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10 Cards in this Set
- Front
- Back
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rubeola
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measels
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rubeola properpties
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- ss, RNA, enveloped
-HA binds to CD46 (complment component) -F protein -effects children -respiratory droplets highly infectious -meningitis and encephalitis, secondary bacterial infections,SSPE (CNS disease), lethal - viral presentation, IgM ior IgG ( but IgG take 10 and 21 days) -koplick's sign -maculopapular rash -live attenuated MMR vaccine -passive immunized Ig for ones that have a compromised CMI or children under 1 years old |
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togaviridae
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rubella
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rubella properties
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-+ ss, RNA, linear, Enveloped
-inactivated by the environmental factors -mainly effects pregnant women and fetus -german measels= low fever, coryza, cervical and occipital lymphadenopathy -causes congenital ruibella= CNS, Heart, and Eyes infected -long infectious cycle, -infected infant is both a reservoir and host -maculopapular rash that spreads from the face to the trunk -Best Id'd by high levels of IgM -Live attenuated MMR vaccine that can cause problems for HIV patients or any other individual that has low CMI -rash develops due to formation of immune complex |
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B19
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parvoviridae
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B19 propeties
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- or + ss, DNA, naked
-causes fifth disease -binds to globoside also called the P-antigen and this is the receptor protein located on the eryhtropoetic cells -absolute requirement for the rapidly dividing cells, like immune cells or erythropoetic cells -slapped cheek rash -lacy endothelial rash -erythem infectiosum -can cause aplastic anemic event -main way to ID is show the S&S of 5th disease -IgG and IgM -mainly effects elementary age kids and the parents of the kids that have the B19 infections -no vaccine, however infection with B19 will give you life long immunity |
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what is the main differnce between B19 and Rubella when it comes to the infants
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rubella causes many congenital complications but B29 will cause hydrops fetalis or spontaneous abortion, so it is absolutely necessary to diagnose any B19 infections
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gamma virus genus
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herpes
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herpes 6 virus
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-ds, linear, enevloped virus
-buds of the nuclear membrane -the infected cells are much larger than the non-infected cells -infects humans -mainly 6-12 months old at risk -spreads via respiratory droplets -causes erythema subitum or rubeolla -rash usually due to imune complex and hypersensitivity -infantile fever= just fever no rash -most common cause of infantile exanthem -usually long life infections -no vaccine -infection provides long lasting immunity -mainly diagnosed with the presentation of the disease but that's at a time when the child has already begun to heal -no comlications |
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differnce between rash cause by measels and strep pyogenes
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pyo= scarlet fever, strwberry tongue, and pastia lines, and sand paper feel
measels= discrete rash, maculopapular rash |
