimicrobial substances
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specific defenses
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defenses against a specific pathogen
aka adaptive immunity |
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third line of defense
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specific defenses. involved recognition of specific microbe. has a memory
cell mediated immune system (T cells) humoral immune system (B cells, antibodies) |
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enterics that infect urinary tract
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E. coli
Pseudomonas aeruninosa Staph saprophyticus - not enteric but found in waste |
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cystitis
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bladder inflammation - 8 times more common in women than men
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leptospiridosis
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infection of kidneys.
caused by a spirochete |
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sebum
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skin oil inhibits growth of some baceria
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lysozyme
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found in ears, saliva..
kills cells |
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phagocyosis
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ingestion of any particulate matter by a cell
white blood cell system = professional phagocytes 2nd line of defense of the body |
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Toll-like receptors (TLRs)
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receptors for stuff that we don't have.. like flagellin, LPS, bacterial DNA and stuff.
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Neutrophils
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60-70%
called polymorphonuclear neutrophils (PMNs) professional phagocytes the cops ! can leave blood and enter tissues |
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Basophils
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inflammation and allergies by releasing histamine
mas cells. fixed in tissues |
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Eosinophils
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involved in allergies
may be phagocytic involved in helminh infections |
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Dendritic cells
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Antigen presenting cells (APC's)
found in tissues and lymphs present antigens to T cells and stuff |
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monocytes
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spend 1-2 days in blood, then go to issues and become a macrophage
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macrophage
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professional phagocytes process antigens
secree biologically active compounds that regulate the immune system cause dialation of capillary beds... pain and swelling |