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18 Cards in this Set

  • Front
  • Back
nonspecific defenses
defenses against any pathogen AKA innate immunity
first line of defense
skin, mucous membranes
second line of defense
natural killer cells, phagocytes, inflammation, fever, and antimicrobial substances
specific defenses
defenses against a specific pathogen
aka adaptive immunity
third line of defense
specific defenses. involved recognition of specific microbe. has a memory

cell mediated immune system (T cells)
humoral immune system (B cells, antibodies)
enterics that infect urinary tract
E. coli
Pseudomonas aeruninosa
Staph saprophyticus - not enteric but found in waste
cystitis
bladder inflammation - 8 times more common in women than men
leptospiridosis
infection of kidneys.
caused by a spirochete
sebum
skin oil inhibits growth of some baceria
lysozyme
found in ears, saliva..
kills cells
phagocyosis
ingestion of any particulate matter by a cell
white blood cell system = professional phagocytes
2nd line of defense of the body
Toll-like receptors (TLRs)
receptors for stuff that we don't have.. like flagellin, LPS, bacterial DNA and stuff.
Neutrophils
60-70%
called polymorphonuclear neutrophils (PMNs)
professional phagocytes
the cops ! can leave blood and enter tissues
Basophils
inflammation and allergies by releasing histamine
mas cells. fixed in tissues
Eosinophils
involved in allergies
may be phagocytic
involved in helminh infections
Dendritic cells
Antigen presenting cells (APC's)
found in tissues and lymphs
present antigens to T cells and stuff
monocytes
spend 1-2 days in blood, then go to issues and become a macrophage
macrophage
professional phagocytes process antigens
secree biologically active compounds that regulate the immune system
cause dialation of capillary beds... pain and swelling