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5 Cards in this Set

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1. Campylobacter jejuni (enteric disease)

Short motile, comma-shaped or spiral gram-negative organisms
Requires 4 special conditions for isolation.
. These arc unique.
. Diminished oxygen (rnicroaerophilic), grow in increased C02
2. 42 degree incubation
3. Best isolated on selective media
4. May require extended incubation time
Can do... to detect ...
direct microscopy (darkfield)
-darting, corkscrew motility
-cases are
-dever and tucson study of fx
-third world
-how common in US
-how spread?
-sensitive to?

-afe Peak incidence of enteritis
-time peak in US
-see... in stool
A. Contaminated food and water, cases usually sporadic, may be outbreaks
B. Animal reservoirs include fowl, cattle, swine, sheep, dogs, cats, etc.

C. Denver and Tucson studies show it in 5-8%of diarrheal stool cultures. Other U.S. studies have shown up to 10-12%. Third world frequency up to 30%. Most common bacterial cause of diarrhea in the U.S.
D. Fecal-oral spread, sensitive to gastric acid. Requires 103to 106 organism inoculum. Also anal-genital-oral spread
E. is 1-5 year olds. Summer peaks in North America More frequent than combined total of Salmonella and Shigella.
F. intestinal mucosa. See WBCs and RBCs in stool samples
clinical disease

appearance of stool

-duration and relapse


-sheding of organism

-Infection produces what antiboidies
Rapid onset of fever, other constitutional symptoms, B. Abdominal pain in 90% of patients, especially in those with fever and anorexia, C. Some, < 50% have emesis, nausea, malaise, headache, myalgia
-diarrhea usually develops within 1 day of abdominal pain and fever (1-7 day incubation
2.Usually foul smelling, may be frankly bloody
1. Usually profuse, watery, may be mucoid, bile-stained

-May last 2-9 days, but usually 3-5 days

E. May have relapsing episodes. (Approximately 25% of untreated

-G. Spontaneous organism clearance usually in 3-6 weeks in untreated cases

-5-10% will continue to shed organisms in stool for year or longer (<3 weeks in 2/3 of patients)

- 1gG and IgM antibodies